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Title: Radiofrequency Ablation with a New Perfused-Cooled Electrode Using a Single Pump: An Experimental Study in Ex Vivo Bovine Liver

Abstract

The purpose of this study was to assess the efficacy of a new perfused-cooled electrode that uses a single pump for creating a large ablation zone in explanted bovine liver. This was done by comparing with the radiofrequency (RF) ablation zones that were created with a monopolar cooled electrode to the RF ablation zones that were created by the new perfused-cooled electrode. We developed a new perfused-cooled electrode that uses a single pump by modifying a 17-gauge cooled electrode (Radionics) with a 2.5-cm outer metallic sheath (15-gauge) in order to allow use of the internal cooling water (5.85 % hypertonic saline) for the infused saline. Thirty ablation zones were created in explanted bovine livers (12-min ablation cycle; pulsed technique; 2000 mA, maximum) with three different regimens: group A, RF ablation with the 17-gauge cooled electrode; group B, RF ablation with the 15-gauge cooled electrode; group C, RF ablation with the perfused-cooled electrode. T2-weighted magnetic resonance (MR) imaging was obtained immediately after RF ablation for calculating volumes of the ablation zone. Following MR imaging, the ablation zones were excised and measured for transverse diameters and vertical diameters. The transverse diameter, vertical diameter, and the calculated volumes of the ablation zones onmore » MR imaging were compared among the groups. Ablation zones created with the perfused-cooled electrode (group C) were significantly larger than those created with the 17-gauge cooled electrode (group A) and the 15-gauge cooled electrode (group B) according to the transverse diameter and vertical diameter on the gross specimens (p < 0.05): 3.6 {+-} 0.38 cm and 4.4 {+-} 0.20 cm in group A, 3.7 {+-} 0.08 cm and 4.6 {+-} 0.16 cm in group B, and 5.4 {+-} 0.65 cm and 6.0 {+-} 0.56 cm in group C, respectively. On the MR imaging, the calculated volumes of the ablation zones in group C were significantly larger than those in groups A and B (p < 0.05): 23.1 {+-} 8.7 cm{sup 3} in group A, 28.9 {+-} 5.7 cm{sup 3} in group B, and 80.0 {+-} 34 cm{sup 3} in group C, respectively. A new perfused-cooled electrode using a single pump could efficiently increase the size of the ablation zone in liver compared with a monopolar cooled electrode, and this was due to its simultaneous use of internal cooling and saline infusion.« less

Authors:
 [1];  [2]
  1. Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Department of Radiology (Korea, Republic of), E-mail: radi@lycos.co.kr
  2. Ilsan Paik Hospital, Inje University School of Medicine, Department of Diagnostic Radiology (Korea, Republic of)
Publication Date:
OSTI Identifier:
21091304
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 28; Journal Issue: 6; Other Information: DOI: 10.1007/s00270-005-0047-7; Copyright (c) 2005 Springer Science+Business Media, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABLATION; CARDIOVASCULAR DISEASES; CATTLE; ELECTRODES; LIVER; PUMPS; RADIOWAVE RADIATION; VASCULAR DISEASES

Citation Formats

Kim, Seung Kwon, and Seo, Jung Wook. Radiofrequency Ablation with a New Perfused-Cooled Electrode Using a Single Pump: An Experimental Study in Ex Vivo Bovine Liver. United States: N. p., 2005. Web. doi:10.1007/S00270-005-0047-7.
Kim, Seung Kwon, & Seo, Jung Wook. Radiofrequency Ablation with a New Perfused-Cooled Electrode Using a Single Pump: An Experimental Study in Ex Vivo Bovine Liver. United States. doi:10.1007/S00270-005-0047-7.
Kim, Seung Kwon, and Seo, Jung Wook. Thu . "Radiofrequency Ablation with a New Perfused-Cooled Electrode Using a Single Pump: An Experimental Study in Ex Vivo Bovine Liver". United States. doi:10.1007/S00270-005-0047-7.
@article{osti_21091304,
title = {Radiofrequency Ablation with a New Perfused-Cooled Electrode Using a Single Pump: An Experimental Study in Ex Vivo Bovine Liver},
author = {Kim, Seung Kwon and Seo, Jung Wook},
abstractNote = {The purpose of this study was to assess the efficacy of a new perfused-cooled electrode that uses a single pump for creating a large ablation zone in explanted bovine liver. This was done by comparing with the radiofrequency (RF) ablation zones that were created with a monopolar cooled electrode to the RF ablation zones that were created by the new perfused-cooled electrode. We developed a new perfused-cooled electrode that uses a single pump by modifying a 17-gauge cooled electrode (Radionics) with a 2.5-cm outer metallic sheath (15-gauge) in order to allow use of the internal cooling water (5.85 % hypertonic saline) for the infused saline. Thirty ablation zones were created in explanted bovine livers (12-min ablation cycle; pulsed technique; 2000 mA, maximum) with three different regimens: group A, RF ablation with the 17-gauge cooled electrode; group B, RF ablation with the 15-gauge cooled electrode; group C, RF ablation with the perfused-cooled electrode. T2-weighted magnetic resonance (MR) imaging was obtained immediately after RF ablation for calculating volumes of the ablation zone. Following MR imaging, the ablation zones were excised and measured for transverse diameters and vertical diameters. The transverse diameter, vertical diameter, and the calculated volumes of the ablation zones on MR imaging were compared among the groups. Ablation zones created with the perfused-cooled electrode (group C) were significantly larger than those created with the 17-gauge cooled electrode (group A) and the 15-gauge cooled electrode (group B) according to the transverse diameter and vertical diameter on the gross specimens (p < 0.05): 3.6 {+-} 0.38 cm and 4.4 {+-} 0.20 cm in group A, 3.7 {+-} 0.08 cm and 4.6 {+-} 0.16 cm in group B, and 5.4 {+-} 0.65 cm and 6.0 {+-} 0.56 cm in group C, respectively. On the MR imaging, the calculated volumes of the ablation zones in group C were significantly larger than those in groups A and B (p < 0.05): 23.1 {+-} 8.7 cm{sup 3} in group A, 28.9 {+-} 5.7 cm{sup 3} in group B, and 80.0 {+-} 34 cm{sup 3} in group C, respectively. A new perfused-cooled electrode using a single pump could efficiently increase the size of the ablation zone in liver compared with a monopolar cooled electrode, and this was due to its simultaneous use of internal cooling and saline infusion.},
doi = {10.1007/S00270-005-0047-7},
journal = {Cardiovascular and Interventional Radiology},
number = 6,
volume = 28,
place = {United States},
year = {Thu Dec 15 00:00:00 EST 2005},
month = {Thu Dec 15 00:00:00 EST 2005}
}