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Title: Pixel Detectors For Diffraction Experiments At The Swiss Light Source

Abstract

The PILATUS detector (Pixel Apparatus for the SLS) is a large, quantum-limited area X-ray detector for protein crystallography which is currently under construction. Its basic units are modules with 16 CMOS chips bump-bonded to a large, continuously sensitive silicon sensor with 157x366 pixels of 217x217 {mu}m2, leading to an active area of 34x80 mm2. With a counting circuit in each pixel, X-rays are detected in single photon counting mode, leading to excellent, noise-free data. The main properties of the detector are an energy range of 6 to 30 keV, no back-ground due to leakage current or readout-noise, fast read-out time of 6.7 ms, a rate/pixel >104/s and a PSF of one pixel. PILATUS detectors are installed at the SLS X06SA protein crystallography beamline, and at both the surface diffraction (SD) station and the radiography and tomography (XTM) station of beamline X04SA. The detectors are operated at room temperature and thus are very easy to use. Experiments benefit from the ability to detect very weak diffraction spots with high precision. At the SD station and at the XTM station, which is equipped with a Bragg magnifier, diffraction, radiography and tomography experiments showed promising results. At beamline X06SA, a three-module array (1120x157more » pixels) with a readout time of 6.7 ms was tested. This system was used to collect fine phi-sliced protein crystal data in continuous sample rotation mode in which the crystal was continuously rotated with a slow angular velocity of 0.04 deg./s without any shutter operation. Exposure time per frame ranged from 100 ms to a few seconds, depending on the crystal. These initial experiments show the potential of this method.« less

Authors:
; ; ; ; ; ; ; ;  [1];  [2];  [3];  [4]
  1. Swiss Light Source (SLS), Paul Scherrer Institute, CH-5232 Villigen (Switzerland)
  2. Paul Scherrer Institute, CH-5232 Villigen (Switzerland)
  3. Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Mikazuki-cho, Sayo-gun, Hyogo 679-5198 (Japan)
  4. FRM II, Technische Universitaet Muenchen, D-85747, Garching (Germany)
Publication Date:
OSTI Identifier:
20652790
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 705; Journal Issue: 1; Conference: 8. international conference on synchrotron radiation instrumentation, San Francisco, CA (United States), 25-29 Aug 2003; Other Information: DOI: 10.1063/1.1757968; (c) 2004 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ANGULAR VELOCITY; COUNTING CIRCUITS; CRYSTALLOGRAPHY; KEV RANGE 01-10; KEV RANGE 10-100; LEAKAGE CURRENT; PROTEINS; READOUT SYSTEMS; SILICON; SWISS LIGHT SOURCE; SYNCHROTRON RADIATION; TEMPERATURE RANGE 0273-0400 K; TOMOGRAPHY; X-RAY DETECTION; X-RAY DIFFRACTION

Citation Formats

Huelsen, G, Eikenberry, E F, Schmitt, B, Schulze-Briese, C, Tomizaki, T, Stampanoni, M, Willmott, P, Patterson, B, Broennimann, Ch, Horisberger, R, Toyokawa, H, and Borchert, G L. Pixel Detectors For Diffraction Experiments At The Swiss Light Source. United States: N. p., 2004. Web. doi:10.1063/1.1757968.
Huelsen, G, Eikenberry, E F, Schmitt, B, Schulze-Briese, C, Tomizaki, T, Stampanoni, M, Willmott, P, Patterson, B, Broennimann, Ch, Horisberger, R, Toyokawa, H, & Borchert, G L. Pixel Detectors For Diffraction Experiments At The Swiss Light Source. United States. doi:10.1063/1.1757968.
Huelsen, G, Eikenberry, E F, Schmitt, B, Schulze-Briese, C, Tomizaki, T, Stampanoni, M, Willmott, P, Patterson, B, Broennimann, Ch, Horisberger, R, Toyokawa, H, and Borchert, G L. Wed . "Pixel Detectors For Diffraction Experiments At The Swiss Light Source". United States. doi:10.1063/1.1757968.
@article{osti_20652790,
title = {Pixel Detectors For Diffraction Experiments At The Swiss Light Source},
author = {Huelsen, G and Eikenberry, E F and Schmitt, B and Schulze-Briese, C and Tomizaki, T and Stampanoni, M and Willmott, P and Patterson, B and Broennimann, Ch and Horisberger, R and Toyokawa, H and Borchert, G L},
abstractNote = {The PILATUS detector (Pixel Apparatus for the SLS) is a large, quantum-limited area X-ray detector for protein crystallography which is currently under construction. Its basic units are modules with 16 CMOS chips bump-bonded to a large, continuously sensitive silicon sensor with 157x366 pixels of 217x217 {mu}m2, leading to an active area of 34x80 mm2. With a counting circuit in each pixel, X-rays are detected in single photon counting mode, leading to excellent, noise-free data. The main properties of the detector are an energy range of 6 to 30 keV, no back-ground due to leakage current or readout-noise, fast read-out time of 6.7 ms, a rate/pixel >104/s and a PSF of one pixel. PILATUS detectors are installed at the SLS X06SA protein crystallography beamline, and at both the surface diffraction (SD) station and the radiography and tomography (XTM) station of beamline X04SA. The detectors are operated at room temperature and thus are very easy to use. Experiments benefit from the ability to detect very weak diffraction spots with high precision. At the SD station and at the XTM station, which is equipped with a Bragg magnifier, diffraction, radiography and tomography experiments showed promising results. At beamline X06SA, a three-module array (1120x157 pixels) with a readout time of 6.7 ms was tested. This system was used to collect fine phi-sliced protein crystal data in continuous sample rotation mode in which the crystal was continuously rotated with a slow angular velocity of 0.04 deg./s without any shutter operation. Exposure time per frame ranged from 100 ms to a few seconds, depending on the crystal. These initial experiments show the potential of this method.},
doi = {10.1063/1.1757968},
journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 705,
place = {United States},
year = {2004},
month = {5}
}