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Title: Medical application of radioactive nuclear beams at HIMAC

Abstract

By using the radioactive nuclear beam with relativistic high energy of short-lived positron emitting nuclei, such as {sup 10}C and {sup 11}C, a verification system for the precise radiotherapy has been developed. It is possible to determine the precise particle range and the three-dimensional irradiated area in the human body by a positron camera detector and a positron emission tomography system, respectively. The biological and chemical process of the metabolism is an important parameter for the precise measurement. The biological lifetimes of the {sup 10}C and {sup 11}C injected into the rabbit's organs have been observed for the study of metabolism. The microscopic process around the cell is also of interest in the study of biological effectiveness. The observation of the difference between radiological effectiveness of {sup 9}C and that of {sup 12}C is in progress.

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ; ;  [1];  [2];  [3]
  1. National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan)
  2. (China)
  3. (Japan)
Publication Date:
OSTI Identifier:
20779098
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 77; Journal Issue: 3; Conference: 11. international conference on ion sources, Caen (France), 12-16 Sep 2005; Other Information: DOI: 10.1063/1.2149309; (c) 2006 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; BEAMS; BIOPHYSICS; CARBON 10; CARBON 11; CARBON 12; CARBON 9; IRRADIATION; METABOLISM; ORGANS; POSITRON CAMERAS; POSITRON COMPUTED TOMOGRAPHY; POSITRONS; RABBITS; RADIOTHERAPY; RELATIVISTIC RANGE

Citation Formats

Kitagawa, A., Furusawa, Y., Kanai, T., Kanazawa, M., Mizuno, H., Muramatsu, M., Sato, S., Suda, M., Tomitani, T., Urakabe, E., Yoshimoto, M., Li, Q., Wei, Z., Hanawa, K., Iseki, Y., Sato, K., Institute of Modern Physics, Chinese Academy of Science, P.O. Box 31, Lanzhou 730000, and Toshiba Corp., 1 Toshiba-cho, Fuchu 183-8511. Medical application of radioactive nuclear beams at HIMAC. United States: N. p., 2006. Web. doi:10.1063/1.2149309.
Kitagawa, A., Furusawa, Y., Kanai, T., Kanazawa, M., Mizuno, H., Muramatsu, M., Sato, S., Suda, M., Tomitani, T., Urakabe, E., Yoshimoto, M., Li, Q., Wei, Z., Hanawa, K., Iseki, Y., Sato, K., Institute of Modern Physics, Chinese Academy of Science, P.O. Box 31, Lanzhou 730000, & Toshiba Corp., 1 Toshiba-cho, Fuchu 183-8511. Medical application of radioactive nuclear beams at HIMAC. United States. doi:10.1063/1.2149309.
Kitagawa, A., Furusawa, Y., Kanai, T., Kanazawa, M., Mizuno, H., Muramatsu, M., Sato, S., Suda, M., Tomitani, T., Urakabe, E., Yoshimoto, M., Li, Q., Wei, Z., Hanawa, K., Iseki, Y., Sato, K., Institute of Modern Physics, Chinese Academy of Science, P.O. Box 31, Lanzhou 730000, and Toshiba Corp., 1 Toshiba-cho, Fuchu 183-8511. Wed . "Medical application of radioactive nuclear beams at HIMAC". United States. doi:10.1063/1.2149309.
@article{osti_20779098,
title = {Medical application of radioactive nuclear beams at HIMAC},
author = {Kitagawa, A. and Furusawa, Y. and Kanai, T. and Kanazawa, M. and Mizuno, H. and Muramatsu, M. and Sato, S. and Suda, M. and Tomitani, T. and Urakabe, E. and Yoshimoto, M. and Li, Q. and Wei, Z. and Hanawa, K. and Iseki, Y. and Sato, K. and Institute of Modern Physics, Chinese Academy of Science, P.O. Box 31, Lanzhou 730000 and Toshiba Corp., 1 Toshiba-cho, Fuchu 183-8511},
abstractNote = {By using the radioactive nuclear beam with relativistic high energy of short-lived positron emitting nuclei, such as {sup 10}C and {sup 11}C, a verification system for the precise radiotherapy has been developed. It is possible to determine the precise particle range and the three-dimensional irradiated area in the human body by a positron camera detector and a positron emission tomography system, respectively. The biological and chemical process of the metabolism is an important parameter for the precise measurement. The biological lifetimes of the {sup 10}C and {sup 11}C injected into the rabbit's organs have been observed for the study of metabolism. The microscopic process around the cell is also of interest in the study of biological effectiveness. The observation of the difference between radiological effectiveness of {sup 9}C and that of {sup 12}C is in progress.},
doi = {10.1063/1.2149309},
journal = {Review of Scientific Instruments},
number = 3,
volume = 77,
place = {United States},
year = {Wed Mar 15 00:00:00 EST 2006},
month = {Wed Mar 15 00:00:00 EST 2006}
}