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Title: The Effect of Ag and Ag+N Ion Implantation on Cell Attachment Properties

Abstract

Implanted biomedical prosthetic devices are intended to perform safely, reliably and effectively in the human body thus the materials used for orthopedic devices should have good biocompatibility. Ultra High Molecular Weight Poly Ethylene (UHMWPE) has been commonly used for total hip joint replacement because of its very good properties. In this work, UHMWPE samples were Ag and Ag+N ion implanted by using the Metal-Vapor Vacuum Arc (MEVVA) ion implantation technique. Samples were implanted with a fluency of 1017 ion/cm2 and extraction voltage of 30 kV. Rutherford Backscattering Spectrometry (RBS) was used for surface studies. RBS showed the presence of Ag and N on the surface. Cell attachment properties investigated with model cell lines (L929 mouse fibroblasts) to demonstrate that the effect of Ag and Ag+N ion implantation can favorably influence the surface of UHMWPE for biomedical applications. Scanning electron microscopy (SEM) was used to demonstrate the cell attachment on the surface. Study has shown that Ag+N ion implantation represents more effective cell attachment properties on the UHMWPE surfaces.

Authors:
; ; ;  [1];  [2]; ;  [3];  [4]
  1. Bioengineering Department, Ege University, Bornova, Izmir 35100 (Turkey)
  2. Chemical Engineering Department, Izmir Institute of High Technology, Gulbahcekoyu Urla, Izmir (Turkey)
  3. High Current Electrnonics, Institute , Tomsk (Russian Federation)
  4. Center for Irradiation of Materials, Alabama A and M University, Normal, Huntsville AL 35762 (United States)
Publication Date:
OSTI Identifier:
21289588
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1099; Journal Issue: 1; Conference: CAARI 2008: 12. international conference on application of accelerators in research and industry, Fort Worth, TX (United States), 10-15 Aug 2008; Other Information: DOI: 10.1063/1.3120090; (c) 2009 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; 36 MATERIALS SCIENCE; BIOLOGICAL MATERIALS; FIBROBLASTS; ION BEAMS; ION IMPLANTATION; IRRADIATION; NITROGEN IONS; POLYETHYLENES; RADIATION EFFECTS; RUTHERFORD BACKSCATTERING SPECTROSCOPY; SCANNING ELECTRON MICROSCOPY; SILVER IONS; SURFACES

Citation Formats

Urkac, Emel Sokullu, Oztarhan, Ahmet, Gurhan, Ismet Deliloglu, Iz, Sultan Gulce, Tihminlioglu, Funda, Oks, Efim, Nikolaev, Alexey, and Ila, Daryush. The Effect of Ag and Ag+N Ion Implantation on Cell Attachment Properties. United States: N. p., 2009. Web. doi:10.1063/1.3120090.
Urkac, Emel Sokullu, Oztarhan, Ahmet, Gurhan, Ismet Deliloglu, Iz, Sultan Gulce, Tihminlioglu, Funda, Oks, Efim, Nikolaev, Alexey, & Ila, Daryush. The Effect of Ag and Ag+N Ion Implantation on Cell Attachment Properties. United States. doi:10.1063/1.3120090.
Urkac, Emel Sokullu, Oztarhan, Ahmet, Gurhan, Ismet Deliloglu, Iz, Sultan Gulce, Tihminlioglu, Funda, Oks, Efim, Nikolaev, Alexey, and Ila, Daryush. Tue . "The Effect of Ag and Ag+N Ion Implantation on Cell Attachment Properties". United States. doi:10.1063/1.3120090.
@article{osti_21289588,
title = {The Effect of Ag and Ag+N Ion Implantation on Cell Attachment Properties},
author = {Urkac, Emel Sokullu and Oztarhan, Ahmet and Gurhan, Ismet Deliloglu and Iz, Sultan Gulce and Tihminlioglu, Funda and Oks, Efim and Nikolaev, Alexey and Ila, Daryush},
abstractNote = {Implanted biomedical prosthetic devices are intended to perform safely, reliably and effectively in the human body thus the materials used for orthopedic devices should have good biocompatibility. Ultra High Molecular Weight Poly Ethylene (UHMWPE) has been commonly used for total hip joint replacement because of its very good properties. In this work, UHMWPE samples were Ag and Ag+N ion implanted by using the Metal-Vapor Vacuum Arc (MEVVA) ion implantation technique. Samples were implanted with a fluency of 1017 ion/cm2 and extraction voltage of 30 kV. Rutherford Backscattering Spectrometry (RBS) was used for surface studies. RBS showed the presence of Ag and N on the surface. Cell attachment properties investigated with model cell lines (L929 mouse fibroblasts) to demonstrate that the effect of Ag and Ag+N ion implantation can favorably influence the surface of UHMWPE for biomedical applications. Scanning electron microscopy (SEM) was used to demonstrate the cell attachment on the surface. Study has shown that Ag+N ion implantation represents more effective cell attachment properties on the UHMWPE surfaces.},
doi = {10.1063/1.3120090},
journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 1099,
place = {United States},
year = {2009},
month = {3}
}