Improved neutron sources for neutron capture enhanced fast neutron therapy
Fast neutron radiotherapy (FNT) can be combined with boron neutron capture therapy (BNCT). The selective incremental absorbed dose in the target volume that is thus obtained may be sufficient to produce a significant improvement in tumor control probability in some cases. Potential applications include certain non-small-cell lung tumors; head and neck tumors; prostate tumors; and possibly also glioblastoma multiform, an extremely refractory type of primary brain tumor. A class of modified neutron production targets has been developed to provide improved performance of the cyclotron-based clinical FNT facility at the University of Washington (UW) Medical Center for applications involving BNCT-enhanced FNT. The new targets produce neutron beams that feature essentially the same fast neutron physical depth-dose performance as the current UW system but with an increased fraction of BNCT enhancement.
- Research Organization:
- INEEL, Idaho Falls, ID (US)
- OSTI ID:
- 20093661
- Journal Information:
- Transactions of the American Nuclear Society, Vol. 82; Conference: 2000 Annual Meeting - American Nuclear Society, San Diego, CA (US), 06/04/2000--06/08/2000; Other Information: PBD: 2000; ISSN 0003-018X
- Country of Publication:
- United States
- Language:
- English
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