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Deep-Learning Electron Diffractive Imaging.

Journal Article · · Physical review letters

We report the development of deep-learning coherent electron diffractive imaging at subangstrom resolution using convolutional neural networks (CNNs) trained with only simulated data. We experimentally demonstrate this method by applying the trained CNNs to recover the phase images from electron diffraction patterns of twisted hexagonal boron nitride, monolayer graphene, and a gold nanoparticle with comparable quality to those reconstructed by a conventional ptychographic algorithm. Fourier ring correlation between the CNN and ptychographic images indicates the achievement of a resolution in the range of 0.70 and 0.55 Å. We further develop CNNs to recover the probe function from the experimental data. The ability to replace iterative algorithms with CNNs and perform real-time atomic imaging from coherent diffraction patterns is expected to find applications in the physical and biological sciences.

Research Organization:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22), Scientific User Facilities Division (SC-22.3 )
DOE Contract Number:
AC02-05CH11231
OSTI ID:
1924475
Journal Information:
Physical review letters, Vol. 130, Issue 1
Country of Publication:
United States
Language:
English

References (40)

Extending the methodology of X-ray crystallography to allow imaging of micrometre-sized non-crystalline specimens journal July 1999
Beyond crystallography: Diffractive imaging using coherent x-ray light sources journal April 2015
Hard-X-Ray Lensless Imaging of Extended Objects journal January 2007
High-Resolution Scanning X-ray Diffraction Microscopy journal July 2008
Beugung im inhomogenen Primärstrahlwellenfeld. I. Prinzip einer Phasenmessung von Elektronenbeungungsinterferenzen journal July 1969
Ptychographic X-ray computed tomography at the nanoscale journal September 2010
Ptychographic electron microscopy using high-angle dark-field scattering for sub-nanometre resolution imaging journal January 2012
Chemical composition mapping with nanometre resolution by soft X-ray microscopy journal September 2014
Simultaneous atomic-resolution electron ptychography and Z-contrast imaging of light and heavy elements in complex nanostructures journal August 2016
Subwavelength coherent imaging of periodic samples using a 13.5 nm tabletop high-harmonic light source journal March 2017
High-resolution non-destructive three-dimensional imaging of integrated circuits journal March 2017
Electron ptychographic microscopy for three-dimensional imaging journal July 2017
Electron Ptychographic Diffractive Imaging of Boron Atoms in LaB6 Crystals journal June 2017
Correlative 3D x-ray fluorescence and ptychographic tomography of frozen-hydrated green algae journal November 2018
Multi-slice ptychographic tomography journal February 2018
Electron ptychography of 2D materials to deep sub-ångström resolution journal July 2018
Potential of Attosecond Coherent Diffractive Imaging journal August 2020
Low-dose phase retrieval of biological specimens using cryo-electron ptychography journal June 2020
X-ray linear dichroic ptychography journal January 2021
Electron ptychography achieves atomic-resolution limits set by lattice vibrations journal May 2021
Deep learning in neural networks: An overview journal January 2015
Image Super-Resolution Using Deep Convolutional Networks journal February 2016
Deep learning microscopy journal January 2017
Lensless computational imaging through deep learning journal January 2017
AI-enabled high-resolution scanning coherent diffraction imaging journal July 2020
Complex imaging of phase domains by deep neural networks journal January 2021
Phase retrieval from the magnitude of the Fourier transforms of nonperiodic objects journal January 1998
On the interplay between physical and content priors in deep learning for computational imaging journal January 2020
An improved ptychographical phase retrieval algorithm for diffractive imaging journal September 2009
Tuning colour centres at a twisted hexagonal boron nitride interface journal July 2022
Advanced Computing in Electron Microscopy book January 2010
Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy journal October 2003
Contrast transfer and noise considerations in focused-probe electron ptychography journal February 2021
Real-Time Interactive 4D-STEM Phase-Contrast Imaging From Electron Event Representation Data: Less computation with the right representation journal January 2022
Efficient phase contrast imaging in STEM using a pixelated detector. Part 1: Experimental demonstration at atomic resolution journal April 2015
Electron tomography at 2.4-ångström resolution journal March 2012
Atomic electron tomography: 3D structures without crystals journal September 2016
Ptychographic atomic electron tomography: Towards three-dimensional imaging of individual light atoms in materials journal November 2020
Determining the three-dimensional atomic structure of an amorphous solid journal March 2021
Three-dimensional atomic packing in amorphous solids with liquid-like structure journal October 2021

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