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Title: Comparison between Theoretical Calculation and Experimental Results of Excitation Functions for Production of Relevant Biomedical Radionuclides

Abstract

The radionuclide production for biomedical applications has been brought up in the years, as a special nuclear application, at INFN LASA Laboratory, particularly in co-operation with the JRC-Ispra of EC. Mainly scientific aspects concerning radiation detection and the relevant instruments, the measurements of excitation functions of the involved nuclear reactions, the requested radiochemistry studies and further applications have been investigated. On the side of the nuclear data evaluations, based on nuclear model calculations and critically selected experimental data, the appropriate competence has been developed at ENEA Division for Advanced Physics Technologies. A series of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET radiodiagnostics, are investigated. In this work, last revised measurements and model calculations are reviewed for excitation functions of natZn(d,X)64Cu, 66Ga reactions, referring to irradiation experiments at K=38 variable energy Cyclotron of JRC-Ispra. Concerning the reaction data for producing 186gRe and 211At/211gPo (including significant emission spectra) and 210At, most recent and critically selected experimental results are considered and discussed in comparison with model calculations paying special care to pre-equilibrium effects estimate and to the appropriate overall parameterization. Model calculations are presented for 226Ra(p,2n)225Ac reaction, according to the working program ofmore » the ongoing IAEA CRP on the matter.« less

Authors:
 [1]; ; ; ; ;  [2]
  1. ENEA, Division for Advanced Physics Technologies, via Don Fiammelli 2, I-40128 Bologna (Italy)
  2. Universita degli Studi di Milano, via F.lli Cervi 201, I-20090 Segrate, Milan (Italy)
Publication Date:
OSTI Identifier:
20722505
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 769; Journal Issue: 1; Conference: International conference on nuclear data for science and technology, Santa Fe, NM (United States), 26 Sep - 1 Oct 2004; Other Information: DOI: 10.1063/1.1945321; (c) 2005 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
73 NUCLEAR PHYSICS AND RADIATION PHYSICS; ACTINIUM 225; ASTATINE 210; ASTATINE 211; COMPARATIVE EVALUATIONS; COPPER 64; DEUTERON REACTIONS; EMISSION SPECTRA; EXCITATION FUNCTIONS; GALLIUM 66; NUCLEAR MODELS; POTASSIUM 38; PROTON REACTIONS; PROTON-NUCLEON INTERACTIONS; RADIATION DETECTION; RADIOCHEMISTRY; RADIOTHERAPY; RADIUM 226; VARIABLE ENERGY CYCLOTRONS

Citation Formats

Menapace, E, Birattari, C, Bonardi, M L, Groppi, F, Morzenti, S, Zona, C, and INFN-Milano, LASA, Radiochemistry Laboratory, via F.lli Cervi 201, I-20090 Segrate, Milan. Comparison between Theoretical Calculation and Experimental Results of Excitation Functions for Production of Relevant Biomedical Radionuclides. United States: N. p., 2005. Web. doi:10.1063/1.1945321.
Menapace, E, Birattari, C, Bonardi, M L, Groppi, F, Morzenti, S, Zona, C, & INFN-Milano, LASA, Radiochemistry Laboratory, via F.lli Cervi 201, I-20090 Segrate, Milan. Comparison between Theoretical Calculation and Experimental Results of Excitation Functions for Production of Relevant Biomedical Radionuclides. United States. https://doi.org/10.1063/1.1945321
Menapace, E, Birattari, C, Bonardi, M L, Groppi, F, Morzenti, S, Zona, C, and INFN-Milano, LASA, Radiochemistry Laboratory, via F.lli Cervi 201, I-20090 Segrate, Milan. 2005. "Comparison between Theoretical Calculation and Experimental Results of Excitation Functions for Production of Relevant Biomedical Radionuclides". United States. https://doi.org/10.1063/1.1945321.
@article{osti_20722505,
title = {Comparison between Theoretical Calculation and Experimental Results of Excitation Functions for Production of Relevant Biomedical Radionuclides},
author = {Menapace, E and Birattari, C and Bonardi, M L and Groppi, F and Morzenti, S and Zona, C and INFN-Milano, LASA, Radiochemistry Laboratory, via F.lli Cervi 201, I-20090 Segrate, Milan},
abstractNote = {The radionuclide production for biomedical applications has been brought up in the years, as a special nuclear application, at INFN LASA Laboratory, particularly in co-operation with the JRC-Ispra of EC. Mainly scientific aspects concerning radiation detection and the relevant instruments, the measurements of excitation functions of the involved nuclear reactions, the requested radiochemistry studies and further applications have been investigated. On the side of the nuclear data evaluations, based on nuclear model calculations and critically selected experimental data, the appropriate competence has been developed at ENEA Division for Advanced Physics Technologies. A series of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET radiodiagnostics, are investigated. In this work, last revised measurements and model calculations are reviewed for excitation functions of natZn(d,X)64Cu, 66Ga reactions, referring to irradiation experiments at K=38 variable energy Cyclotron of JRC-Ispra. Concerning the reaction data for producing 186gRe and 211At/211gPo (including significant emission spectra) and 210At, most recent and critically selected experimental results are considered and discussed in comparison with model calculations paying special care to pre-equilibrium effects estimate and to the appropriate overall parameterization. Model calculations are presented for 226Ra(p,2n)225Ac reaction, according to the working program of the ongoing IAEA CRP on the matter.},
doi = {10.1063/1.1945321},
url = {https://www.osti.gov/biblio/20722505}, journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 769,
place = {United States},
year = {Tue May 24 00:00:00 EDT 2005},
month = {Tue May 24 00:00:00 EDT 2005}
}