Production and diffusion of H 2 O 2 during the interaction of a direct current pulsed atmospheric pressure plasma jet on a hydrogel

Suresh, Manikandan; Kondeti, V. S. Santosh K.; Bruggeman, Peter J.

doi:10.1088/1361-6463/ac4ec6

Production and diffusion of H ₂ O ₂ during the interaction of a direct current pulsed atmospheric pressure plasma jet on a hydrogel

Journal Article · 04 February 2022 · Journal of Physics. D, Applied Physics

DOI:https://doi.org/10.1088/1361-6463/ac4ec6· OSTI ID:1979265

Suresh, Manikandan ^[1]; ;

OSTI

Abstract

The interaction of cold atmospheric pressure plasma jets with hydrogels has been used as a model system to study the interaction of plasmas with tissues. In this study, we analyze the diffusion of reactive oxygen species (in particular H₂O₂) and quantify the amount of plasma-produced H₂O₂species that penetrates into a gelatin hydrogel. We show that the diffusion constant of H₂O₂in 10% gelatin hydrogel is similar to its diffusion constant in water and that the production of H₂O₂in the hydrogel is significantly less than the production of H₂O₂in distilled water for the same plasma operation conditions suggesting that the scavenging of OH radicals at the plasma-gel interface significantly reduces the H₂O₂production.

Research Organization:: Univ. of Minnesota, Minneapolis, MN (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

DOE Contract Number:: SC0016053;

OSTI ID:: 1979265

Journal Information:: Journal of Physics. D, Applied Physics, Journal Name: Journal of Physics. D, Applied Physics Journal Issue: 18 Vol. 55; ISSN 0022-3727

Publisher:: IOP Publishing

Country of Publication:: United States

Language:: English

References (31)

Spatial-temporal distributions of ROS in model tissues treated by a He+O ₂ plasma jet Liu, Dingxin; He, Tongtong; Liu, Zhijie Plasma Processes and Polymers, Vol. 15, Issue 10 https://doi.org/10.1002/ppap.201800057	journal	July 2018
Hydrogen Peroxide Production in an Atmospheric Pressure RF Glow Discharge: Comparison of Models and Experiments Vasko, C. A.; Liu, D. X.; van Veldhuizen, E. M. Plasma Chemistry and Plasma Processing, Vol. 34, Issue 5 https://doi.org/10.1007/s11090-014-9559-8	journal	May 2014
Diffusion coefficients of oxygen, hydrogen peroxide and glucose in a hydrogel van Stroe-Biezen, S. A. M.; Everaerts, F. M.; Janssen, L. J. J. Analytica Chimica Acta, Vol. 273, Issue 1-2 https://doi.org/10.1016/0003-2670(93)80202-V	journal	February 1993
The role of ferrous ion in Fenton and photo-Fenton processes for the degradation of phenol Kavitha, V.; Palanivelu, K. Chemosphere, Vol. 55, Issue 9 https://doi.org/10.1016/j.chemosphere.2003.12.022	journal	June 2004
Long-lived and short-lived reactive species produced by a cold atmospheric pressure plasma jet for the inactivation of Pseudomonas aeruginosa and Staphylococcus aureus Kondeti, V. S. Santosh K.; Phan, Chi Q.; Wende, Kristian Free Radical Biology and Medicine, Vol. 124 https://doi.org/10.1016/j.freeradbiomed.2018.05.083	journal	August 2018
Transcutaneous plasma stress: From soft-matter models to living tissues Lu, X.; Keidar, M.; Laroussi, M. Materials Science and Engineering: R: Reports, Vol. 138 https://doi.org/10.1016/j.mser.2019.04.002	journal	October 2019
Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects Lu, X.; Naidis, G. V.; Laroussi, M. Physics Reports, Vol. 630 https://doi.org/10.1016/j.physrep.2016.03.003	journal	May 2016
Quantitative Measurements of HO ₂ and Other Products of n -Butane Oxidation (H ₂ O ₂ , H ₂ O, CH ₂ O, and C ₂ H ₄ ) at Elevated Temperatures by Direct Coupling of a Jet-Stirred Reactor with Sampling Nozzle and Cavity Ring-Down Spectroscopy (cw-CRDS) Djehiche, Mokhtar; Le Tan, Ngoc Linh; Jain, Chaithanya D. Journal of the American Chemical Society, Vol. 136, Issue 47 https://doi.org/10.1021/ja510719k	journal	November 2014
Perspectives on cold atmospheric plasma (CAP) applications in medicine von Woedtke, Thomas; Emmert, Steffen; Metelmann, Hans-Robert Physics of Plasmas, Vol. 27, Issue 7 https://doi.org/10.1063/5.0008093	journal	July 2020
A ‘tissue model’ to study the plasma delivery of reactive oxygen species Szili, Endre J.; Bradley, James W.; Short, Robert D. Journal of Physics D: Applied Physics, Vol. 47, Issue 15 https://doi.org/10.1088/0022-3727/47/15/152002	journal	March 2014
Atmospheric pressure plasma jets interacting with liquid covered tissue: touching and not-touching the liquid Norberg, Seth A.; Tian, Wei; Johnsen, Eric Journal of Physics D: Applied Physics, Vol. 47, Issue 47 https://doi.org/10.1088/0022-3727/47/47/475203	journal	November 2014
Probing the transport of plasma-generated RONS in an agarose target as surrogate for real tissue: dependency on time, distance and material composition Szili, Endre J.; Oh, Jun-Seok; Hong, Sung-Ha Journal of Physics D: Applied Physics, Vol. 48, Issue 20 https://doi.org/10.1088/0022-3727/48/20/202001	journal	April 2015
How to assess the plasma delivery of RONS into tissue fluid and tissue Oh, Jun-Seok; Szili, Endre J.; Gaur, Nishtha Journal of Physics D: Applied Physics, Vol. 49, Issue 30 https://doi.org/10.1088/0022-3727/49/30/304005	journal	July 2016
Atmospheric plasma generates oxygen atoms as oxidizing species in aqueous solutions Hefny, Mohamed Mokhtar; Pattyn, Cedric; Lukes, Petr Journal of Physics D: Applied Physics, Vol. 49, Issue 40 https://doi.org/10.1088/0022-3727/49/40/404002	journal	September 2016
Atmospheric-pressure plasma sources for biomedical applications Park, G. Y.; Park, S. J.; Choi, M. Y. Plasma Sources Science and Technology, Vol. 21, Issue 4 https://doi.org/10.1088/0963-0252/21/4/043001	journal	June 2012
Aqueous-phase chemistry and bactericidal effects from an air discharge plasma in contact with water: evidence for the formation of peroxynitrite through a pseudo-second-order post-discharge reaction of H ₂ O ₂ and HNO ₂ Lukes, P.; Dolezalova, E.; Sisrova, I. Plasma Sources Science and Technology, Vol. 23, Issue 1 https://doi.org/10.1088/0963-0252/23/1/015019	journal	February 2014
The 2017 Plasma Roadmap: Low temperature plasma science and technology Adamovich, I.; Baalrud, S. D.; Bogaerts, A. Journal of Physics D: Applied Physics, Vol. 50, Issue 32 https://doi.org/10.1088/1361-6463/aa76f5	journal	July 2017
Cold atmospheric plasma-induced acidification of tissue surface: visualization and quantification using agarose gel models Busco, Giovanni; Omran, Azadeh Valinataj; Ridou, Loïck Journal of Physics D: Applied Physics, Vol. 52, Issue 24 https://doi.org/10.1088/1361-6463/ab1119	journal	April 2019
Spatially and temporally resolved H and OH densities in a nanosecond pulsed plasma jet: an analysis of the radical generation, transport, recombination and memory effects Yue, Yuanfu; Jiang, Jingkai; Kondeti, V. S. Santosh K. Journal of Physics D: Applied Physics, Vol. 54, Issue 11 https://doi.org/10.1088/1361-6463/abce2a	journal	January 2021
Tuning plasma parameters to control reactive species fluxes to substrates in the context of plasma catalysis Jiang, Jingkai; Bruggeman, Peter J. Journal of Physics D: Applied Physics, Vol. 54, Issue 21 https://doi.org/10.1088/1361-6463/abe89a	journal	March 2021
Gel models to assess distribution and diffusion of reactive species from cold atmospheric plasma: an overview for plasma medicine applications Thulliez, Max; Bastin, Orianne; Nonclercq, Antoine Journal of Physics D: Applied Physics, Vol. 54, Issue 46 https://doi.org/10.1088/1361-6463/ac1623	journal	August 2021
Analysis of conductive target influence in plasma jet experiments through helium metastable and electric field measurements Darny, T.; Pouvesle, J-M; Puech, V. Plasma Sources Science and Technology, Vol. 26, Issue 4 https://doi.org/10.1088/1361-6595/aa5b15	journal	March 2017
Foundations of atmospheric pressure non-equilibrium plasmas Bruggeman, Peter J.; Iza, Felipe; Brandenburg, Ronny Plasma Sources Science and Technology, Vol. 26, Issue 12 https://doi.org/10.1088/1361-6595/aa97af	journal	November 2017
Effect of plasma on gas flow and air concentration in the effluent of a pulsed cold atmospheric pressure helium plasma jet Van Doremaele, E. R. W.; Kondeti, V. S. S. K.; Bruggeman, P. J. Plasma Sources Science and Technology, Vol. 27, Issue 9 https://doi.org/10.1088/1361-6595/aadbd3	journal	September 2018
HO ₂ reaction kinetics in an atmospheric pressure plasma jet determined by cavity ring-down spectroscopy Gianella, M.; Reuter, S.; Press, S. A. Plasma Sources Science and Technology, Vol. 27, Issue 9 https://doi.org/10.1088/1361-6595/aadf01	journal	September 2018
Physical and biological mechanisms of direct plasma interaction with living tissue Dobrynin, Danil; Fridman, Gregory; Friedman, Gary New Journal of Physics, Vol. 11, Issue 11 https://doi.org/10.1088/1367-2630/11/11/115020	journal	November 2009
Characterization of the effluent of a He/O ₂ microscale atmospheric pressure plasma jet by quantitative molecular beam mass spectrometry Ellerweg, D.; Benedikt, J.; von Keudell, A. New Journal of Physics, Vol. 12, Issue 1 https://doi.org/10.1088/1367-2630/12/1/013021	journal	January 2010
The kinetics of iodide oxidation by hydrogen peroxide in acid solution Milenković, M. C.; Stanisavljev, D. R. Russian Journal of Physical Chemistry A, Vol. 85, Issue 13 https://doi.org/10.1134/S0036024411130140	journal	December 2011
Two-dimensional concentration distribution of reactive oxygen species transported through a tissue phantom by atmospheric-pressure plasma-jet irradiation Kawasaki, Toshiyuki; Sato, Akihiro; Kusumegi, Shota Applied Physics Express, Vol. 9, Issue 7 https://doi.org/10.7567/APEX.9.076202	journal	June 2016
Control of reactive oxygen and nitrogen species production in liquid by nonthermal plasma jet with controlled surrounding gas Ito, Taiki; Uchida, Giichiro; Nakajima, Atsushi Japanese Journal of Applied Physics, Vol. 56, Issue 1S https://doi.org/10.7567/JJAP.56.01AC06	journal	December 2016
Transportation of reactive oxygen species in a tissue phantom after plasma irradiation Kawasaki, Toshiyuki; Kuroeda, Gouya; Sei, Ryuhei Japanese Journal of Applied Physics, Vol. 57, Issue 1S https://doi.org/10.7567/JJAP.57.01AG01	journal	November 2017

Similar Records

Production and diffusion of H₂O₂ during the interaction of a direct current pulsed atmospheric pressure plasma jet on a hydrogel

Journal Article · 2022 · Journal of Physics. D, Applied Physics · OSTI ID:3024930

Plasma dynamics, instabilities and OH generation in a pulsed atmospheric pressure plasma with liquid cathode: a diagnostic study

Journal Article · 2022 · Plasma Sources Science and Technology · OSTI ID:1979312

Spatially and temporally resolved H and OH densities in a nanosecond pulsed plasma jet: an analysis of the radical generation, transport, recombination and memory effects

Journal Article · 2021 · Journal of Physics. D, Applied Physics · OSTI ID:1852088

Related Subjects

Physics

Production and diffusion of H 2 O 2 during the interaction of a direct current pulsed atmospheric pressure plasma jet on a hydrogel

Citation Formats

References (31)

Similar Records

Related Subjects

Production and diffusion of H ₂ O ₂ during the interaction of a direct current pulsed atmospheric pressure plasma jet on a hydrogel