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Title: Erratum: 'Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility' [Rev. Sci. Instrum. 76, 064303 (2005)]

Abstract

No abstract prepared.

Authors:
; ; ; ; ; ; ; ; ;  [1];  [2];  [2];  [3];  [2];  [3];  [2]
  1. European Synchrotron Radiation Facility, B.P.220, 38043 Grenoble (France)
  2. (Switzerland)
  3. (United States)
Publication Date:
OSTI Identifier:
20778939
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 77; Journal Issue: 3; Other Information: DOI: 10.1063/1.2173954; (c) 2006 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; COLLIMATORS; EUROPEAN SYNCHROTRON RADIATION FACILITY; RADIOTHERAPY; SYNCHROTRON RADIATION; TUNGSTEN

Citation Formats

Braeuer-Krisch, E., Bravin, A., Zhang, L., Siegbahn, E., Stepanek, J., Blattmann, H., Slatkin, D.N., Gebbers, J.-O., Jasmin, M., Laissue, J.A., Unterriedstrasse 33, 5412 Gebenstorf, Niederwiesstrasse 13 C, CH-5427 Untersiggenthal, P.O. Box 334, Essex, Connecticut 06426, Institute of Pathology, Kantonsspital Luzern, 6000 Lucerne, Tecomet Subsidiary, Viasys Healthcare Inc., 170 New Boston Street, Woburn, Massachusetts 01801, and Institute of Pathology, University of Bern, Murtenstrasse 31, 3010 Bern. Erratum: 'Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility' [Rev. Sci. Instrum. 76, 064303 (2005)]. United States: N. p., 2006. Web. doi:10.1063/1.2173954.
Braeuer-Krisch, E., Bravin, A., Zhang, L., Siegbahn, E., Stepanek, J., Blattmann, H., Slatkin, D.N., Gebbers, J.-O., Jasmin, M., Laissue, J.A., Unterriedstrasse 33, 5412 Gebenstorf, Niederwiesstrasse 13 C, CH-5427 Untersiggenthal, P.O. Box 334, Essex, Connecticut 06426, Institute of Pathology, Kantonsspital Luzern, 6000 Lucerne, Tecomet Subsidiary, Viasys Healthcare Inc., 170 New Boston Street, Woburn, Massachusetts 01801, & Institute of Pathology, University of Bern, Murtenstrasse 31, 3010 Bern. Erratum: 'Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility' [Rev. Sci. Instrum. 76, 064303 (2005)]. United States. doi:10.1063/1.2173954.
Braeuer-Krisch, E., Bravin, A., Zhang, L., Siegbahn, E., Stepanek, J., Blattmann, H., Slatkin, D.N., Gebbers, J.-O., Jasmin, M., Laissue, J.A., Unterriedstrasse 33, 5412 Gebenstorf, Niederwiesstrasse 13 C, CH-5427 Untersiggenthal, P.O. Box 334, Essex, Connecticut 06426, Institute of Pathology, Kantonsspital Luzern, 6000 Lucerne, Tecomet Subsidiary, Viasys Healthcare Inc., 170 New Boston Street, Woburn, Massachusetts 01801, and Institute of Pathology, University of Bern, Murtenstrasse 31, 3010 Bern. Wed . "Erratum: 'Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility' [Rev. Sci. Instrum. 76, 064303 (2005)]". United States. doi:10.1063/1.2173954.
@article{osti_20778939,
title = {Erratum: 'Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility' [Rev. Sci. Instrum. 76, 064303 (2005)]},
author = {Braeuer-Krisch, E. and Bravin, A. and Zhang, L. and Siegbahn, E. and Stepanek, J. and Blattmann, H. and Slatkin, D.N. and Gebbers, J.-O. and Jasmin, M. and Laissue, J.A. and Unterriedstrasse 33, 5412 Gebenstorf and Niederwiesstrasse 13 C, CH-5427 Untersiggenthal and P.O. Box 334, Essex, Connecticut 06426 and Institute of Pathology, Kantonsspital Luzern, 6000 Lucerne and Tecomet Subsidiary, Viasys Healthcare Inc., 170 New Boston Street, Woburn, Massachusetts 01801 and Institute of Pathology, University of Bern, Murtenstrasse 31, 3010 Bern},
abstractNote = {No abstract prepared.},
doi = {10.1063/1.2173954},
journal = {Review of Scientific Instruments},
number = 3,
volume = 77,
place = {United States},
year = {Wed Mar 15 00:00:00 EST 2006},
month = {Wed Mar 15 00:00:00 EST 2006}
}
  • Clinical microbeam radiation therapy (MRT) will require a multislit collimator with adjustable uniform slit widths to enable reliable Monte Carlo-based treatment planning. Such a collimator has been designed, fabricated of >99% tungsten [W] by Tecomet/Viasys (Woburn, Massachusetts, USA) and installed at the 6 GeV electron-wiggler-generated hard x-ray ID17 beamline of the European Synchrotron Radiation Facility. Its pair of 125 parallel, 8 mm deep, 0.100 mm wide radiolucent slits, 0.400 mm on center, are perfused with nitrogen gas [N{sub 2}] to dissipate heat during irradiation. Major improvements in uniformity of microbeam widths and good peak/valley dose ratios combined with a verymore » high dose rate in targeted tissues have been achieved.« less
  • We present measurements of the velocity distribution of calcium atoms in an atomic beam generated using a dual-stage laser back-ablation apparatus. Distributions are measured using a velocity selective Doppler time-of-flight technique. They are Boltzmann-like with rms velocities corresponding to temperatures above the melting point for calcium. Contrary to a recent report in the literature, this method does not generate a subthermal atomic beam.
  • Microbeam radiation therapy (MRT) is a new oncology method currently under development for the treatment of inoperable pediatric brain tumors. Monte Carlo simulation, or the computational study of radiation transport in matter, is often used in radiotherapy to theoretically estimate the dose required for treatment. However, its potential use in MRT dose planning systems is currently hindered by the significant discrepancies that have been observed between measured and theoretical dose and the PVDR (peak to valley dose ratio). The need to resolve these discrepancies is driven by the desirability of making MRT available to humans in the next few years.more » This article aims to resolve some of the discrepancies by examining the simplifications adopted in previous MRT Monte Carlo studies, such as the common practice of commencing microbeam transport on the surface of the target which neglects the influence of the distributed synchrotron source, multislit collimator, and the beam divergence between them. This article uses PENELOPE Monte Carlo simulation to investigate the influence of these beamline components upstream of the target on the lateral dose profiles and PVDRs of an array of 25 microbeams. It also compares the dose profiles and PVDRs of a microbeam array produced from a single simulation (full array) to those produced from the superposition of a single microbeam profile (sup array). The effect of modeling the distributed source and the beam divergence was an increase in the absorbed dose in the penumbral and valley regions of the microbeam profiles. Inclusion of the multislit collimator resulted in differences of up to 5 {mu}m in the FWHM of microbeam profiles across the array, which led to minor variations in the corresponding PVDR yields.« less
  • No abstract prepared.