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Title: Frequencies of micronuclei in bank voles from zones of high radiation at Chernobyl, Ukraine

Abstract

A population of Clethrionomys glareolus (bank vole) from a highly radioactive area within the Chernobyl, Ukraine exclusion zone was sampled in June 1997 and in June and October 1998. Internal radiation doses from radiocesium were estimated to be as high as 8 rads/d. Total dose, which takes into account the internal dose form radiostrontium and the surrounding environment, was estimated to be 15 to 20 rads/d. In contrast, individuals from a reference population lying outside of the exclusion zone registered negligible levels of contamination. The authors used the micronucleus test in a double-blind study to analyze blood samples from 58 individuals. They scored more than 600,000 polychromatic erythrocytes (PCEs) but could not reject the null hypothesis that the frequency of micronucleated PCEs in voles exposed to radiation was equal to the frequency in unexposed voles. Results of their study stand in sharp contrast to earlier reports of increased frequencies of micronuclei in rodents exposed to fallout of the Chernobyl accident, but with radiation doses that were orders of magnitude lower than those reported here. Radio resistance and experimental methods are possible explanations for these differences in the results.

Authors:
;
Publication Date:
Research Org.:
Texas Tech Univ., Lubbock, TX (US)
Sponsoring Org.:
USDOE
OSTI Identifier:
20062549
DOE Contract Number:
FC09-96SR18546
Resource Type:
Journal Article
Resource Relation:
Journal Name: Environmental Toxicology and Chemistry; Journal Volume: 19; Journal Issue: 6; Other Information: PBD: Jun 2000
Country of Publication:
United States
Language:
English
Subject:
22 GENERAL STUDIES OF NUCLEAR REACTORS; 21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS; CHERNOBYLSK-4 REACTOR; UKRAINE; FALLOUT; VOLES; MUTATION FREQUENCY; CESIUM ISOTOPES; STRONTIUM ISOTOPES; RADIATION DOSES; BIOLOGICAL MODELS; CELL NUCLEI; REACTOR ACCIDENTS

Citation Formats

Rodgers, B.E., and Baker, R.J. Frequencies of micronuclei in bank voles from zones of high radiation at Chernobyl, Ukraine. United States: N. p., 2000. Web. doi:10.1897/1551-5028(2000)019<1644:FOMIBV>2.3.CO;2.
Rodgers, B.E., & Baker, R.J. Frequencies of micronuclei in bank voles from zones of high radiation at Chernobyl, Ukraine. United States. doi:10.1897/1551-5028(2000)019<1644:FOMIBV>2.3.CO;2.
Rodgers, B.E., and Baker, R.J. 2000. "Frequencies of micronuclei in bank voles from zones of high radiation at Chernobyl, Ukraine". United States. doi:10.1897/1551-5028(2000)019<1644:FOMIBV>2.3.CO;2.
@article{osti_20062549,
title = {Frequencies of micronuclei in bank voles from zones of high radiation at Chernobyl, Ukraine},
author = {Rodgers, B.E. and Baker, R.J.},
abstractNote = {A population of Clethrionomys glareolus (bank vole) from a highly radioactive area within the Chernobyl, Ukraine exclusion zone was sampled in June 1997 and in June and October 1998. Internal radiation doses from radiocesium were estimated to be as high as 8 rads/d. Total dose, which takes into account the internal dose form radiostrontium and the surrounding environment, was estimated to be 15 to 20 rads/d. In contrast, individuals from a reference population lying outside of the exclusion zone registered negligible levels of contamination. The authors used the micronucleus test in a double-blind study to analyze blood samples from 58 individuals. They scored more than 600,000 polychromatic erythrocytes (PCEs) but could not reject the null hypothesis that the frequency of micronucleated PCEs in voles exposed to radiation was equal to the frequency in unexposed voles. Results of their study stand in sharp contrast to earlier reports of increased frequencies of micronuclei in rodents exposed to fallout of the Chernobyl accident, but with radiation doses that were orders of magnitude lower than those reported here. Radio resistance and experimental methods are possible explanations for these differences in the results.},
doi = {10.1897/1551-5028(2000)019<1644:FOMIBV>2.3.CO;2},
journal = {Environmental Toxicology and Chemistry},
number = 6,
volume = 19,
place = {United States},
year = 2000,
month = 6
}
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