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Title: Reducing the Dimensionality of the Inverse Problem in IMRT

Abstract

The inverse problem in IMRT (Intensity Modulated Radiation Therapy) consists in finding a set of radiation parameters based on the conditions given by the radiation therapist. The dimensionality of such problem usually depends on the number of bixels in which each radiation field is divided. Recently, the efforts have been put on finding arrangements of small segments (subfields) irradiating uniformly. In this paper a deterministic algorithm which allows to find solutions given a maximal number of segments is proposed. The procedure consists of two parts. In the first part the segments are chosen based on the irradiation geometry defined by the therapist. In the second part, the radiation intensity of the segments is optimized using standard optimization algorithms. Results are presented. Computational times were reduced and the final fluence maps were less complex without significantly sacrifying clinical value.

Authors:
 [1]
  1. Czech Technical University in Prague, Brehova 7, 115 19 Prague 1 (Czech Republic)
Publication Date:
OSTI Identifier:
21039407
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 958; Journal Issue: 1; Conference: 4. International summer school on nuclear physics methods and accelerators in biology and medicine, Prague (Czech Republic), 8-19 Jul 2007; Other Information: DOI: 10.1063/1.2825803; (c) 2007 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALGORITHMS; DETERMINISTIC ESTIMATION; GEOMETRY; IRRADIATION; MAPS; OPTIMIZATION; PLANNING; RADIOTHERAPY

Citation Formats

Cabal, Gonzalo. Reducing the Dimensionality of the Inverse Problem in IMRT. United States: N. p., 2007. Web. doi:10.1063/1.2825803.
Cabal, Gonzalo. Reducing the Dimensionality of the Inverse Problem in IMRT. United States. https://doi.org/10.1063/1.2825803
Cabal, Gonzalo. Mon . "Reducing the Dimensionality of the Inverse Problem in IMRT". United States. https://doi.org/10.1063/1.2825803.
@article{osti_21039407,
title = {Reducing the Dimensionality of the Inverse Problem in IMRT},
author = {Cabal, Gonzalo},
abstractNote = {The inverse problem in IMRT (Intensity Modulated Radiation Therapy) consists in finding a set of radiation parameters based on the conditions given by the radiation therapist. The dimensionality of such problem usually depends on the number of bixels in which each radiation field is divided. Recently, the efforts have been put on finding arrangements of small segments (subfields) irradiating uniformly. In this paper a deterministic algorithm which allows to find solutions given a maximal number of segments is proposed. The procedure consists of two parts. In the first part the segments are chosen based on the irradiation geometry defined by the therapist. In the second part, the radiation intensity of the segments is optimized using standard optimization algorithms. Results are presented. Computational times were reduced and the final fluence maps were less complex without significantly sacrifying clinical value.},
doi = {10.1063/1.2825803},
url = {https://www.osti.gov/biblio/21039407}, journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 958,
place = {United States},
year = {2007},
month = {11}
}