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Title: The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating

Abstract

Purpose: The correlation of the respiratory motion of external patient markers and abdominal tumors was examined. Data of this type are important for image-guided therapy techniques, such as respiratory gating, that monitor the movement of external fiducials. Methods and Materials: Fluoroscopy sessions for 4 patients with internal, radiopaque tumor fiducial clips were analyzed by computer vision techniques. The motion of the internal clips and the external markers placed on the patient's abdominal skin surface were quantified and correlated. Results: In general, the motion of the tumor and external markers were well correlated. The maximum amount of peak-to-peak craniocaudal tumor motion was 2.5 cm. The ratio of tumor motion to external-marker motion ranged from 0.85 to 7.1. The variation in tumor position for a given external-marker position ranged from 2 to 9 mm. The period of the breathing cycle ranged from 2.7 to 4.5 seconds, and the frequency patterns for both the tumor and the external markers were similar. Conclusions: Although tumor motion generally correlated well with external fiducial marker motion, relatively large underlying tumor motion can occur compared with external-marker motion and variations in the tumor position for a given marker position. Treatment margins should be determined on the basismore » of a detailed understanding of tumor motion, as opposed to relying only on external-marker information.« less

Authors:
 [1];  [2];  [1];  [2];  [1];  [1]
  1. Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States)
  2. Department of Computer Science, Boston University, Boston, MA (United States)
Publication Date:
OSTI Identifier:
20696191
Resource Type:
Journal Article
Journal Name:
International Journal of Radiation Oncology, Biology and Physics
Additional Journal Information:
Journal Volume: 61; Journal Issue: 5; Other Information: DOI: 10.1016/j.ijrobp.2004.12.013; PII: S0360-3016(04)03039-1; Copyright (c) 2005 Elsevier Science B.V., Amsterdam, Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0360-3016
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABDOMEN; FLUOROSCOPY; IMAGES; NEOPLASMS; PATIENTS; RESPIRATION; SKIN; THERAPY

Citation Formats

Gierga, David P, Brewer, Johanna, Sharp, Gregory C, Betke, Margrit, Willett, Christopher G, and Chen, George T.Y. The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating. United States: N. p., 2005. Web. doi:10.1016/j.ijrobp.2004.12.013.
Gierga, David P, Brewer, Johanna, Sharp, Gregory C, Betke, Margrit, Willett, Christopher G, & Chen, George T.Y. The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating. United States. https://doi.org/10.1016/j.ijrobp.2004.12.013
Gierga, David P, Brewer, Johanna, Sharp, Gregory C, Betke, Margrit, Willett, Christopher G, and Chen, George T.Y. 2005. "The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating". United States. https://doi.org/10.1016/j.ijrobp.2004.12.013.
@article{osti_20696191,
title = {The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating},
author = {Gierga, David P and Brewer, Johanna and Sharp, Gregory C and Betke, Margrit and Willett, Christopher G and Chen, George T.Y.},
abstractNote = {Purpose: The correlation of the respiratory motion of external patient markers and abdominal tumors was examined. Data of this type are important for image-guided therapy techniques, such as respiratory gating, that monitor the movement of external fiducials. Methods and Materials: Fluoroscopy sessions for 4 patients with internal, radiopaque tumor fiducial clips were analyzed by computer vision techniques. The motion of the internal clips and the external markers placed on the patient's abdominal skin surface were quantified and correlated. Results: In general, the motion of the tumor and external markers were well correlated. The maximum amount of peak-to-peak craniocaudal tumor motion was 2.5 cm. The ratio of tumor motion to external-marker motion ranged from 0.85 to 7.1. The variation in tumor position for a given external-marker position ranged from 2 to 9 mm. The period of the breathing cycle ranged from 2.7 to 4.5 seconds, and the frequency patterns for both the tumor and the external markers were similar. Conclusions: Although tumor motion generally correlated well with external fiducial marker motion, relatively large underlying tumor motion can occur compared with external-marker motion and variations in the tumor position for a given marker position. Treatment margins should be determined on the basis of a detailed understanding of tumor motion, as opposed to relying only on external-marker information.},
doi = {10.1016/j.ijrobp.2004.12.013},
url = {https://www.osti.gov/biblio/20696191}, journal = {International Journal of Radiation Oncology, Biology and Physics},
issn = {0360-3016},
number = 5,
volume = 61,
place = {United States},
year = {Fri Apr 01 00:00:00 EST 2005},
month = {Fri Apr 01 00:00:00 EST 2005}
}