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Title: Evaluating the impact of x-ray spectral shape on image quality in flat-panel CT breast imaging

Abstract

In recent years, there has been an increasing interest in exploring the feasibility of dedicated computed tomography (CT) breast imaging using a flat-panel digital detector in a truncated cone-beam imaging geometry. Preliminary results are promising and it appears as if three-dimensional tomographic imaging of the breast has great potential for reducing the masking effect of superimposed parenchymal structure typically observed with conventional mammography. In this study, a mathematical framework used for determining optimal design and acquisition parameters for such a CT breast imaging system is described. The ideal observer signal-to-noise ratio (SNR) is used as a figure of merit, under the assumptions that the imaging system is linear and shift invariant. Computation of the ideal observer SNR used a parallel-cascade model to predict signal and noise propagation through the detector, as well as a realistic model of the lesion detection task in breast imaging. For all evaluations, the total mean glandular dose for a CT breast imaging study was constrained to be approximately equivalent to that of a two-view conventional mammography study. The framework presented was used to explore the effect of x-ray spectral shape across an extensive range of kVp settings, filter material types, and filter thicknesses. The resultsmore » give an indication of how spectral shape can affect image quality in flat-panel CT breast imaging.« less

Authors:
; ; ;  [1];  [2];  [2];  [2]
  1. Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655 (United States)
  2. (United States)
Publication Date:
OSTI Identifier:
20853934
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 34; Journal Issue: 1; Other Information: DOI: 10.1118/1.2388574; (c) 2007 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOMEDICAL RADIOGRAPHY; CARCINOMAS; COMPUTERIZED TOMOGRAPHY; EVALUATION; GYNECOLOGY; IMAGE PROCESSING; IMAGES; MAMMARY GLANDS; PERFORMANCE; SIGNAL-TO-NOISE RATIO; X RADIATION

Citation Formats

Glick, Stephen J., Thacker, Samta, Gong Xing, Liu, Bob, Radiation Monitoring Devices, Inc., 44 Hunt Street, Watertown, Massachusetts 02172, Department of Medical Physics and Radiation Oncology, Rush University Medical Center, Chicago, Illinois, 60612, and Massachusetts General Hospital, Boston, Massachusetts 02114. Evaluating the impact of x-ray spectral shape on image quality in flat-panel CT breast imaging. United States: N. p., 2007. Web. doi:10.1118/1.2388574.
Glick, Stephen J., Thacker, Samta, Gong Xing, Liu, Bob, Radiation Monitoring Devices, Inc., 44 Hunt Street, Watertown, Massachusetts 02172, Department of Medical Physics and Radiation Oncology, Rush University Medical Center, Chicago, Illinois, 60612, & Massachusetts General Hospital, Boston, Massachusetts 02114. Evaluating the impact of x-ray spectral shape on image quality in flat-panel CT breast imaging. United States. doi:10.1118/1.2388574.
Glick, Stephen J., Thacker, Samta, Gong Xing, Liu, Bob, Radiation Monitoring Devices, Inc., 44 Hunt Street, Watertown, Massachusetts 02172, Department of Medical Physics and Radiation Oncology, Rush University Medical Center, Chicago, Illinois, 60612, and Massachusetts General Hospital, Boston, Massachusetts 02114. Mon . "Evaluating the impact of x-ray spectral shape on image quality in flat-panel CT breast imaging". United States. doi:10.1118/1.2388574.
@article{osti_20853934,
title = {Evaluating the impact of x-ray spectral shape on image quality in flat-panel CT breast imaging},
author = {Glick, Stephen J. and Thacker, Samta and Gong Xing and Liu, Bob and Radiation Monitoring Devices, Inc., 44 Hunt Street, Watertown, Massachusetts 02172 and Department of Medical Physics and Radiation Oncology, Rush University Medical Center, Chicago, Illinois, 60612 and Massachusetts General Hospital, Boston, Massachusetts 02114},
abstractNote = {In recent years, there has been an increasing interest in exploring the feasibility of dedicated computed tomography (CT) breast imaging using a flat-panel digital detector in a truncated cone-beam imaging geometry. Preliminary results are promising and it appears as if three-dimensional tomographic imaging of the breast has great potential for reducing the masking effect of superimposed parenchymal structure typically observed with conventional mammography. In this study, a mathematical framework used for determining optimal design and acquisition parameters for such a CT breast imaging system is described. The ideal observer signal-to-noise ratio (SNR) is used as a figure of merit, under the assumptions that the imaging system is linear and shift invariant. Computation of the ideal observer SNR used a parallel-cascade model to predict signal and noise propagation through the detector, as well as a realistic model of the lesion detection task in breast imaging. For all evaluations, the total mean glandular dose for a CT breast imaging study was constrained to be approximately equivalent to that of a two-view conventional mammography study. The framework presented was used to explore the effect of x-ray spectral shape across an extensive range of kVp settings, filter material types, and filter thicknesses. The results give an indication of how spectral shape can affect image quality in flat-panel CT breast imaging.},
doi = {10.1118/1.2388574},
journal = {Medical Physics},
number = 1,
volume = 34,
place = {United States},
year = {Mon Jan 15 00:00:00 EST 2007},
month = {Mon Jan 15 00:00:00 EST 2007}
}