Device to improve detection in electro-chromatography

Garguilo, M G; Paul, P H; Rakestraw, D J

Title: Device to improve detection in electro-chromatography

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Abstract

Apparatus and method are disclosed for improving the resolution of non-pressure driven capillary chromatographic systems, and particularly for capillary electrochromatography (CEC) systems. By reducing the cross-sectional area of a packed capillary column by means of a second open capillary contiguous with the outlet end of a packed capillary column, where the packed capillary column has a cross sectional area of between about 2 and 5 times that of the open capillary column, the phenomenon of band broadening in the transition region between the open capillary and the packed capillary column, where the individual components of the mixture are analyzed, can be eliminated, thereby providing for a significant improvement in resolution and more accurate detection and analysis.

Authors:: Garguilo, M G; Paul, P H; Rakestraw, D J

Publication Date:: Tue May 30 00:00:00 EDT 2000

Sponsoring Org.:: USDOE

OSTI Identifier:: 20050820

DOE Contract Number:: AC04-94AL85000

Resource Type:: Patent

Resource Relation:: Other Information: PBD: 30 May 2000

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; EXTRACTION COLUMNS; CHROMATOGRAPHY; CAPILLARY FLOW; RESOLUTION; PERFORMANCE

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                    Garguilo, M G, Paul, P H, and Rakestraw, D J. Device to improve detection in electro-chromatography.  United States: N. p., 2000. 
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                    Garguilo, M G, Paul, P H, & Rakestraw, D J. Device to improve detection in electro-chromatography.  United States.

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                    Garguilo, M G, Paul, P H, and Rakestraw, D J. 2000.  
        "Device to improve detection in electro-chromatography".  United States.

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@article{osti_20050820,

  title        = {Device to improve detection in electro-chromatography},

  author       = {Garguilo, M G and Paul, P H and Rakestraw, D J},

  abstractNote = {Apparatus and method are disclosed for improving the resolution of non-pressure driven capillary chromatographic systems, and particularly for capillary electrochromatography (CEC) systems. By reducing the cross-sectional area of a packed capillary column by means of a second open capillary contiguous with the outlet end of a packed capillary column, where the packed capillary column has a cross sectional area of between about 2 and 5 times that of the open capillary column, the phenomenon of band broadening in the transition region between the open capillary and the packed capillary column, where the individual components of the mixture are analyzed, can be eliminated, thereby providing for a significant improvement in resolution and more accurate detection and analysis.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/20050820},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue May 30 00:00:00 EDT 2000},

  month        = {Tue May 30 00:00:00 EDT 2000}

}

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