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Title: Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy

Abstract

This study evaluated the efficacy of using helical tomotherapy for conformal avoidance treatment of anal adenocarcinoma. We retrospectively generated step-and-shoot intensity-modulated radiotherapy (sIMRT) plans and helical tomotherapy plans for two anal cancer patients, one male and one female, who were treated by the sIMRT technique. Dose parameters for the planning target volume (PTV) and the organs-at-risk (OARs) were compared between the sIMRT and the helical tomotherapy plans. The helical tomotherapy plans showed better dose homogeneity in the PTV, better dose conformity around the PTV, and, therefore, better sparing of nearby OARs compared with the sIMRT plans. In-vivo skin dose measurements were performed during conformal avoidance helical tomotherapy treatment of an anal cancer patient to verify adequate delivery of skin dose and sparing of OARs.

Authors:
 [1];  [2];  [3];  [4];  [3];  [4];  [2]
  1. Department of Radiation Physics, City of Hope National Medical Center, Duarte, CA (United States) and Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA (United States). E-mail: chan@coh.org
  2. Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA (United States)
  3. Department of Radiation Physics, City of Hope National Medical Center, Duarte, CA (United States)
  4. (United States)
Publication Date:
OSTI Identifier:
20975199
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Dosimetry; Journal Volume: 32; Journal Issue: 1; Other Information: DOI: 10.1016/j.meddos.2006.10.004; PII: S0958-3947(06)00168-3; Copyright (c) 2007 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; CARCINOMAS; COMPUTERIZED TOMOGRAPHY; DOSIMETRY; IN VIVO; PATIENTS; PLANNING; RADIATION DOSES; RADIOTHERAPY; SKIN; VERIFICATION

Citation Formats

Han Chunhui, Chen Yijen, Liu An, Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, Schultheiss, Timothy E., Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, and Wong, Jeffrey Y.C. Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy. United States: N. p., 2007. Web.
Han Chunhui, Chen Yijen, Liu An, Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, Schultheiss, Timothy E., Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, & Wong, Jeffrey Y.C. Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy. United States.
Han Chunhui, Chen Yijen, Liu An, Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, Schultheiss, Timothy E., Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, and Wong, Jeffrey Y.C. Sun . "Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy". United States. doi:.
@article{osti_20975199,
title = {Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy},
author = {Han Chunhui and Chen Yijen and Liu An and Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA and Schultheiss, Timothy E. and Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA and Wong, Jeffrey Y.C.},
abstractNote = {This study evaluated the efficacy of using helical tomotherapy for conformal avoidance treatment of anal adenocarcinoma. We retrospectively generated step-and-shoot intensity-modulated radiotherapy (sIMRT) plans and helical tomotherapy plans for two anal cancer patients, one male and one female, who were treated by the sIMRT technique. Dose parameters for the planning target volume (PTV) and the organs-at-risk (OARs) were compared between the sIMRT and the helical tomotherapy plans. The helical tomotherapy plans showed better dose homogeneity in the PTV, better dose conformity around the PTV, and, therefore, better sparing of nearby OARs compared with the sIMRT plans. In-vivo skin dose measurements were performed during conformal avoidance helical tomotherapy treatment of an anal cancer patient to verify adequate delivery of skin dose and sparing of OARs.},
doi = {},
journal = {Medical Dosimetry},
number = 1,
volume = 32,
place = {United States},
year = {Sun Apr 01 00:00:00 EDT 2007},
month = {Sun Apr 01 00:00:00 EDT 2007}
}