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Title: The multi-module, multi-resolution system (M{sup 3}R): A novel small-animal SPECT system

Abstract

We have designed and built an inexpensive, high-resolution, tomographic imaging system, dubbed the multi-module, multi-resolution system, or M{sup 3}R. Slots machined into the system shielding allow for the interchange of pinhole plates, enabling the system to operate over a wide range of magnifications and with virtually any desired pinhole configuration. The flexibility of the system allows system optimization for specific imaging tasks and also allows for modifications necessary due to improved detectors, electronics, and knowledge of system construction (e.g., system sensitivity optimization). We provide an overview of M{sup 3}R, focusing primarily on system design and construction, aperture construction, and calibration methods. Reconstruction algorithms will be described and reconstructed images presented.

Authors:
; ; ; ;  [1];  [2];  [2];  [2]
  1. College of Optical Sciences, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721 (United States)
  2. (United States)
Publication Date:
OSTI Identifier:
20951112
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 34; Journal Issue: 3; Other Information: DOI: 10.1118/1.2432071; (c) 2007 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALGORITHMS; APERTURES; CALIBRATION; FLEXIBILITY; IMAGE PROCESSING; IMAGES; OPTIMIZATION; SENSITIVITY; SHIELDING; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SPATIAL RESOLUTION

Citation Formats

Hesterman, Jacob Y., Kupinski, Matthew A., Furenlid, Lars R., Wilson, Donald W., Barrett, Harrison H., College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721, Department of Radiology, University of Arizona, 1609 N. Warren Ave., Bldg 211, Tucson, Arizona 85724, and College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721. The multi-module, multi-resolution system (M{sup 3}R): A novel small-animal SPECT system. United States: N. p., 2007. Web. doi:10.1118/1.2432071.
Hesterman, Jacob Y., Kupinski, Matthew A., Furenlid, Lars R., Wilson, Donald W., Barrett, Harrison H., College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721, Department of Radiology, University of Arizona, 1609 N. Warren Ave., Bldg 211, Tucson, Arizona 85724, & College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721. The multi-module, multi-resolution system (M{sup 3}R): A novel small-animal SPECT system. United States. doi:10.1118/1.2432071.
Hesterman, Jacob Y., Kupinski, Matthew A., Furenlid, Lars R., Wilson, Donald W., Barrett, Harrison H., College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721, Department of Radiology, University of Arizona, 1609 N. Warren Ave., Bldg 211, Tucson, Arizona 85724, and College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721. Thu . "The multi-module, multi-resolution system (M{sup 3}R): A novel small-animal SPECT system". United States. doi:10.1118/1.2432071.
@article{osti_20951112,
title = {The multi-module, multi-resolution system (M{sup 3}R): A novel small-animal SPECT system},
author = {Hesterman, Jacob Y. and Kupinski, Matthew A. and Furenlid, Lars R. and Wilson, Donald W. and Barrett, Harrison H. and College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721 and Department of Radiology, University of Arizona, 1609 N. Warren Ave., Bldg 211, Tucson, Arizona 85724 and College of Optical Sciences and Department of Radiology, University of Arizona, 1630 E. University Blvd., Tucson, Arizona 85721},
abstractNote = {We have designed and built an inexpensive, high-resolution, tomographic imaging system, dubbed the multi-module, multi-resolution system, or M{sup 3}R. Slots machined into the system shielding allow for the interchange of pinhole plates, enabling the system to operate over a wide range of magnifications and with virtually any desired pinhole configuration. The flexibility of the system allows system optimization for specific imaging tasks and also allows for modifications necessary due to improved detectors, electronics, and knowledge of system construction (e.g., system sensitivity optimization). We provide an overview of M{sup 3}R, focusing primarily on system design and construction, aperture construction, and calibration methods. Reconstruction algorithms will be described and reconstructed images presented.},
doi = {10.1118/1.2432071},
journal = {Medical Physics},
number = 3,
volume = 34,
place = {United States},
year = {Thu Mar 15 00:00:00 EDT 2007},
month = {Thu Mar 15 00:00:00 EDT 2007}
}