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Title: Ultrasound-Stimulated Acoustic Emission in Thermal Image-Guided HIFU Therapy: A Phantom Study

Abstract

Magnetic resonance image (MRI) is a promising monitoring tool for non-invasive real-time thermal guidance in high intensity focused ultrasound (HIFU) during thermal ablation surgery. However, this approach has two main drawbacks: 1) majority of components need to be redesigned to be MR compatible in order to avoid effecting MR images, and 2) the cost of operating MRI facilities is high. Alternately, ultrasound-stimulated acoustic emission (USAE) method has been applied for detecting thermal variations in tissues. An optical transparent phantom, made from polyacrylamide, containing thermal sensitive indicator protein (Bovine Serum Albumin), was prepared for observing the HIFU-induced denaturalization. A thermal-couple was set up for validation of temperature distribution. Experimental results show that thermal image can be captured clearly under stationary conditions.

Authors:
;  [1];  [2]
  1. Biomedical Engineering Center, Industrial Technology Research Institute, Hsinchu, Taiwan (China)
  2. Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan (China)
Publication Date:
OSTI Identifier:
20800254
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 829; Journal Issue: 1; Conference: 5. international symposium on therapeutic ultrasound, Boston, MA (United States), 27-29 Oct 2005; Other Information: DOI: 10.1063/1.2205454; (c) 2006 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; ABLATION; ALBUMINS; EMISSION; IMAGES; MONITORING; NMR IMAGING; NUCLEAR MAGNETIC RESONANCE; RADIOTHERAPY; SURGERY; TEMPERATURE DISTRIBUTION; ULTRASONOGRAPHY; VALIDATION; VARIATIONS

Citation Formats

Jiang, C. P., Lin, W. T., and Chen, W. S. Ultrasound-Stimulated Acoustic Emission in Thermal Image-Guided HIFU Therapy: A Phantom Study. United States: N. p., 2006. Web. doi:10.1063/1.2205454.
Jiang, C. P., Lin, W. T., & Chen, W. S. Ultrasound-Stimulated Acoustic Emission in Thermal Image-Guided HIFU Therapy: A Phantom Study. United States. doi:10.1063/1.2205454.
Jiang, C. P., Lin, W. T., and Chen, W. S. Mon . "Ultrasound-Stimulated Acoustic Emission in Thermal Image-Guided HIFU Therapy: A Phantom Study". United States. doi:10.1063/1.2205454.
@article{osti_20800254,
title = {Ultrasound-Stimulated Acoustic Emission in Thermal Image-Guided HIFU Therapy: A Phantom Study},
author = {Jiang, C. P. and Lin, W. T. and Chen, W. S.},
abstractNote = {Magnetic resonance image (MRI) is a promising monitoring tool for non-invasive real-time thermal guidance in high intensity focused ultrasound (HIFU) during thermal ablation surgery. However, this approach has two main drawbacks: 1) majority of components need to be redesigned to be MR compatible in order to avoid effecting MR images, and 2) the cost of operating MRI facilities is high. Alternately, ultrasound-stimulated acoustic emission (USAE) method has been applied for detecting thermal variations in tissues. An optical transparent phantom, made from polyacrylamide, containing thermal sensitive indicator protein (Bovine Serum Albumin), was prepared for observing the HIFU-induced denaturalization. A thermal-couple was set up for validation of temperature distribution. Experimental results show that thermal image can be captured clearly under stationary conditions.},
doi = {10.1063/1.2205454},
journal = {AIP Conference Proceedings},
number = 1,
volume = 829,
place = {United States},
year = {Mon May 08 00:00:00 EDT 2006},
month = {Mon May 08 00:00:00 EDT 2006}
}