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Title: Synchrotron Radiation Mammography: Clinical Experimentation

Abstract

For several years a large variety of in-vitro medical imaging studies were carried out at the SYRMEP (Synchrotron Radiation for Medical Physics) beamline of the synchrotron radiation facility ELETTRA (Trieste, Italy) utilizing phase sensitive imaging techniques. In particular low dose Phase Contrast (PhC) in planar imaging mode and computed tomography were utilized for full field mammography. The results obtained on in-vitro samples at the SYRMEP beamline in PhC breast imaging were so encouraging that a clinical program on a limited number of patients selected by radiologists was launched to validate the improvements of synchrotron radiation in mammography. PhC mammography with conventional screen-film systems is the first step within this project. A digital system is under development for future applications. During the last years the entire beamline has been deeply modified and a medical facility dedicated to in-vivo mammography was constructed. The facility for PhC synchrotron radiation mammography is now operative in patient mode. The system reveals a prominent increase in image quality with respect to conventional mammograms even at lower delivered dose.

Authors:
; ; ; ;  [1];  [2]; ; ; ; ;  [3]; ;  [4]; ; ;  [5]
  1. Department of Physics, University of Trieste, Via A. Valerio 2, 34127 Trieste (Italy)
  2. (Italy)
  3. Sincrotrone Trieste SCpA, S.S. 14 km 163.5, 34012 Basovizza, Trieste (Italy)
  4. Health Physics, Hospital, Via Pieta 19, Trieste (Italy)
  5. Department of Radiology, University and Hospital, St. di Fiume 447, 34139 Trieste (Italy)
Publication Date:
OSTI Identifier:
21043392
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 879; Journal Issue: 1; Conference: 9. international conference on synchrotron radiation instrumentation, Daegu (Korea, Republic of), 28 May - 2 Jun 2006; Other Information: DOI: 10.1063/1.2436442; (c) 2007 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOMEDICAL RADIOGRAPHY; COMPUTERIZED TOMOGRAPHY; DIGITAL SYSTEMS; DOSES; FILMS; IMAGES; IN VITRO; IN VIVO; ITALY; MAMMARY GLANDS; PATIENTS; SYNCHROTRON RADIATION; X RADIATION

Citation Formats

Arfelli, Fulvia, Dreossi, Diego, Longo, Renata, Rokvic, Tatjana, Castelli, Edoardo, INFN, Via A. Valerio 2, 34127 Trieste, Abrami, Alessandro, Chenda, Valentina, Menk, Ralf-Hendrik, Quai, Elisa, Tromba, Giuliana, Bregant, Paola, De Guarrini, Fabio, Cova, Maria A., Tonutti, Maura, and Zanconati, Fabrizio. Synchrotron Radiation Mammography: Clinical Experimentation. United States: N. p., 2007. Web. doi:10.1063/1.2436442.
Arfelli, Fulvia, Dreossi, Diego, Longo, Renata, Rokvic, Tatjana, Castelli, Edoardo, INFN, Via A. Valerio 2, 34127 Trieste, Abrami, Alessandro, Chenda, Valentina, Menk, Ralf-Hendrik, Quai, Elisa, Tromba, Giuliana, Bregant, Paola, De Guarrini, Fabio, Cova, Maria A., Tonutti, Maura, & Zanconati, Fabrizio. Synchrotron Radiation Mammography: Clinical Experimentation. United States. doi:10.1063/1.2436442.
Arfelli, Fulvia, Dreossi, Diego, Longo, Renata, Rokvic, Tatjana, Castelli, Edoardo, INFN, Via A. Valerio 2, 34127 Trieste, Abrami, Alessandro, Chenda, Valentina, Menk, Ralf-Hendrik, Quai, Elisa, Tromba, Giuliana, Bregant, Paola, De Guarrini, Fabio, Cova, Maria A., Tonutti, Maura, and Zanconati, Fabrizio. Fri . "Synchrotron Radiation Mammography: Clinical Experimentation". United States. doi:10.1063/1.2436442.
@article{osti_21043392,
title = {Synchrotron Radiation Mammography: Clinical Experimentation},
author = {Arfelli, Fulvia and Dreossi, Diego and Longo, Renata and Rokvic, Tatjana and Castelli, Edoardo and INFN, Via A. Valerio 2, 34127 Trieste and Abrami, Alessandro and Chenda, Valentina and Menk, Ralf-Hendrik and Quai, Elisa and Tromba, Giuliana and Bregant, Paola and De Guarrini, Fabio and Cova, Maria A. and Tonutti, Maura and Zanconati, Fabrizio},
abstractNote = {For several years a large variety of in-vitro medical imaging studies were carried out at the SYRMEP (Synchrotron Radiation for Medical Physics) beamline of the synchrotron radiation facility ELETTRA (Trieste, Italy) utilizing phase sensitive imaging techniques. In particular low dose Phase Contrast (PhC) in planar imaging mode and computed tomography were utilized for full field mammography. The results obtained on in-vitro samples at the SYRMEP beamline in PhC breast imaging were so encouraging that a clinical program on a limited number of patients selected by radiologists was launched to validate the improvements of synchrotron radiation in mammography. PhC mammography with conventional screen-film systems is the first step within this project. A digital system is under development for future applications. During the last years the entire beamline has been deeply modified and a medical facility dedicated to in-vivo mammography was constructed. The facility for PhC synchrotron radiation mammography is now operative in patient mode. The system reveals a prominent increase in image quality with respect to conventional mammograms even at lower delivered dose.},
doi = {10.1063/1.2436442},
journal = {AIP Conference Proceedings},
number = 1,
volume = 879,
place = {United States},
year = {Fri Jan 19 00:00:00 EST 2007},
month = {Fri Jan 19 00:00:00 EST 2007}
}