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Title: Development of a compact electron-cyclotron-resonance ion source for high-energy carbon-ion therapy

Abstract

Ion sources for medical facilities should have characteristics of easy maintenance, low electric power consumption, good stability, and long operation time without problems (one year or longer). For this, a 10 GHz compact electron-cyclotron-resonance ion source with all-permanent magnets (Kei2 source) was developed. The maximum mirror magnetic fields on the beam axis are 0.59 T at the extraction side and 0.87 T at the gas-injection side, while the minimum B strength is 0.25 T. These parameters have been optimized for the production of C{sup 4+} based on the experience at the 10 GHz NIRS-ECR ion source and a previous prototype compact source (Kei source). The Kei2 source has a diameter of 320 mm and a length of 295 mm. The beam intensity of C{sup 4+} was obtained to be 530 {mu}A under an extraction voltage of 40 kV. The beam stability was better than 6% at C{sup 4+} of 280 {mu}A during 90 h with no adjustment of the operation parameters. The details of the design and beam tests of the source are described in this paper.

Authors:
; ; ; ; ; ; ; ; ;  [1];  [2];  [2];  [2];  [3]
  1. Graduate School of Mechanical Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585 (Japan) and National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan)
  2. (Japan)
  3. (KVI), University of Groningen, NL-9747 AA Groningen (Netherlands)
Publication Date:
OSTI Identifier:
20723243
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 76; Journal Issue: 11; Other Information: DOI: 10.1063/1.2132267; (c) 2005 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
43 PARTICLE ACCELERATORS; CARBON IONS; DESIGN; ECR ION SOURCES; ELECTRIC POTENTIAL; ELECTRIC POWER; GAS INJECTION; GHZ RANGE 01-100; ION BEAMS; MAGNETIC MIRRORS; MAINTENANCE; OPERATION; PERMANENT MAGNETS; RADIOTHERAPY; STABILITY

Citation Formats

Muramatsu, M., Kitagawa, A., Sakamoto, Y., Sato, S., Sato, Y., Ogawa, Hirotsugu, Yamada, S., Ogawa, Hiroyuki, Yoshida, Y., Drentje, A.G., National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Accelerator Engineering Corporation, Ltd., 2-13-1 Konakadai, Inage, Chiba 263-0043, Department of Mechanical Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585, and Kernfysisch Versneller Instituut. Development of a compact electron-cyclotron-resonance ion source for high-energy carbon-ion therapy. United States: N. p., 2005. Web. doi:10.1063/1.2132267.
Muramatsu, M., Kitagawa, A., Sakamoto, Y., Sato, S., Sato, Y., Ogawa, Hirotsugu, Yamada, S., Ogawa, Hiroyuki, Yoshida, Y., Drentje, A.G., National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Accelerator Engineering Corporation, Ltd., 2-13-1 Konakadai, Inage, Chiba 263-0043, Department of Mechanical Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585, & Kernfysisch Versneller Instituut. Development of a compact electron-cyclotron-resonance ion source for high-energy carbon-ion therapy. United States. doi:10.1063/1.2132267.
Muramatsu, M., Kitagawa, A., Sakamoto, Y., Sato, S., Sato, Y., Ogawa, Hirotsugu, Yamada, S., Ogawa, Hiroyuki, Yoshida, Y., Drentje, A.G., National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555, Accelerator Engineering Corporation, Ltd., 2-13-1 Konakadai, Inage, Chiba 263-0043, Department of Mechanical Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585, and Kernfysisch Versneller Instituut. Tue . "Development of a compact electron-cyclotron-resonance ion source for high-energy carbon-ion therapy". United States. doi:10.1063/1.2132267.
@article{osti_20723243,
title = {Development of a compact electron-cyclotron-resonance ion source for high-energy carbon-ion therapy},
author = {Muramatsu, M. and Kitagawa, A. and Sakamoto, Y. and Sato, S. and Sato, Y. and Ogawa, Hirotsugu and Yamada, S. and Ogawa, Hiroyuki and Yoshida, Y. and Drentje, A.G. and National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 263-8555 and Accelerator Engineering Corporation, Ltd., 2-13-1 Konakadai, Inage, Chiba 263-0043 and Department of Mechanical Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585 and Kernfysisch Versneller Instituut},
abstractNote = {Ion sources for medical facilities should have characteristics of easy maintenance, low electric power consumption, good stability, and long operation time without problems (one year or longer). For this, a 10 GHz compact electron-cyclotron-resonance ion source with all-permanent magnets (Kei2 source) was developed. The maximum mirror magnetic fields on the beam axis are 0.59 T at the extraction side and 0.87 T at the gas-injection side, while the minimum B strength is 0.25 T. These parameters have been optimized for the production of C{sup 4+} based on the experience at the 10 GHz NIRS-ECR ion source and a previous prototype compact source (Kei source). The Kei2 source has a diameter of 320 mm and a length of 295 mm. The beam intensity of C{sup 4+} was obtained to be 530 {mu}A under an extraction voltage of 40 kV. The beam stability was better than 6% at C{sup 4+} of 280 {mu}A during 90 h with no adjustment of the operation parameters. The details of the design and beam tests of the source are described in this paper.},
doi = {10.1063/1.2132267},
journal = {Review of Scientific Instruments},
number = 11,
volume = 76,
place = {United States},
year = {Tue Nov 15 00:00:00 EST 2005},
month = {Tue Nov 15 00:00:00 EST 2005}
}
  • Heavy-ion cancer treatment is being carried out at the Heavy Ion Medical Accelerator in Chiba (HIMAC) with 140 to 400 MeV/n carbon ions at National Institute of Radiological Sciences (NIRS) since 1994. At NIRS, more than 4,000 patients have been treated, and the clinical efficiency of carbon ion radiotherapy has been demonstrated for many diseases. A more compact accelerator facility for cancer therapy is now being constricted at the Gunma University. In order to reduce the size of the injector (consists of ion source, low-energy beam transport and post-accelerator Linac include these power supply and cooling system), an ion sourcemore » requires production of highly charged carbon ions, lower electric power for easy installation of the source on a high-voltage platform, long lifetime and easy operation. A compact Electron Cyclotron Resonance Ion Source (ECRIS) with all permanent magnets is one of the best types for this purpose. An ECRIS has advantage for production of highly charged ions. A permanent magnet is suitable for reduce the electric power and cooling system. For this, a 10 GHz compact ECRIS with all permanent magnets (Kei2-source) was developed. The maximum mirror magnetic fields on the beam axis are 0.59 T at the extraction side and 0.87 T at the gas-injection side, while the minimum B strength is 0.25 T. These parameters have been optimized for the production of C{sup 4+} based on experience at the 10 GHz NIRS-ECR ion source. The Kei2-source has a diameter of 320 mm and a length of 295 mm. The beam intensity of C{sup 4+} was obtained to be 618 e{mu}A under an extraction voltage of 30 kV. Outline of the heavy ion therapy and development of the compact ion source for new facility are described in this paper.« less
  • A high-energy carbon-ion radiotherapy facility is under construction at Gunma University Heavy Ion Medical Centre (GHMC). Its design was based on a study of the heavy ion radiotherapy at the National Institute of Radiological Sciences (NIRS) in order to reduce the size and construction cost of the facility. A compact electron cyclotron resonance ion source (ECRIS) for Gunma University, called KeiGM, was installed in 2008. It is almost a copy of the prototype ECRIS Kei2 which was developed by NIRS; meanwhile this prototype produced over 1 e mA of C{sup 4+} using C{sub 2}H{sub 2} gas (660 W and 40more » kV). The beam intensity of C{sup 4+} was 600 e {mu}A with CH{sub 4} gas (250 W and 30 kV). The beam intensity satisfies the required value of 300 e {mu}A.« less
  • No abstract prepared.
  • LECR4 (Lanzhou electron cyclotron resonance ion source No. 4) has been successfully constructed at IMP and has also been connected with the Low Energy Beam Transport (LEBT) and Radio Frequency Quadrupole (RFQ) systems. These source magnet coils are cooled through evaporative cooling technology, which is the first attempt with an ECR ion source in the world. The maximum mirror field is 2.5 T (with iron plug) and the effective plasma chamber volume is 1.2 l. It was designed to be operated at 18 GHz and aimed to produce intense multiple charge state heavy ion beams for the linear injector projectmore » SSC-Linac at IMP. In February 2014, the first analyzed beam at 18 GHz was extracted. During about three months’ commissioning, some outstanding results have been achieved, such as 1.97 emA of O{sup 6+}, 1.7 emA of Ar{sup 8+}, 1.07 emA of Ar{sup 9+}, and 118 euA of Bi{sup 28+}. The source has also successfully delivered O{sup 5+} and Ar{sup 8+} ion beams for RFQ commissioning in April 2014. This paper will give a brief overview of the design of LECR4. Then, the latest results of this source at 18 GHz will be presented.« less
  • The Kei-source is a compact electron cyclotron resonance ion source using only permanent magnets and a frequency of 10 GHz. It was developed at the National Institute of Radiological Sciences (NIRS) for producing C{sup 4+} ions oriented for high-energy carbon therapy. It has also been used as an ion source for the NIRS-930 cyclotron. Its microwave band region for the traveling-wave-tube amplifier and maximum output power are 8–10 GHz and 350 W, respectively. Since 2006, it has provided various ion beams such as proton, deuteron, carbon, oxygen, and neon with sufficient intensity (200 μA for proton and deuteron, 50 μAmore » for C{sup 4+}, for example) and good stability for radioisotope production, tests of radiation damage, and basic research experiments. Its horizontal and vertical emittances were measured using a screen monitor and waist-scan. The present paper reports the current status of the Kei-source.« less