Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy
- Department of Radiation Physics, City of Hope National Medical Center, Duarte, CA (United States) and Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA (United States)
- Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA (United States)
- Department of Radiation Physics, City of Hope National Medical Center, Duarte, CA (United States)
This study evaluated the efficacy of using helical tomotherapy for conformal avoidance treatment of anal adenocarcinoma. We retrospectively generated step-and-shoot intensity-modulated radiotherapy (sIMRT) plans and helical tomotherapy plans for two anal cancer patients, one male and one female, who were treated by the sIMRT technique. Dose parameters for the planning target volume (PTV) and the organs-at-risk (OARs) were compared between the sIMRT and the helical tomotherapy plans. The helical tomotherapy plans showed better dose homogeneity in the PTV, better dose conformity around the PTV, and, therefore, better sparing of nearby OARs compared with the sIMRT plans. In-vivo skin dose measurements were performed during conformal avoidance helical tomotherapy treatment of an anal cancer patient to verify adequate delivery of skin dose and sparing of OARs.
- OSTI ID:
- 20975199
- Journal Information:
- Medical Dosimetry, Vol. 32, Issue 1; Other Information: DOI: 10.1016/j.meddos.2006.10.004; PII: S0958-3947(06)00168-3; Copyright (c) 2007 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0958-3947
- Country of Publication:
- United States
- Language:
- English
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