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Title: Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors

Abstract

Application of a single fraction of parallel opposed GRID beams as a means of increasing the efficiency of radiation delivery to deep-seated tumors has been investigated. This evaluation was performed by measurement of dosimetric characteristics of the GRID radiation field in parallel opposed and single beam geometry. The limitations of the parallel opposed technique in terms of field size and tumor thickness have been evaluated for the conditions of acceptable spatial modulation. The results of this investigation have demonstrated an increase in therapeutic advantage for the parallel opposed technique over the single beam method when treating a deep seated tumor.

Authors:
; ; ; ; ;  [1]
  1. Department of Radiation Medicine, University of Kentucky Medical Center, Lexington, Kentucky 40536 (United States)
Publication Date:
OSTI Identifier:
20951052
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 34; Journal Issue: 2; Other Information: DOI: 10.1118/1.2431423; (c) 2007 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BEAMS; DOSIMETRY; EVALUATION; MODULATION; NEOPLASMS; RADIOTHERAPY; THICKNESS

Citation Formats

Meigooni, Ali S., Gnaster, Michael, Dou, Kai, Johnson, Ellis L., Meigooni, Navid J., and Kudrimoti, Mahesh. Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors. United States: N. p., 2007. Web. doi:10.1118/1.2431423.
Meigooni, Ali S., Gnaster, Michael, Dou, Kai, Johnson, Ellis L., Meigooni, Navid J., & Kudrimoti, Mahesh. Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors. United States. doi:10.1118/1.2431423.
Meigooni, Ali S., Gnaster, Michael, Dou, Kai, Johnson, Ellis L., Meigooni, Navid J., and Kudrimoti, Mahesh. Thu . "Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors". United States. doi:10.1118/1.2431423.
@article{osti_20951052,
title = {Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors},
author = {Meigooni, Ali S. and Gnaster, Michael and Dou, Kai and Johnson, Ellis L. and Meigooni, Navid J. and Kudrimoti, Mahesh},
abstractNote = {Application of a single fraction of parallel opposed GRID beams as a means of increasing the efficiency of radiation delivery to deep-seated tumors has been investigated. This evaluation was performed by measurement of dosimetric characteristics of the GRID radiation field in parallel opposed and single beam geometry. The limitations of the parallel opposed technique in terms of field size and tumor thickness have been evaluated for the conditions of acceptable spatial modulation. The results of this investigation have demonstrated an increase in therapeutic advantage for the parallel opposed technique over the single beam method when treating a deep seated tumor.},
doi = {10.1118/1.2431423},
journal = {Medical Physics},
number = 2,
volume = 34,
place = {United States},
year = {Thu Feb 15 00:00:00 EST 2007},
month = {Thu Feb 15 00:00:00 EST 2007}
}