Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results
Abstract
Purpose: To test the percutaneous introducibility of the expandable vascular sheath (EVS) system and the safety of percutaneous balloon-assisted thrombectomy. Methods: The EVS was inserted directly (n= 9) or through a 9.5 Fr regular vascular introducer sheath (n= 9) into the femoral arteries and veins and carotid arteries in four dogs (18-21 kg). Balloon-assisted thrombectomies were simulated in iliac arteries. Histologic examinations were done at sites of funnel deployment immediately (n= 4) and 25 days (n= 8) after the intervention. Results: The EVS was successfully introduced into six of nine vessels by a direct percutaneous approach. Balloon-assisted thrombectomy using the EVS device caused localized intimal denudation, disruption of the internal elastic lamina, and mild hemorrhages into the media; one arterial dissection at the site of funnel deployment was seen. All indirect insertions and funnel deployments were successful. Twenty-five days after the experiments, intimal hyperplasia was noted in all cases. Conclusion: Percutaneous balloon-assisted thrombectomy may cause mild vascular injuries. Direct percutaneous introduction of the EVS device cannot be recommended yet.
- Authors:
-
- Klinik fuer Diagnostische Radiologie, Christian-Albrechts-Universitaet Kiel, Arnold Heller Strasse 9, D-24105 Kiel (Germany)
- Department of Pathology and Laboratory Medicine, VA Medical Center, 3350 Lojolla Village Drive, San Diego, CA 92161 (United States)
- Department of Radiology, University of California, 225 W. Dickinson St., San Diego, CA 91203 (United States)
- Publication Date:
- OSTI Identifier:
- 21080349
- Resource Type:
- Journal Article
- Journal Name:
- Cardiovascular and Interventional Radiology
- Additional Journal Information:
- Journal Volume: 22; Journal Issue: 1; Other Information: DOI: 10.1007/s002709900327; Copyright (c) 1999 Springer-Verlag New York Inc; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; CAROTID ARTERIES; DOGS; HEMORRHAGE; IN VIVO; INJURIES; VASCULAR DISEASES; VEINS
Citation Formats
Brossmann, Joachim, Haghighi, Parviz, and Bookstein, Joseph J. Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results. United States: N. p., 1999.
Web. doi:10.1007/S002709900327.
Brossmann, Joachim, Haghighi, Parviz, & Bookstein, Joseph J. Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results. United States. https://doi.org/10.1007/S002709900327
Brossmann, Joachim, Haghighi, Parviz, and Bookstein, Joseph J. 1999.
"Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results". United States. https://doi.org/10.1007/S002709900327.
@article{osti_21080349,
title = {Percutaneous Introducibility of the Expandable Vascular Sheath System and Injury Potential of Balloon-Assisted Thrombectomy: Preliminary In Vivo Results},
author = {Brossmann, Joachim and Haghighi, Parviz and Bookstein, Joseph J},
abstractNote = {Purpose: To test the percutaneous introducibility of the expandable vascular sheath (EVS) system and the safety of percutaneous balloon-assisted thrombectomy. Methods: The EVS was inserted directly (n= 9) or through a 9.5 Fr regular vascular introducer sheath (n= 9) into the femoral arteries and veins and carotid arteries in four dogs (18-21 kg). Balloon-assisted thrombectomies were simulated in iliac arteries. Histologic examinations were done at sites of funnel deployment immediately (n= 4) and 25 days (n= 8) after the intervention. Results: The EVS was successfully introduced into six of nine vessels by a direct percutaneous approach. Balloon-assisted thrombectomy using the EVS device caused localized intimal denudation, disruption of the internal elastic lamina, and mild hemorrhages into the media; one arterial dissection at the site of funnel deployment was seen. All indirect insertions and funnel deployments were successful. Twenty-five days after the experiments, intimal hyperplasia was noted in all cases. Conclusion: Percutaneous balloon-assisted thrombectomy may cause mild vascular injuries. Direct percutaneous introduction of the EVS device cannot be recommended yet.},
doi = {10.1007/S002709900327},
url = {https://www.osti.gov/biblio/21080349},
journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 1,
volume = 22,
place = {United States},
year = {Fri Jan 15 00:00:00 EST 1999},
month = {Fri Jan 15 00:00:00 EST 1999}
}