skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Biliary Complications in Living Donor Liver Transplantation: Imaging Findings and the Roles of Interventional Procedures

Abstract

Purpose. To describe the incidence, types, and findings of biliary complications in living donor liver transplantation (LDLT) and to determine the roles of interventional procedures. Materials and methods. Twenty-four biliary complications among 161 LDLT patients (24/161, 14.9%) were identified. These complications were divided into two groups according to the initial manifestation time, i.e., 'early' (<60 days) or 'late'. The CT and cholangiographic findings were reviewed regarding the presence of a stricture or leak and the location, and length, shape, and degree of the stricture. Both groups were categorized into three subgroups: leak, stricture, and both. The type of interventional procedures used and their roles were determined. Results. Early complications were identified in 14 of the 24 patients (58%) and late complications in 11 (46%). One patient showed both early and late complications. Biliary stricture was detected in 10 patients, leak in 10, and both in 5. By cholangiography, all strictures were irregular and short (mean length 15 {+-} 6 mm) at the anastomotic site and complete obstruction was observed in 2 patients with late stricture. Twenty-three of the 24 patients were treated using percutaneous and/or endoscopic drainage procedures with or without balloon dilatation. Seventeen (74%) showed a good response, butmore » reoperations were inevitable in 6 (26%). All patients except those with complete obstruction showed a favorable outcome after interventional management. Conclusion. Biliary leaks and strictures are predominant complications in LDLT. Most show good responses to interventional treatment. However, complete obstruction needs additional operative management.« less

Authors:
; ; ; ; ; ; ;  [1]
  1. Seoul National University College of Medicine, Department of Radiology and Institute of Radiation Medicine (Korea, Republic of)
Publication Date:
OSTI Identifier:
21091322
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 28; Journal Issue: 6; Other Information: DOI: 10.1007/s00270-004-0262-7; Copyright (c) 2005 Springer Science+Business Media, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BILIARY TRACT; DRAINAGE; IMAGE PROCESSING; IMAGES; LEAKS; LIVER; PATIENTS

Citation Formats

Chang, Jung Min, Lee, Jeong Min, Suh, Kyung Suk, Yi, Nam Joon, Kim, Yong Tae, Kim, Se Hyung, Han, Joon Koo, E-mail: hanjk@radcom.snu.ac.kr, and Choi, Byung Ihn. Biliary Complications in Living Donor Liver Transplantation: Imaging Findings and the Roles of Interventional Procedures. United States: N. p., 2005. Web. doi:10.1007/S00270-004-0262-7.
Chang, Jung Min, Lee, Jeong Min, Suh, Kyung Suk, Yi, Nam Joon, Kim, Yong Tae, Kim, Se Hyung, Han, Joon Koo, E-mail: hanjk@radcom.snu.ac.kr, & Choi, Byung Ihn. Biliary Complications in Living Donor Liver Transplantation: Imaging Findings and the Roles of Interventional Procedures. United States. doi:10.1007/S00270-004-0262-7.
Chang, Jung Min, Lee, Jeong Min, Suh, Kyung Suk, Yi, Nam Joon, Kim, Yong Tae, Kim, Se Hyung, Han, Joon Koo, E-mail: hanjk@radcom.snu.ac.kr, and Choi, Byung Ihn. Thu . "Biliary Complications in Living Donor Liver Transplantation: Imaging Findings and the Roles of Interventional Procedures". United States. doi:10.1007/S00270-004-0262-7.
@article{osti_21091322,
title = {Biliary Complications in Living Donor Liver Transplantation: Imaging Findings and the Roles of Interventional Procedures},
author = {Chang, Jung Min and Lee, Jeong Min and Suh, Kyung Suk and Yi, Nam Joon and Kim, Yong Tae and Kim, Se Hyung and Han, Joon Koo, E-mail: hanjk@radcom.snu.ac.kr and Choi, Byung Ihn},
abstractNote = {Purpose. To describe the incidence, types, and findings of biliary complications in living donor liver transplantation (LDLT) and to determine the roles of interventional procedures. Materials and methods. Twenty-four biliary complications among 161 LDLT patients (24/161, 14.9%) were identified. These complications were divided into two groups according to the initial manifestation time, i.e., 'early' (<60 days) or 'late'. The CT and cholangiographic findings were reviewed regarding the presence of a stricture or leak and the location, and length, shape, and degree of the stricture. Both groups were categorized into three subgroups: leak, stricture, and both. The type of interventional procedures used and their roles were determined. Results. Early complications were identified in 14 of the 24 patients (58%) and late complications in 11 (46%). One patient showed both early and late complications. Biliary stricture was detected in 10 patients, leak in 10, and both in 5. By cholangiography, all strictures were irregular and short (mean length 15 {+-} 6 mm) at the anastomotic site and complete obstruction was observed in 2 patients with late stricture. Twenty-three of the 24 patients were treated using percutaneous and/or endoscopic drainage procedures with or without balloon dilatation. Seventeen (74%) showed a good response, but reoperations were inevitable in 6 (26%). All patients except those with complete obstruction showed a favorable outcome after interventional management. Conclusion. Biliary leaks and strictures are predominant complications in LDLT. Most show good responses to interventional treatment. However, complete obstruction needs additional operative management.},
doi = {10.1007/S00270-004-0262-7},
journal = {Cardiovascular and Interventional Radiology},
number = 6,
volume = 28,
place = {United States},
year = {Thu Dec 15 00:00:00 EST 2005},
month = {Thu Dec 15 00:00:00 EST 2005}
}