Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
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October 2015 |
Host and Pathway Engineering for Enhanced Lycopene Biosynthesis in Yarrowia lipolytica
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November 2017 |
Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in Komagataella phaffii
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December 2019 |
CRISPR/Cas9 cleavage efficiency regression through boosting algorithms and Markov sequence profiling
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April 2018 |
Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin
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March 2021 |
Guide RNA Engineering Enables Dual Purpose CRISPR-Cpf1 for Simultaneous Gene Editing and Gene Regulation in Yarrowia lipolytica
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March 2020 |
Deep learning improves prediction of CRISPR–Cpf1 guide RNA activity
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January 2018 |
Development of the CRISPR/Cas9 System for Targeted Gene Disruption in Aspergillus fumigatus
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November 2015 |
DeepCRISPR: optimized CRISPR guide RNA design by deep learning
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June 2018 |
Improved sgRNA design in bacteria via genome-wide activity profiling
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June 2018 |
Genome dependent Cas9/gRNA search time underlies sequence dependent gRNA activity
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August 2021 |
Combining metabolic engineering and process optimization to improve production and secretion of fatty acids
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November 2016 |
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
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June 2012 |
Optimizing Oleaginous Yeast Cell Factories for Flavonoids and Hydroxylated Flavonoids Biosynthesis
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October 2019 |
Sequence Assembly of Yarrowia lipolytica Strain W29/CLIB89 Shows Transposable Element Diversity
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September 2016 |
Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica
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September 2019 |
Engineering xylose utilization in Yarrowia lipolytica by understanding its cryptic xylose pathway
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July 2016 |
CRISPR–Cas9-enabled genetic disruptions for understanding ethanol and ethyl acetate biosynthesis in Kluyveromyces marxianus
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June 2017 |
sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity
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February 2017 |
Highly parallel genome variant engineering with CRISPR–Cas9
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April 2018 |
The influence of eukaryotic chromatin state on CRISPR–Cas9 editing efficiencies
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February 2019 |
Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica
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November 2016 |
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
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December 2017 |
The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2020 update
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June 2020 |
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
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October 2014 |
Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR/Cas9 system
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May 2015 |
CRISPR-Mediated Genome Editing and Gene Repression in Scheffersomyces stipitis
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July 2018 |
Nucleosomes impede Cas9 access to DNA in vivo and in vitro
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March 2016 |
Multiplex Genome Engineering Using CRISPR/Cas Systems
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January 2013 |
Highly Multiplexed CRISPRi Repression of Respiratory Functions Enhances Mitochondrial Localized Ethyl Acetate Biosynthesis in Kluyveromyces marxianus
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October 2018 |
Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation
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September 2014 |
Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica
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July 2013 |
Sequence determinants of improved CRISPR sgRNA design
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June 2015 |
The Role of Nucleosome Positioning in the Evolution of Gene Regulation
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July 2010 |
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
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January 2016 |
Nucleosomes inhibit target cleavage by CRISPR-Cas9 in vivo
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September 2018 |
Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR–Cas9-Mediated Genome Editing in Yarrowia lipolytica
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January 2016 |
Development of a CRISPR/Cas9-Based Tool for Gene Deletion in Issatchenkia orientalis
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June 2019 |
DeeplyEssential: a deep neural network for predicting essential genes in microbes
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September 2020 |
Genome and metabolic engineering in non-conventional yeasts: Current advances and applications
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September 2017 |
CRISPRi repression of nonhomologous end-joining for enhanced genome engineering via homologous recombination in Yarrowia lipolytica
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September 2017 |
Identifying essential genes across eukaryotes by machine learning
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October 2021 |
Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production
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January 2014 |