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Title: Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results

Abstract

Purpose: To test the percutaneous introducibility of the expandable vascular sheath (EVS) system and the safety of percutaneous balloon-assisted thrombectomy. Methods: The EVS was inserted directly (n= 9) or through a 9.5 Fr regular vascular introducer sheath (n= 9) into the femoral arteries and veins and carotid arteries in four dogs (18-21 kg). Balloon-assisted thrombectomies were simulated in iliac arteries. Histologic examinations were done at sites of funnel deployment immediately (n= 4) and 25 days (n= 8) after the intervention. Results: The EVS was successfully introduced into six of nine vessels by a direct percutaneous approach. Balloon-assisted thrombectomy using the EVS device caused localized intimal denudation, disruption of the internal elastic lamina, and mild hemorrhages into the media; one arterial dissection at the site of funnel deployment was seen. All indirect insertions and funnel deployments were successful. Twenty-five days after the experiments, intimal hyperplasia was noted in all cases. Conclusion: Percutaneous balloon-assisted thrombectomy may cause mild vascular injuries. Direct percutaneous introduction of the EVS device cannot be recommended yet.

Authors:
 [1];  [2];  [3]
  1. Klinik fuer Diagnostische Radiologie, Christian-Albrechts-Universitaet Kiel, Arnold Heller Strasse 9, D-24105 Kiel (Germany)
  2. Department of Pathology and Laboratory Medicine, VA Medical Center, 3350 Lojolla Village Drive, San Diego, CA 92161 (United States)
  3. Department of Radiology, University of California, 225 W. Dickinson St., San Diego, CA 91203 (United States)
Publication Date:
OSTI Identifier:
21080349
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 22; Journal Issue: 1; Other Information: DOI: 10.1007/s002709900327; Copyright (c) 1999 Springer-Verlag New York Inc; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CAROTID ARTERIES; DOGS; HEMORRHAGE; IN VIVO; INJURIES; VASCULAR DISEASES; VEINS

Citation Formats

Brossmann, Joachim, Haghighi, Parviz, and Bookstein, Joseph J. Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results. United States: N. p., 1999. Web. doi:10.1007/S002709900327.
Brossmann, Joachim, Haghighi, Parviz, & Bookstein, Joseph J. Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results. United States. https://doi.org/10.1007/S002709900327
Brossmann, Joachim, Haghighi, Parviz, and Bookstein, Joseph J. 1999. "Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results". United States. https://doi.org/10.1007/S002709900327.
@article{osti_21080349,
title = {Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results},
author = {Brossmann, Joachim and Haghighi, Parviz and Bookstein, Joseph J},
abstractNote = {Purpose: To test the percutaneous introducibility of the expandable vascular sheath (EVS) system and the safety of percutaneous balloon-assisted thrombectomy. Methods: The EVS was inserted directly (n= 9) or through a 9.5 Fr regular vascular introducer sheath (n= 9) into the femoral arteries and veins and carotid arteries in four dogs (18-21 kg). Balloon-assisted thrombectomies were simulated in iliac arteries. Histologic examinations were done at sites of funnel deployment immediately (n= 4) and 25 days (n= 8) after the intervention. Results: The EVS was successfully introduced into six of nine vessels by a direct percutaneous approach. Balloon-assisted thrombectomy using the EVS device caused localized intimal denudation, disruption of the internal elastic lamina, and mild hemorrhages into the media; one arterial dissection at the site of funnel deployment was seen. All indirect insertions and funnel deployments were successful. Twenty-five days after the experiments, intimal hyperplasia was noted in all cases. Conclusion: Percutaneous balloon-assisted thrombectomy may cause mild vascular injuries. Direct percutaneous introduction of the EVS device cannot be recommended yet.},
doi = {10.1007/S002709900327},
url = {https://www.osti.gov/biblio/21080349}, journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 1,
volume = 22,
place = {United States},
year = {Fri Jan 15 00:00:00 EST 1999},
month = {Fri Jan 15 00:00:00 EST 1999}
}