skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Interinstitutional Variations in Planning for Stereotactic Body Radiation Therapy for Lung Cancer

Abstract

Purpose: The aim of this study was to assess interinstitutional variations in planning for stereotactic body radiation therapy (SBRT) for lung cancer before the start of the Japan Clinical Oncology Group (JCOG) 0403 trial. Methods and Materials: Eleven institutions created virtual plans for four cases of solitary lung cancer. The created plans should satisfy the target definitions and the dose constraints for the JCOG 0403 protocol. Results: FOCUS/XiO (CMS) was used in six institutions, Eclipse (Varian) in 3, Cadplan (Varian) in one, and Pinnacle3 (Philips/ADAC) in one. Dose calculation algorithms of Clarkson with effective path length correction and superposition were used in FOCUS/XiO; pencil beam convolution with Batho power law correction was used in Eclipse and Cadplan; and collapsed cone convolution superposition was used in Pinnacle3. For the target volumes, the overall coefficient of variation was 16.6%, and the interinstitutional variations were not significant. For maximal dose, minimal dose, D95, and the homogeneity index of the planning target volume, the interinstitutional variations were significant. The dose calculation algorithm was a significant factor in these variations. No violation of the dose constraints for the protocol was observed. Conclusion: There can be notable interinstitutional variations in planning for SBRT, including both interobservermore » variations in the estimate of target volumes as well as dose calculation effects related to the use of different dose calculation algorithms.« less

Authors:
 [1];  [1];  [2];  [3];  [4];  [5];  [1];  [1];  [1];  [1];  [6];  [1]
  1. Department of Radiation Oncology and Image-applied Therapy, Kyoto University, Kyoto (Japan)
  2. Department of Radiation Oncology and Image-applied Therapy, Kyoto University, Kyoto (Japan). E-mail: nag@kuhp.kyoto-u.ac.jp
  3. Department of Radiology, Keio University, Tokyo (Japan)
  4. Radiation Oncology, Imaging and Diagnosis, Molecular and Organ Regulation, Sapporo Medical University, Graduate School of Medicine, Sapporo (Japan)
  5. Division of Preventive Medicine, Department of Community Health and Medicine, Research Institute, International Medical Center of Japan, Tokyo (Japan)
  6. Radiation Oncology Division, National Cancer Center Hospital East, Kashiwa (Japan)
Publication Date:
OSTI Identifier:
20951660
Resource Type:
Journal Article
Resource Relation:
Journal Name: International Journal of Radiation Oncology, Biology and Physics; Journal Volume: 68; Journal Issue: 2; Other Information: DOI: 10.1016/j.ijrobp.2006.12.012; PII: S0360-3016(06)03652-2; Copyright (c) 2007 Elsevier Science B.V., Amsterdam, Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALGORITHMS; CARCINOMAS; LUNGS; PLANNING; RADIATION DOSES; RADIOTHERAPY

Citation Formats

Matsuo, Yukinori, Takayama, Kenji, Nagata, Yasushi, Kunieda, Etsuo, Tateoka, Kunihiko, Ishizuka, Naoki, Mizowaki, Takashi, Norihisa, Yoshiki, Sakamoto, Masato, Narita, Yuichiro, Ishikura, Satoshi, and Hiraoka, Masahiro. Interinstitutional Variations in Planning for Stereotactic Body Radiation Therapy for Lung Cancer. United States: N. p., 2007. Web. doi:10.1016/j.ijrobp.2006.12.012.
Matsuo, Yukinori, Takayama, Kenji, Nagata, Yasushi, Kunieda, Etsuo, Tateoka, Kunihiko, Ishizuka, Naoki, Mizowaki, Takashi, Norihisa, Yoshiki, Sakamoto, Masato, Narita, Yuichiro, Ishikura, Satoshi, & Hiraoka, Masahiro. Interinstitutional Variations in Planning for Stereotactic Body Radiation Therapy for Lung Cancer. United States. doi:10.1016/j.ijrobp.2006.12.012.
Matsuo, Yukinori, Takayama, Kenji, Nagata, Yasushi, Kunieda, Etsuo, Tateoka, Kunihiko, Ishizuka, Naoki, Mizowaki, Takashi, Norihisa, Yoshiki, Sakamoto, Masato, Narita, Yuichiro, Ishikura, Satoshi, and Hiraoka, Masahiro. Fri . "Interinstitutional Variations in Planning for Stereotactic Body Radiation Therapy for Lung Cancer". United States. doi:10.1016/j.ijrobp.2006.12.012.
@article{osti_20951660,
title = {Interinstitutional Variations in Planning for Stereotactic Body Radiation Therapy for Lung Cancer},
author = {Matsuo, Yukinori and Takayama, Kenji and Nagata, Yasushi and Kunieda, Etsuo and Tateoka, Kunihiko and Ishizuka, Naoki and Mizowaki, Takashi and Norihisa, Yoshiki and Sakamoto, Masato and Narita, Yuichiro and Ishikura, Satoshi and Hiraoka, Masahiro},
abstractNote = {Purpose: The aim of this study was to assess interinstitutional variations in planning for stereotactic body radiation therapy (SBRT) for lung cancer before the start of the Japan Clinical Oncology Group (JCOG) 0403 trial. Methods and Materials: Eleven institutions created virtual plans for four cases of solitary lung cancer. The created plans should satisfy the target definitions and the dose constraints for the JCOG 0403 protocol. Results: FOCUS/XiO (CMS) was used in six institutions, Eclipse (Varian) in 3, Cadplan (Varian) in one, and Pinnacle3 (Philips/ADAC) in one. Dose calculation algorithms of Clarkson with effective path length correction and superposition were used in FOCUS/XiO; pencil beam convolution with Batho power law correction was used in Eclipse and Cadplan; and collapsed cone convolution superposition was used in Pinnacle3. For the target volumes, the overall coefficient of variation was 16.6%, and the interinstitutional variations were not significant. For maximal dose, minimal dose, D95, and the homogeneity index of the planning target volume, the interinstitutional variations were significant. The dose calculation algorithm was a significant factor in these variations. No violation of the dose constraints for the protocol was observed. Conclusion: There can be notable interinstitutional variations in planning for SBRT, including both interobserver variations in the estimate of target volumes as well as dose calculation effects related to the use of different dose calculation algorithms.},
doi = {10.1016/j.ijrobp.2006.12.012},
journal = {International Journal of Radiation Oncology, Biology and Physics},
number = 2,
volume = 68,
place = {United States},
year = {Fri Jun 01 00:00:00 EDT 2007},
month = {Fri Jun 01 00:00:00 EDT 2007}
}