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Peptide therapeutics: current status and future directions
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journal
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January 2015 |
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Tunable Degradation of Maleimide–Thiol Adducts in Reducing Environments
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October 2011 |
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Glucagon-like peptide 1 in health and disease
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May 2018 |
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Current ADC Linker Chemistry
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March 2015 |
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Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
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January 2013 |
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Diverse Protein Architectures and α-N-Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters
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March 2022 |
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Distinct Autocatalytic α- N- Methylating Precursors Expand the Borosin RiPP Family of Peptide Natural Products
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May 2019 |
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Mechanistic Basis for Ribosomal Peptide Backbone Modifications
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April 2019 |
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Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients
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November 2014 |
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Therapeutic peptides: Historical perspectives, current development trends, and future directions
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June 2018 |
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Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products
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June 2017 |
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AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP
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October 2006 |
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Targeting of extracellular protein–protein interactions with macrocyclic peptides
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June 2021 |
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Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
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April 2012 |
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Advances in oral peptide therapeutics
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December 2019 |
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Structural Diversity and Biological Activities of the Cyclodipeptides from Fungi
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November 2017 |
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RNA Display Methods for the Discovery of Bioactive Macrocycles
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November 2018 |
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Strategies for transitioning macrocyclic peptides to cell-permeable drug leads
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December 2017 |
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GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
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journal
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September 2012 |
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Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
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September 2021 |
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Engineering of a Peptide α‐N‐Methyltransferase to Methylate Non‐Proteinogenic Amino Acids
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journal
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May 2021 |
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Insect Peptides - Perspectives in Human Diseases Treatment
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October 2017 |
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Substrate Plasticity of a Fungal Peptide α-N-Methyltransferase
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June 2020 |
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Stapled Helical Peptides Bearing Different Anchoring Residues
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August 2020 |
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N‐Methylated Peptide Synthesis via Generation of an Acyl N‐Methylimidazolium Cation Accelerated by a Brønsted Acid
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May 2020 |
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Talaropeptides A-D: Structure and Biosynthesis of Extensively N-methylated Linear Peptides From an Australian Marine Tunicate-Derived Talaromyces sp.
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journal
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September 2018 |
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Peptide chemistry toolbox – Transforming natural peptides into peptide therapeutics
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June 2018 |
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Conotoxins: Chemistry and Biology
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journal
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October 2019 |
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YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function
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journal
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March 2017 |
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New developments in RiPP discovery, enzymology and engineering
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journal
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January 2021 |
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Peptidomimetic toolbox for drug discovery
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journal
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January 2020 |
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Non-Peptidic Small Molecule Components from Cone Snail Venoms
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journal
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May 2021 |
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Recent advances in the development of anti-infective peptoids
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journal
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January 2020 |
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Structure Determinants of Lagunamide A for Anticancer Activity and Its Molecular Mechanism of Mitochondrial Apoptosis
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journal
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October 2016 |
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Peptides and peptide conjugates: therapeutics on the upward path
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journal
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August 2012 |
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Design, synthesis, and diversification of ribosomally derived peptide macrocycles
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journal
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August 2013 |
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Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library
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journal
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December 2011 |
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FDA-approved small-molecule kinase inhibitors
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journal
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July 2015 |
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A Self-Sacrificing N -Methyltransferase Is the Precursor of the Fungal Natural Product Omphalotin
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journal
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July 2017 |
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Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40
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journal
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August 2013 |
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Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N-Methyltransferases in Bacteria
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journal
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January 2022 |
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A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds
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journal
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August 2018 |
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Chemical protein synthesis: Inventing synthetic methods to decipher how proteins work
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journal
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September 2017 |
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Cyclic peptide oral bioavailability: Lessons from the past: Cyclic Peptide Oral Bioavailability
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November 2016 |
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An Evaluation of Peptide-Bond Isosteres
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July 2011 |
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Commemorating insulin's centennial: engineering insulin pharmacology towards physiology
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August 2021 |
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Molecular Basis for Autocatalytic Backbone N -Methylation in RiPP Natural Product Biosynthesis
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journal
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September 2018 |
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N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
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journal
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October 2008 |
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Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides
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journal
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January 2010 |
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Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis
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journal
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September 2014 |
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Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water
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journal
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January 2015 |
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Insect Antimicrobial Peptides, a Mini Review
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journal
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November 2018 |
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Orally Active Peptides: Is There a Magic Bullet?
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October 2018 |
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From epoxomicin to carfilzomib: chemistry, biology, and medical outcomes
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January 2013 |