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Title: Synthesis of amorphous calcium phosphate using various types of cyclodextrins

Abstract

Amorphous calcium phosphate (ACP) was synthesised in aqueous solution at room temperature using cyclodextrins. Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX) and thermal analysis (DTA/TGA) were performed on the calcium phosphate precipitates obtained from solutions. We observed that only {beta}-CD could stabilise the amorphous phase in the mother solution because of the lower solubility of {beta}-CD in water and the ACP remained stable in aqueous solution for more than 24 h at room temperature. The ACP particle has an initial particle size of less than 40 nm, Ca/P molar ratio of 1.67 and {beta}-CD absorbed on its surface. The mechanism for the stabilisation of ACP is proposed.

Authors:
 [1];  [1];  [2]
  1. Singapore-MIT Alliance, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 (Singapore)
  2. Singapore-MIT Alliance, School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 (Singapore). E-mail: mkctam@ntu.edu.sg
Publication Date:
OSTI Identifier:
21000628
Resource Type:
Journal Article
Resource Relation:
Journal Name: Materials Research Bulletin; Journal Volume: 42; Journal Issue: 5; Other Information: DOI: 10.1016/j.materresbull.2006.08.027; PII: S0025-5408(06)00355-2; Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; AMORPHOUS STATE; AQUEOUS SOLUTIONS; CALCIUM PHOSPHATES; CHEMICAL PREPARATION; DIFFERENTIAL THERMAL ANALYSIS; FOURIER TRANSFORMATION; INFRARED SPECTRA; NANOSTRUCTURES; PARTICLE SIZE; PARTICLES; PRECIPITATION; SOLUBILITY; TEMPERATURE RANGE 0273-0400 K; THERMAL GRAVIMETRIC ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; X-RAY DIFFRACTION; X-RAY SPECTROSCOPY

Citation Formats

Li Yanbao, Wiliana, Tjandra, and Tam, Kam C. Synthesis of amorphous calcium phosphate using various types of cyclodextrins. United States: N. p., 2007. Web.
Li Yanbao, Wiliana, Tjandra, & Tam, Kam C. Synthesis of amorphous calcium phosphate using various types of cyclodextrins. United States.
Li Yanbao, Wiliana, Tjandra, and Tam, Kam C. Thu . "Synthesis of amorphous calcium phosphate using various types of cyclodextrins". United States. doi:.
@article{osti_21000628,
title = {Synthesis of amorphous calcium phosphate using various types of cyclodextrins},
author = {Li Yanbao and Wiliana, Tjandra and Tam, Kam C.},
abstractNote = {Amorphous calcium phosphate (ACP) was synthesised in aqueous solution at room temperature using cyclodextrins. Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX) and thermal analysis (DTA/TGA) were performed on the calcium phosphate precipitates obtained from solutions. We observed that only {beta}-CD could stabilise the amorphous phase in the mother solution because of the lower solubility of {beta}-CD in water and the ACP remained stable in aqueous solution for more than 24 h at room temperature. The ACP particle has an initial particle size of less than 40 nm, Ca/P molar ratio of 1.67 and {beta}-CD absorbed on its surface. The mechanism for the stabilisation of ACP is proposed.},
doi = {},
journal = {Materials Research Bulletin},
number = 5,
volume = 42,
place = {United States},
year = {Thu May 03 00:00:00 EDT 2007},
month = {Thu May 03 00:00:00 EDT 2007}
}