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Title: Resolution and noise trade-off analysis for volumetric CT

Journal Article · · Medical Physics
DOI:https://doi.org/10.1118/1.2779128· OSTI ID:21032790
; ;  [1]
  1. Applied Science Laboratory, General Electric Healthcare, Waukesha, Wisconsin 53188 (United States)

Until recently, most studies addressing the trade-off between spatial resolution and quantum noise were performed in the context of single-slice CT. In this study, we extend the theoretical framework of previous works to volumetric CT and further extend it by taking into account the actual shapes of the preferred reconstruction kernels. In the experimental study, we also attempt to explore a three-dimensional approach for spatial resolution measurement, as opposed to the conventional two-dimensional approaches that were widely adopted in previously published studies. By scanning a finite-sized sphere phantom, the MTF was measured from the edge profile along the spherical surface. Cases of different resolutions (and noise levels) were generated by adjusting the reconstruction kernel. To reduce bias, the total photon fluxes were matched: 120 kVp, 200 mA, and 1 s per gantry rotation. All data sets were reconstructed using a modified FDK algorithm under the same condition: Scan field-of-view (SFOV)=10 cm, and slice thickness=0.625 mm. The theoretical analysis indicated that the variance of noise is proportional to >4th power of the spatial resolution. Our experimental results supported this conclusion by showing the relationship is 4.6th (helical) or 5th (axial) power.

OSTI ID:
21032790
Journal Information:
Medical Physics, Vol. 34, Issue 10; Other Information: DOI: 10.1118/1.2779128; (c) 2007 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-2405
Country of Publication:
United States
Language:
English