Transcatheter Arterial Chemoembolization of Liver Tumors: Effects of Embolization Protocol on Injectable Volume of Chemotherapy and Subsequent Arterial Patency
- Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, Maryland 21287, Russell H. Morgan Department ofRadiology (United States)
- Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, Maryland 21287, Russell H. Morgan Department of Radiology (United States)
- Baystate Medical Center, 759 Chestnut Street, Springfield, Massachusetts 01199, Department of Cardiovascular and Interventional Radiology (United States)
- Johns Hopkins University Schoolof Medicine, 600 North Wolfe Street, Baltimore, Maryland 21287, Russell H.Morgan Department of Surgery (United States)
The purpose of this study was to determine whether transcatheter arterial chemoembolization (TACE) protocol affects the total volume of chemotherapy injected into the liver as well as subsequent arterial patency. A total of 160 patients with primary or secondary liver cancer were treated with 3 different chemoembolization protocols at a single institution. Data were analyzed retrospectively.Group 1 (n = 36) consisted of slurry of chemotherapy,oil and polyvinyl alcohol particles (PVA), group 2 (n =91), chemotherapy and oil followed by PVA, and group 3(n = 33), chemotherapy and oil followed by Gelfoampledgets. The total volume of chemotherapy injected into the liver was recorded. Arterial patency was determined during subsequent chemoembolizations. The mean percentage of total intended chemotherapydose administered was 54.6% for group 1, 75.3% for group 2, and 80.6% for group 3. Arterial patency at follow-up angiography was 56% for group 1, 74% for group 2, and 81% for group 3. The slurry protocol (group 1) significantly reduced arterial patency and injectable volume of chemotherapy during TACE.
- OSTI ID:
- 21088411
- Journal Information:
- Cardiovascular and Interventional Radiology, Vol. 26, Issue 2; Other Information: DOI: 10.1007/s00270-002-2524-6; Copyright (c) 2003 Springer-Verlag New York, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
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