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Title: Protein destruction by atmospheric pressure glow discharges

Abstract

It is well established that atmospheric pressure glow discharges are capable of bacterial inactivation. Much less known is their ability to destruct infectious proteins, even though surgical instruments are often contaminated by both bacteria and proteinaceous matters. In this letter, the authors present a study of protein destruction using a low-temperature atmospheric dielectric-barrier discharge jet. Clear evidences of protein removal are presented with data of several complimentary experiments using scanning electron microscopy, electron dispersive x-ray analysis, electrophoresis, laser-induced fluorescence microscopy, and protein reduction kinetics. Considerable degradation is observed of protein fragments that remain on their substrate surface after plasma treatment.

Authors:
; ; ;  [1];  [2];  [2]
  1. Department of Electronic and Electrical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom)
  2. (United Kingdom)
Publication Date:
OSTI Identifier:
20883259
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 90; Journal Issue: 1; Other Information: DOI: 10.1063/1.2410219; (c) 2007 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; ATMOSPHERIC PRESSURE; BACTERIA; BIOLOGICAL RADIATION EFFECTS; CHEMICAL ANALYSIS; DIELECTRIC MATERIALS; ELECTROPHORESIS; FLUORESCENCE; GLOW DISCHARGES; OPTICAL MICROSCOPY; PLASMA JETS; PROTEINS; SCANNING ELECTRON MICROSCOPY; X RADIATION

Citation Formats

Deng, X. T., Shi, J. J., Chen, H. L., Kong, M. G., MRC Toxicology Unit, University of Leicester, Leicester, Leicestershire LE1 9HN, and Department of Electronic and Electrical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU. Protein destruction by atmospheric pressure glow discharges. United States: N. p., 2007. Web. doi:10.1063/1.2410219.
Deng, X. T., Shi, J. J., Chen, H. L., Kong, M. G., MRC Toxicology Unit, University of Leicester, Leicester, Leicestershire LE1 9HN, & Department of Electronic and Electrical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU. Protein destruction by atmospheric pressure glow discharges. United States. doi:10.1063/1.2410219.
Deng, X. T., Shi, J. J., Chen, H. L., Kong, M. G., MRC Toxicology Unit, University of Leicester, Leicester, Leicestershire LE1 9HN, and Department of Electronic and Electrical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU. Mon . "Protein destruction by atmospheric pressure glow discharges". United States. doi:10.1063/1.2410219.
@article{osti_20883259,
title = {Protein destruction by atmospheric pressure glow discharges},
author = {Deng, X. T. and Shi, J. J. and Chen, H. L. and Kong, M. G. and MRC Toxicology Unit, University of Leicester, Leicester, Leicestershire LE1 9HN and Department of Electronic and Electrical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU},
abstractNote = {It is well established that atmospheric pressure glow discharges are capable of bacterial inactivation. Much less known is their ability to destruct infectious proteins, even though surgical instruments are often contaminated by both bacteria and proteinaceous matters. In this letter, the authors present a study of protein destruction using a low-temperature atmospheric dielectric-barrier discharge jet. Clear evidences of protein removal are presented with data of several complimentary experiments using scanning electron microscopy, electron dispersive x-ray analysis, electrophoresis, laser-induced fluorescence microscopy, and protein reduction kinetics. Considerable degradation is observed of protein fragments that remain on their substrate surface after plasma treatment.},
doi = {10.1063/1.2410219},
journal = {Applied Physics Letters},
number = 1,
volume = 90,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2007},
month = {Mon Jan 01 00:00:00 EST 2007}
}