Structural and mutational characterization of a malate racemase from the LarA superfamily

Gatreddi, Santhosh; Urdiain-Arraiza, Julian; Desguin, Benoît; Hausinger, Robert P.; Hu, Jian

doi:10.1007/s10534-022-00372-x

Structural and mutational characterization of a malate racemase from the LarA superfamily

Journal Article · 19 February 2022 · Biometals

DOI:https://doi.org/10.1007/s10534-022-00372-x· OSTI ID:1981489

Gatreddi, Santhosh; Urdiain-Arraiza, Julian; Desguin, Benoît; ; Hu, Jian

Not provided.

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-06CH11357

OSTI ID:: 1981489

Journal Information:: Biometals, Vol. 36, Issue 2; ISSN 0966-0844

Publisher:: Springer Netherlands

Country of Publication:: United States

Language:: English

References (16)

iMOSFLM : a new graphical interface for diffraction-image processing with MOSFLM Battye, T. Geoff G.; Kontogiannis, Luke; Johnson, Owen Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4 https://doi.org/10.1107/S0907444910048675	journal	March 2011
Lactate racemase is a nickel-dependent enzyme activated by a widespread maturation system Desguin, Benoît; Goffin, Philippe; Viaene, Eric Nature Communications, Vol. 5, Issue 1 https://doi.org/10.1038/ncomms4615	journal	April 2014
A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase Desguin, Benoît; Zhang, Tuo; Soumillion, Patrice Science, Vol. 349, Issue 6243 https://doi.org/10.1126/science.aab2272	journal	July 2015
Nickel-pincer cofactor biosynthesis involves LarB-catalyzed pyridinium carboxylation and LarE-dependent sacrificial sulfur insertion Desguin, Benoît; Soumillion, Patrice; Hols, Pascal Proceedings of the National Academy of Sciences, Vol. 113, Issue 20 https://doi.org/10.1073/pnas.1600486113	journal	April 2016
Unexpected complexity in the lactate racemization system of lactic acid bacteria Desguin, Benoît; Soumillion, Patrice; Hausinger, Robert P. FEMS Microbiology Reviews, Vol. 41, Issue Supp_1 https://doi.org/10.1093/femsre/fux021	journal	June 2017
Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase Desguin, Benoît; Fellner, Matthias; Riant, Olivier Journal of Biological Chemistry, Vol. 293, Issue 32 https://doi.org/10.1074/jbc.RA118.003741	journal	June 2018
Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases Desguin, Benoît; Urdiain-Arraiza, Julian; Da Costa, Matthieu Scientific Reports, Vol. 10, Issue 1 https://doi.org/10.1038/s41598-020-74802-6	journal	October 2020
Features and development of Coot Emsley, P.; Lohkamp, B.; Scott, W. G. Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4 https://doi.org/10.1107/S0907444910007493	journal	March 2010
Scaling and assessment of data quality Evans, Philip Acta Crystallographica Section D Biological Crystallography, Vol. 62, Issue 1, p. 72-82 https://doi.org/10.1107/S0907444905036693	journal	December 2005
Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE Fellner, Matthias; Desguin, Benoît; Hausinger, Robert P. Proceedings of the National Academy of Sciences, Vol. 114, Issue 34 https://doi.org/10.1073/pnas.1704967114	journal	August 2017
Nickel–pincer nucleotide cofactor Hausinger, Robert P.; Desguin, Benoît; Fellner, Matthias Current Opinion in Chemical Biology, Vol. 47 https://doi.org/10.1016/j.cbpa.2018.06.019	journal	December 2018
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix Liebschner, Dorothee; Afonine, Pavel V.; Baker, Matthew L. Acta Crystallographica Section D Structural Biology, Vol. 75, Issue 10 https://doi.org/10.1107/S2059798319011471	journal	October 2019
The EMBL-EBI search and sequence analysis tools APIs in 2019 Madeira, Fábio; Park, Young mi; Lee, Joon Nucleic Acids Research, Vol. 47, Issue W1 https://doi.org/10.1093/nar/gkz268	journal	April 2019
Assimilation of D -Malate by Rhodobacter capsulatus E1F1 Martínez-Luque, Manuel; Castillo, Francisco; Blasco, Rafael Current Microbiology, Vol. 43, Issue 3 https://doi.org/10.1007/s002840010279	journal	June 2001
Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism Rankin, Joel A.; Mauban, Robert C.; Fellner, Matthias Biochemistry, Vol. 57, Issue 23 https://doi.org/10.1021/acs.biochem.8b00100	journal	February 2018
Deciphering key features in protein structures with the new ENDscript server Robert, Xavier; Gouet, Patrice Nucleic Acids Research, Vol. 42, Issue W1 https://doi.org/10.1093/nar/gku316	journal	April 2014

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