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Title: Patient tolerance of rectal balloons in conformal radiation treatment of prostate cancer

Abstract

Purpose: To evaluate patient tolerance of intrarectal balloons used during conformal prostate irradiation. Methods and Materials: A retrospective analysis was performed on 3,561 patients who underwent conformal radiation for prostate cancer. Therapy consisted of proton irradiation of the prostate and seminal vesicles and X-ray treatment of the pelvis when warranted. The number of treatments in which the balloon was tolerated was recorded. Results were stratified according to method of irradiation (protons alone vs. combined proton/X-ray) and method of planning (2D vs. 3D planning of X-ray fields in patients undergoing combination treatment). Results: Of all the patients evaluated, 3,474 (97.6%) tolerated the balloon throughout treatment; 87 (2.4%) declined the balloon for 1 or more treatments and tolerated the balloon for 85.5% of their treatments. Chi-square analysis revealed a significant tolerance advantage in those who received protons alone compared with combination treatment (99.5% vs. 95.7%; p < 0.001). In patients undergoing combination treatment, chi-square analysis did not reveal significant tolerance differences in patients undergoing 3D vs. 2D planning for pelvic X-ray fields (95.74% vs. 95.72%; p = 0.990). Conclusions: Intrarectal balloons are well tolerated over a course of conformal prostate irradiation.

Authors:
 [1];  [1];  [1];  [1];  [2]
  1. Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, CA (United States)
  2. Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, CA (United States). E-mail: jdslater@dominion.llumc.edu
Publication Date:
OSTI Identifier:
20793420
Resource Type:
Journal Article
Resource Relation:
Journal Name: International Journal of Radiation Oncology, Biology and Physics; Journal Volume: 64; Journal Issue: 5; Other Information: DOI: 10.1016/j.ijrobp.2005.11.001; PII: S0360-3016(05)02866-X; Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; IRRADIATION; NEOPLASMS; PATIENTS; PELVIS; PLANNING; PROSTATE; PROTON BEAMS; RADIOTHERAPY; TOLERANCE; X RADIATION

Citation Formats

Ronson, Brian B., Yonemoto, Les T., Rossi, Carl J., Slater, James M., and Slater, Jerry D. Patient tolerance of rectal balloons in conformal radiation treatment of prostate cancer. United States: N. p., 2006. Web. doi:10.1016/J.IJROBP.2005.1.
Ronson, Brian B., Yonemoto, Les T., Rossi, Carl J., Slater, James M., & Slater, Jerry D. Patient tolerance of rectal balloons in conformal radiation treatment of prostate cancer. United States. doi:10.1016/J.IJROBP.2005.1.
Ronson, Brian B., Yonemoto, Les T., Rossi, Carl J., Slater, James M., and Slater, Jerry D. Sat . "Patient tolerance of rectal balloons in conformal radiation treatment of prostate cancer". United States. doi:10.1016/J.IJROBP.2005.1.
@article{osti_20793420,
title = {Patient tolerance of rectal balloons in conformal radiation treatment of prostate cancer},
author = {Ronson, Brian B. and Yonemoto, Les T. and Rossi, Carl J. and Slater, James M. and Slater, Jerry D.},
abstractNote = {Purpose: To evaluate patient tolerance of intrarectal balloons used during conformal prostate irradiation. Methods and Materials: A retrospective analysis was performed on 3,561 patients who underwent conformal radiation for prostate cancer. Therapy consisted of proton irradiation of the prostate and seminal vesicles and X-ray treatment of the pelvis when warranted. The number of treatments in which the balloon was tolerated was recorded. Results were stratified according to method of irradiation (protons alone vs. combined proton/X-ray) and method of planning (2D vs. 3D planning of X-ray fields in patients undergoing combination treatment). Results: Of all the patients evaluated, 3,474 (97.6%) tolerated the balloon throughout treatment; 87 (2.4%) declined the balloon for 1 or more treatments and tolerated the balloon for 85.5% of their treatments. Chi-square analysis revealed a significant tolerance advantage in those who received protons alone compared with combination treatment (99.5% vs. 95.7%; p < 0.001). In patients undergoing combination treatment, chi-square analysis did not reveal significant tolerance differences in patients undergoing 3D vs. 2D planning for pelvic X-ray fields (95.74% vs. 95.72%; p = 0.990). Conclusions: Intrarectal balloons are well tolerated over a course of conformal prostate irradiation.},
doi = {10.1016/J.IJROBP.2005.1},
journal = {International Journal of Radiation Oncology, Biology and Physics},
number = 5,
volume = 64,
place = {United States},
year = {Sat Apr 01 00:00:00 EST 2006},
month = {Sat Apr 01 00:00:00 EST 2006}
}