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Title: Numerical characterization of a tomographic system for online dose measurements in Boron Neutron Capture Therapy

Abstract

A tomographic system for online dose measurements in Boron Neutron Capture Therapy (BNCT) based on the measurement of a specific 478 keV {gamma}-ray emitted after the neutron capture in boron is being developed. In the present work we study by means of Monte Carlo numerical simulations the effects of the finite spatial resolution and the limited number of counts, i. e. the statistical noise, on the reconstructed image contrast of numerical phantoms. These phantoms, of simple geometry, mimic the tumor (specific) and the normal tissue (non specific) boron concentrations. The simulated projection data were reconstructed using the expectation-maximization maximum-likelihood algorithm. These studies will help in the improvement of BNCT dosimetry.

Authors:
; ;  [1];  [2];  [1];  [2];  [2];  [1];  [2];  [2]
  1. Escuela de Ciencia y Tecnologia (UNSAM), San Martin, Buenos Aires (Argentina)
  2. (Argentina)
Publication Date:
OSTI Identifier:
21054821
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 884; Journal Issue: 1; Conference: 6. Latin American symposium on nuclear physics and applications, Iguazu (Argentina), 3-7 Oct 2005; Other Information: DOI: 10.1063/1.2710586; (c) 2007 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
73 NUCLEAR PHYSICS AND RADIATION PHYSICS; ALGORITHMS; BORON 11 TARGET; CAPTURE; COMPUTERIZED SIMULATION; COMPUTERIZED TOMOGRAPHY; DOSES; DOSIMETRY; GAMMA RADIATION; KEV RANGE; MAXIMUM-LIKELIHOOD FIT; MONTE CARLO METHOD; NEOPLASMS; NEUTRON CAPTURE THERAPY; NEUTRON REACTIONS; NEUTRON SOURCES; PHANTOMS; PHOTON EMISSION; SPATIAL RESOLUTION

Citation Formats

Minsky, D. M., Valda, A. A., Somacal, H., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, Burlon, A. A., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, Fundacion J.B. Sauberan, Kreiner, A. J., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, and CONICET. Numerical characterization of a tomographic system for online dose measurements in Boron Neutron Capture Therapy. United States: N. p., 2007. Web. doi:10.1063/1.2710586.
Minsky, D. M., Valda, A. A., Somacal, H., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, Burlon, A. A., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, Fundacion J.B. Sauberan, Kreiner, A. J., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, & CONICET. Numerical characterization of a tomographic system for online dose measurements in Boron Neutron Capture Therapy. United States. doi:10.1063/1.2710586.
Minsky, D. M., Valda, A. A., Somacal, H., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, Burlon, A. A., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, Fundacion J.B. Sauberan, Kreiner, A. J., Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires, and CONICET. Mon . "Numerical characterization of a tomographic system for online dose measurements in Boron Neutron Capture Therapy". United States. doi:10.1063/1.2710586.
@article{osti_21054821,
title = {Numerical characterization of a tomographic system for online dose measurements in Boron Neutron Capture Therapy},
author = {Minsky, D. M. and Valda, A. A. and Somacal, H. and Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires and Burlon, A. A. and Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires and Fundacion J.B. Sauberan and Kreiner, A. J. and Dpto. de Fisica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica, Buenos Aires and CONICET},
abstractNote = {A tomographic system for online dose measurements in Boron Neutron Capture Therapy (BNCT) based on the measurement of a specific 478 keV {gamma}-ray emitted after the neutron capture in boron is being developed. In the present work we study by means of Monte Carlo numerical simulations the effects of the finite spatial resolution and the limited number of counts, i. e. the statistical noise, on the reconstructed image contrast of numerical phantoms. These phantoms, of simple geometry, mimic the tumor (specific) and the normal tissue (non specific) boron concentrations. The simulated projection data were reconstructed using the expectation-maximization maximum-likelihood algorithm. These studies will help in the improvement of BNCT dosimetry.},
doi = {10.1063/1.2710586},
journal = {AIP Conference Proceedings},
number = 1,
volume = 884,
place = {United States},
year = {Mon Feb 12 00:00:00 EST 2007},
month = {Mon Feb 12 00:00:00 EST 2007}
}