Multiphase Drug Distribution and Exchange in Oil-in-Water Nanoemulsion Revealed by High-Resolution 19 F qNMR

Wang, Deyun; Park, Jin H.; Zheng, Jiwen; Cai, Bing; Keire, David A.; Chen, Kang

doi:10.1021/acs.molpharmaceut.2c00025

Multiphase Drug Distribution and Exchange in Oil-in-Water Nanoemulsion Revealed by High-Resolution ¹⁹ F qNMR

Journal Article · 03 June 2022 · Molecular Pharmaceutics

DOI:https://doi.org/10.1021/acs.molpharmaceut.2c00025· OSTI ID:1981953

^[1]; Park, Jin H. ^[2]; ^[3]; Cai, Bing ^[4]; ^[5]; ^[6]

Northeast Medical Products Laboratory, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food and Drug Administration, Jamaica, New York 11433, United States
Division of Therapeutic Performance, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States
Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States
Division of Liquid Based Products I, Office of Lifecycle Drug Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States
Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, St. Louis, Missouri 63110, United States
Division of Complex Drug Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States

Not provided.

Research Organization:: Oak Ridge Inst. for Science and Education (ORISE), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

DOE Contract Number:: SC0014664

OSTI ID:: 1981953

Journal Information:: Molecular Pharmaceutics, Vol. 19, Issue 7; ISSN 1543-8384

Publisher:: American Chemical Society (ACS)

Country of Publication:: United States

Language:: English

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