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Title: Efficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer

Abstract

Objective: To evaluate the results of combined decongestive therapy and manual lymphatic drainage in patients with breast cancer-related lymphedema. Methods and Materials: The data from 250 patients were reviewed. The pre- and posttreatment volumetric measurements were compared, and the correlation with age, body mass index, and type of surgery, chemotherapy, and radiotherapy was determined. The Spearman correlation coefficients and Wilcoxon two-sample test were used for statistical analysis. Results: Of the 250 patients, 138 were included in the final analysis. The mean age at presentation was 54.3 years. Patients were stratified on the basis of the treatment modality used for breast cancer management. Lymphedema was managed with combined decongestive therapy in 55%, manual lymphatic drainage alone in 32%, and the home program in 13%. The mean pretreatment volume of the affected and normal arms was 2929 and 2531 mL. At the end of 1 year, the posttreatment volume of the affected arm was 2741 mL. The absolute volume of the affected arm was reduced by a mean of 188 mL (p < 0.0001). The type of surgery (p = 0.0142), age (p = 0.0354), and body mass index (p < 0.0001) were related to the severity of lymphedema. Conclusion: Combined decongestivemore » therapy and manual lymphatic drainage with exercises were associated with a significant reduction in the lymphedema volume.« less

Authors:
 [1];  [2];  [3];  [3];  [4];  [4];  [2]
  1. Department of Radiation Oncology, CancerCare Manitoba, Winnipeg, MB (Canada). E-mail: rashmi.koul@cancercare.mb.ca
  2. Department of Radiation Oncology, CancerCare Manitoba, Winnipeg, MB (Canada)
  3. Winnipeg Regional Health Authority Breast Health Center, Winnipeg, MB (Canada)
  4. Epidemiology and Cancer Registry, CancerCare Manitoba, Winnipeg, MB (Canada)
Publication Date:
OSTI Identifier:
20944737
Resource Type:
Journal Article
Resource Relation:
Journal Name: International Journal of Radiation Oncology, Biology and Physics; Journal Volume: 67; Journal Issue: 3; Other Information: DOI: 10.1016/j.ijrobp.2006.09.024; PII: S0360-3016(06)02997-X; Copyright (c) 2007 Elsevier Science B.V., Amsterdam, Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; CHEMOTHERAPY; MAMMARY GLANDS; MANUALS; PATIENTS; RADIOTHERAPY; SURGERY

Citation Formats

Koul, Rashmi, Dufan, Tarek, Russell, Catherine, Guenther, Wanda, Nugent, Zoan, Sun Xuyan, and Cooke, Andrew L. Efficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer. United States: N. p., 2007. Web. doi:10.1016/j.ijrobp.2006.09.024.
Koul, Rashmi, Dufan, Tarek, Russell, Catherine, Guenther, Wanda, Nugent, Zoan, Sun Xuyan, & Cooke, Andrew L. Efficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer. United States. doi:10.1016/j.ijrobp.2006.09.024.
Koul, Rashmi, Dufan, Tarek, Russell, Catherine, Guenther, Wanda, Nugent, Zoan, Sun Xuyan, and Cooke, Andrew L. Thu . "Efficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer". United States. doi:10.1016/j.ijrobp.2006.09.024.
@article{osti_20944737,
title = {Efficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer},
author = {Koul, Rashmi and Dufan, Tarek and Russell, Catherine and Guenther, Wanda and Nugent, Zoan and Sun Xuyan and Cooke, Andrew L.},
abstractNote = {Objective: To evaluate the results of combined decongestive therapy and manual lymphatic drainage in patients with breast cancer-related lymphedema. Methods and Materials: The data from 250 patients were reviewed. The pre- and posttreatment volumetric measurements were compared, and the correlation with age, body mass index, and type of surgery, chemotherapy, and radiotherapy was determined. The Spearman correlation coefficients and Wilcoxon two-sample test were used for statistical analysis. Results: Of the 250 patients, 138 were included in the final analysis. The mean age at presentation was 54.3 years. Patients were stratified on the basis of the treatment modality used for breast cancer management. Lymphedema was managed with combined decongestive therapy in 55%, manual lymphatic drainage alone in 32%, and the home program in 13%. The mean pretreatment volume of the affected and normal arms was 2929 and 2531 mL. At the end of 1 year, the posttreatment volume of the affected arm was 2741 mL. The absolute volume of the affected arm was reduced by a mean of 188 mL (p < 0.0001). The type of surgery (p = 0.0142), age (p = 0.0354), and body mass index (p < 0.0001) were related to the severity of lymphedema. Conclusion: Combined decongestive therapy and manual lymphatic drainage with exercises were associated with a significant reduction in the lymphedema volume.},
doi = {10.1016/j.ijrobp.2006.09.024},
journal = {International Journal of Radiation Oncology, Biology and Physics},
number = 3,
volume = 67,
place = {United States},
year = {Thu Mar 01 00:00:00 EST 2007},
month = {Thu Mar 01 00:00:00 EST 2007}
}