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Title: A 4x500 mm{sup 2} cloverleaf detector system for in vivo bone lead measurement

Abstract

A 4x500 mm{sup 2} 'cloverleaf' low energy germanium detector array has been assembled for the purpose of in vivo bone lead measurement through x-ray fluorescence. Using {sup 109}Cd as an exciting source, results are reported from a leg phantom simulating measurement of lead in a human tibia. For high activity (4.0-4.4 GBq) and low activity (0.18-0.19 GBq) sources, measurement results are reported for both the cloverleaf system and a conventional single detector system of equivalent surface area (2000 mm{sup 2}). The mean uncertainty and reproducibility of measurement were both significantly improved for the cloverleaf system with a high activity {sup 109}Cd source. When using a source activity of 4.4 GBq, measurement of the phantom resulted in an average bone lead uncertainty of 0.79 {mu}g/g and a reproducibility of 0.84 {mu}g/g. These results represent the highest precision yet reported from a bone lead x-ray fluorescence system.

Authors:
;  [1]
  1. Department of Physics, Mount Allison University, 67 York Street, Sackville, New Brunswick, E4L 1E6 (Canada)
Publication Date:
OSTI Identifier:
20951107
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 34; Journal Issue: 3; Other Information: DOI: 10.1118/1.2436973; (c) 2007 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; CADMIUM 109; FLUORESCENCE; GE SEMICONDUCTOR DETECTORS; IN VIVO; LEAD; PHANTOMS; SURFACE AREA; TIBIA; X-RAY FLUORESCENCE ANALYSIS

Citation Formats

Fleming, David E. B., and Mills, Caitlin E. A 4x500 mm{sup 2} cloverleaf detector system for in vivo bone lead measurement. United States: N. p., 2007. Web. doi:10.1118/1.2436973.
Fleming, David E. B., & Mills, Caitlin E. A 4x500 mm{sup 2} cloverleaf detector system for in vivo bone lead measurement. United States. doi:10.1118/1.2436973.
Fleming, David E. B., and Mills, Caitlin E. Thu . "A 4x500 mm{sup 2} cloverleaf detector system for in vivo bone lead measurement". United States. doi:10.1118/1.2436973.
@article{osti_20951107,
title = {A 4x500 mm{sup 2} cloverleaf detector system for in vivo bone lead measurement},
author = {Fleming, David E. B. and Mills, Caitlin E.},
abstractNote = {A 4x500 mm{sup 2} 'cloverleaf' low energy germanium detector array has been assembled for the purpose of in vivo bone lead measurement through x-ray fluorescence. Using {sup 109}Cd as an exciting source, results are reported from a leg phantom simulating measurement of lead in a human tibia. For high activity (4.0-4.4 GBq) and low activity (0.18-0.19 GBq) sources, measurement results are reported for both the cloverleaf system and a conventional single detector system of equivalent surface area (2000 mm{sup 2}). The mean uncertainty and reproducibility of measurement were both significantly improved for the cloverleaf system with a high activity {sup 109}Cd source. When using a source activity of 4.4 GBq, measurement of the phantom resulted in an average bone lead uncertainty of 0.79 {mu}g/g and a reproducibility of 0.84 {mu}g/g. These results represent the highest precision yet reported from a bone lead x-ray fluorescence system.},
doi = {10.1118/1.2436973},
journal = {Medical Physics},
number = 3,
volume = 34,
place = {United States},
year = {Thu Mar 15 00:00:00 EDT 2007},
month = {Thu Mar 15 00:00:00 EDT 2007}
}