Right Gastric Artery Embolization Prior to Treatment with Yttrium-90 Microspheres

doi:10.1007/S00270-006-0028-5

Title: Right Gastric Artery Embolization Prior to Treatment with Yttrium-90 Microspheres

Full Record
Similar

Abstract

Purpose. Intra-arterial infusion of yttrium-90 microspheres is a form of radiation treatment for unresectable hepatic neoplasms. Misdeposition of particles in the gastroduodenal area such as the right gastric artery (RGA) may occur with serious consequences. We present a series of patients who underwent a detailed vascular study followed by RGA embolization. Special emphasis is placed on anatomic variations and technical considerations .Methods. In a 1 year period, 27 patients were treated. Initial vascular evaluation was performed, with careful attention to anatomic variants or extrahepatic arterial supply, especially to the gastroduodenal area. Embolization of such arteries was planned if needed. RGA embolization was performed antegradely from the hepatic artery or retrogradely via the left gastric artery (LGA). Postprocedural follow-up included clinical interview and gastroscopy if necessary. Results. RGA embolization was performed in 9 patients presenting with primary (n = 3) or metastatic liver tumors (n 6). Six patients underwent antegrade RGA embolization and 3 had embolization done retrogradely via the LGA. Retrograde access was chosen for anatomic reasons. None of the patients complained of gastroduodenal symptoms. Conclusion. RGA embolization can help minimize the gastroduodenal deposition of radioactive particles. RGA embolization should routinely be carried out. The procedure can be performed, withmore »« less

Authors:

Cosin, Octavio; Bilbao, Jose Ignacio ^[1]; Alvarez, Sergio ^[2]; Luis, Esther de; Alonso, Alberto; Martinez-Cuesta, Antonio ^[3]

Clinica Universitaria de Navarra, Departamento de Radiologia (Spain), E-mail: jibilbao@unav.es
Hospital Pablo Tobon Uribe, Servicio de Radiologia (Colombia)
Clinica Universitaria de Navarra, Departamento de Radiologia (Spain)

Publication Date:: Thu Feb 15 00:00:00 EST 2007

OSTI Identifier:: 21091053

Resource Type:: Journal Article

Resource Relation:: Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 30; Journal Issue: 1; Other Information: DOI: 10.1007/s00270-006-0028-5; Copyright (c) 2007 Springer Science+Business Media, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; EVALUATION; INFUSION; LIVER; METASTASES; MICROSPHERES; NEOPLASMS; PATIENTS; SYMPTOMS; YTTRIUM 90

Citation Formats


                    Cosin, Octavio, Bilbao, Jose Ignacio, Alvarez, Sergio, Luis, Esther de, Alonso, Alberto, and Martinez-Cuesta, Antonio. Right Gastric Artery Embolization Prior to Treatment with Yttrium-90 Microspheres.  United States: N. p., 2007. 
        Web.  doi:10.1007/S00270-006-0028-5.

Copy to clipboard


                    Cosin, Octavio, Bilbao, Jose Ignacio, Alvarez, Sergio, Luis, Esther de, Alonso, Alberto, & Martinez-Cuesta, Antonio. Right Gastric Artery Embolization Prior to Treatment with Yttrium-90 Microspheres.  United States.  doi:10.1007/S00270-006-0028-5.

Copy to clipboard


                    Cosin, Octavio, Bilbao, Jose Ignacio, Alvarez, Sergio, Luis, Esther de, Alonso, Alberto, and Martinez-Cuesta, Antonio. Thu .  
        "Right Gastric Artery Embolization Prior to Treatment with Yttrium-90 Microspheres".  United States.  
        doi:10.1007/S00270-006-0028-5.

Copy to clipboard


                    
@article{osti_21091053,

  title        = {Right Gastric Artery Embolization Prior to Treatment with Yttrium-90 Microspheres},

  author       = {Cosin, Octavio and Bilbao, Jose Ignacio and Alvarez, Sergio and Luis, Esther de and Alonso, Alberto and Martinez-Cuesta, Antonio},

  abstractNote = {Purpose. Intra-arterial infusion of yttrium-90 microspheres is a form of radiation treatment for unresectable hepatic neoplasms. Misdeposition of particles in the gastroduodenal area such as the right gastric artery (RGA) may occur with serious consequences. We present a series of patients who underwent a detailed vascular study followed by RGA embolization. Special emphasis is placed on anatomic variations and technical considerations .Methods. In a 1 year period, 27 patients were treated. Initial vascular evaluation was performed, with careful attention to anatomic variants or extrahepatic arterial supply, especially to the gastroduodenal area. Embolization of such arteries was planned if needed. RGA embolization was performed antegradely from the hepatic artery or retrogradely via the left gastric artery (LGA). Postprocedural follow-up included clinical interview and gastroscopy if necessary. Results. RGA embolization was performed in 9 patients presenting with primary (n = 3) or metastatic liver tumors (n 6). Six patients underwent antegrade RGA embolization and 3 had embolization done retrogradely via the LGA. Retrograde access was chosen for anatomic reasons. None of the patients complained of gastroduodenal symptoms. Conclusion. RGA embolization can help minimize the gastroduodenal deposition of radioactive particles. RGA embolization should routinely be carried out. The procedure can be performed, with similar technical success, by both anterograde and retrograde approaches.},

  doi          = {10.1007/S00270-006-0028-5},

  journal      = {Cardiovascular and Interventional Radiology},

  number       = 1,

  volume       = 30,

  place        = {United States},

  year         = {Thu Feb 15 00:00:00 EST 2007},

  month        = {Thu Feb 15 00:00:00 EST 2007}

}

Copy to clipboard

Journal Article:

DOI: 10.1007/S00270-006-0028-5

Other availability

Find in Google Scholar

Search WorldCat to find libraries that may hold this journal

Save / Share:

Export Metadata

Save to My Library

Treatment of Unresectable Primary and Metastatic Liver Cancer with Yttrium-90 Microspheres (TheraSphere (registered) ): Assessment of Hepatic Arterial Embolization

Sato, Kent ; Lewandowski, Robert J. ; Bui, James T. ; ... - Cardiovascular and Interventional Radiology

In Canada and Europe, yttrium-90 microspheres (TheraSphere); MDS Nordion, Ottawa, Canada) are a primary treatment option for primary and secondary hepatic malignancies. We present data from 30 patients with hepatocellular carcinoma (HCC) and metastatic liver disease treated with TheraSphere from a single academic institution to evaluate the angiographically evident embolization that follows treatment. Seven interventional radiologists from one treatment center compared pretreatment and posttreatment angiograms. The reviewers were blinded to the timing of the studies. The incidence of postembolization syndrome (PES) was determined as well as objective tumor response rates by the World Health Organization (WHO), Response Evaluation Criteria inmore »« less
DOI: 10.1007/S00270-005-0171-4
Histological Comparison of Kidney Tissue Following Radioembolization with Yttrium-90 Resin Microspheres and Embolization with Bland Microspheres

Silva, Suresh de, E-mail: suresh.desilva@unsw.edu.au ; Mackie, Simon ; Aslan, Peter ; ... - Cardiovascular and Interventional Radiology

BackgroundIntra-arterial brachytherapy with yttrium-90 ({sup 90}Y) resin microspheres (radioembolization) is a procedure to selectively deliver high-dose radiation to tumors. The purpose of this research was to compare the radioembolic effect of {sup 90}Y-radioembolization versus the embolic effect of bland microspheres in the porcine kidney model.MethodsIn each of six pigs, ~25–33 % of the kidney volume was embolized with {sup 90}Y resin microspheres and an equivalent number of bland microspheres in the contralateral kidney. Kidney volume was estimated visually from contrast-enhanced fluoroscopy imaging. Morphologic and histologic analysis was performed 8–9 weeks after the procedure to assess the locations of the microspheres and extentmore »« less
DOI: 10.1007/S00270-016-1482-3
Retained Contrast After Embolization of a Right Gastric Artery Pseudoaneurysm

Winick, Adam B. ; Malloy, Patrick C. ; Lund, Gunnar B. - Cardiovascular and Interventional Radiology

Pseudoaneurysms due to chronic pancreatitis can be a source of major gastrointestinal (GI) hemorrhage. Computed tomography (CT) is the primary diagnostic imaging modality for pancreatic pseudocysts associated with GI bleeding. Pseudoaneurysms and associated GI bleeding can be diagnosed and embolized with transcatheter techniques once the arterial anatomy is defined. CT is a useful modality for follow-up examination of the pseudocyst; the findings must be correlated with other procedures performed on these patients. On follow-up studies, contrast medium retained in the pseudocyst after embolization may falsely signal persistent bleeding into the pseudocyst.
DOI: 10.1007/S002709900025
EMBOLIZATION OF DOG PROSTATES WITH YTTRIUM-90 MICROSPHERES

Greene, W.M. - Journal of Urology (U.S.)

Experiments exploring means for the protection of adjacent normal tissue while delivering a destructive dose of radiation to malignant tissue were conducted. By injection of radioactive ceramic spheres or particles, too large to pass through capillaries or arteriovenous shunts, relatively high doses of radiation can be distributed homogeneously to a circumscribed area. Attempts were made to determine the uniformity of distribution and the radiation effect of varying doses of spheres injected into the arterial supply of the dog prostate. Nonradioactive and radioactive ceramic microspheres of 60 mu dia were used since this size exceeds the diameter of capillaries and arteriovenousmore »« less
Yttrium-90 microspheres for the treatment of hepatocellular carcinoma: A review

Salem, Riad ; Hunter, Russell D. - International Journal of Radiation Oncology, Biology and Physics

To present a critical review of yttrium-90 (TheraSphere) for the treatment of hepatocellular carcinoma (HCC). Medical literature databases (Medline, Cochrane Library, and CANCERLIT) were searched for available literature concerning the treatment of HCC with TheraSphere. These publications were reviewed for scientific and clinical validity. Studies pertaining to the use of yttrium-90 for HCC date back to the 1960s. The results from the early animal safety studies established a radiation exposure range of 50-100 Gy to be used in human studies. Phase I dose escalation studies followed, which were instrumental in delineating radiation dosimetry and safety parameters in humans. These earlymore »« less
DOI: 10.1016/j.ijrobp.2006.02.061