A Meta-Analysis of gRNA Library Screens Enables an Improved Understanding of the Impact of gRNA Folding and Structural Stability on CRISPR-Cas9 Activity

Moreb, Eirik A.; Lynch, Michael D.

doi:10.1089/crispr.2021.0084

A Meta-Analysis of gRNA Library Screens Enables an Improved Understanding of the Impact of gRNA Folding and Structural Stability on CRISPR-Cas9 Activity

Journal Article · 01 February 2022 · The CRISPR Journal

DOI:https://doi.org/10.1089/crispr.2021.0084· OSTI ID:1979480

Moreb, Eirik A. ^[1]; Lynch, Michael D. ^[1]

Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.

Not provided.

Research Organization:: Duke Univ., Durham, NC (United States)

Sponsoring Organization:: USDOE Office of Energy Efficiency and Renewable Energy (EERE)

DOE Contract Number:: EE0007563

OSTI ID:: 1979480

Journal Information:: The CRISPR Journal, Vol. 5, Issue 1; ISSN 2573-1599

Publisher:: Mary Ann Liebert, Inc.

Country of Publication:: United States

Language:: English

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