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Engineering a Conformationally Switchable Artificial Metalloprotein

Journal Article · · J. Am. Chem. Soc.
DOI:https://doi.org/10.1021/jacs.2c08885· OSTI ID:1902356
Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; NIH; OTHER U.S. STATES
DOE Contract Number:
NONE;
OSTI ID:
1902356
Journal Information:
J. Am. Chem. Soc., Journal Name: J. Am. Chem. Soc. Journal Issue: (47) Vol. 144
Country of Publication:
United States
Language:
ENGLISH

References (67)

Protein Conformational Switches: From Nature to Design journal June 2012
The Crystal Structure of Glutamine-binding Protein fromEscherichia coli journal September 1996
The structure of glutamine-binding protein complexed with glutamine at 1.94 Å resolution: comparisons with other amino acid binding proteins journal April 1998
Probing heart cytochromec oxidase structure and function by infrared spectroscopy journal April 1993
Proton nuclear magnetic resonance studies on glutaminebinding protein from Escherichia coli journal December 1989
Periplasmic binding proteins: a versatile superfamily for protein engineering journal August 2004
Engineering Metalloprotein Functions in Designed and Native Scaffolds journal December 2019
Fourier-transform infrared studies on azide-binding to the binuclear center of theEscherichia coli bo-type ubiquinol oxidase1 journal April 1999
A Binding Protein for Glutamine and Its Relation to Active Transport in Escherichia coli journal November 1971
Interaction of disulfides with methylcobaloxime journal January 1979
[20] Processing of X-ray diffraction data collected in oscillation mode book January 1997
Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities journal August 2016
Beyond the Second Coordination Sphere: Engineering Dirhodium Artificial Metalloenzymes To Enable Protein Control of Transition Metal Catalysis journal March 2019
Designing Artificial Metalloenzymes by Tuning of the Environment beyond the Primary Coordination Sphere journal July 2022
Artificial Metalloenzymes: Challenges and Opportunities journal July 2019
Bioinspired Hydrogen Bond Motifs in Ligand Design:  The Role of Noncovalent Interactions in Metal Ion Mediated Activation of Dioxygen journal January 2005
Artificial Metalloenzymes Based on the Biotin−Avidin Technology: Enantioselective Catalysis and Beyond journal January 2011
FTIR Analysis of the Interaction of Azide with Horse Heart Myoglobin Variants journal June 1994
Coupling of spin, substrate, and redox equilibriums in cytochrome P450 journal November 1976
Infrared studies of azide bound to myoglobin and hemoglobin temperature dependence of ionicity journal February 1972
Infrared studies of azido, cyano, and other derivatives of metmyoglobin, methemoglobin, and hemins journal June 1970
Pre-Steady-State and Steady-State Kinetic Analysis of E. coli Class I Ribonucleotide Reductase journal September 2003
Fundamental Challenges in Mechanistic Enzymology: Progress toward Understanding the Rate Enhancements of Enzymes journal March 2013
Ligand-Free Open−Closed Transitions of Periplasmic Binding Proteins: The Case of Glutamine-Binding Protein journal March 2010
Fourier Transform Infrared Analysis of the Interaction of Azide with the Active Site of Oxidized and Reduced Bovine Cu,Zn Superoxide Dismutase journal March 1998
Thermodynamic and Kinetic Studies on Carbon−Cobalt Bond Homolysis by Ribonucleoside Triphosphate Reductase:  The Importance of Entropy in Catalysis journal December 1998
Cis and trans effects on the proton magnetic resonance spectra of cobaloximes journal July 1974
The First X-ray Structural Evidence Demonstrating Thiolate Coordination in an Organocobalt B12 Model Complex:  Implications for Methionine Synthase journal January 1997
A mechanistic investigation of cobaloxime complexes containing good trans labilizing ligands, including spectroscopic and rate comparisons journal February 1978
An unusually long cobalt-carbon bond. Molecular structure of trans-bis(dimethylglyoximato)(isopropyl)(pyridine)cobalt(III). Implications with regard to the conformational trigger mechanism of cobalt-carbon bond cleavage in coenzyme B12 journal October 1979
Coenzyme B12 model studies. Equilibriums and kinetics of axial ligation of methylaquocobaloxime by thiols journal March 1972
Ligand-exchange kinetics in methylatobis(dimethylglyoximato)cobalt(III) complexes journal August 1969
Conformational Gating of Electron Transfer from the Nitrogenase Fe Protein to MoFe Protein journal May 2010
Function of the Diiron Cluster of Escherichia coli Class Ia Ribonucleotide Reductase in Proton-Coupled Electron Transfer journal May 2013
Entropic Origin of Cobalt–Carbon Bond Cleavage Catalysis in Adenosylcobalamin-Dependent Ethanolamine Ammonia-Lyase journal October 2013
Determination of the Solution-Bound Conformation of an Amino Acid Binding Protein by NMR Paramagnetic Relaxation Enhancement: Use of a Single Flexible Paramagnetic Probe with Improved Estimation of Its Sampling Space journal June 2009
An Interprotein Co–S Coordination Complex in the B12-Trafficking Pathway journal September 2020
Optimization of Enzyme Mechanism along the Evolutionary Trajectory of a Computationally Designed (Retro-)Aldolase journal August 2017
Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins journal November 2017
Artificial Metalloproteins: At the Interface between Biology and Chemistry journal June 2022
Evidence for steric trans influences and effects in (perfluoroisopropyl)cobaloximes. Molecular structure of trans-bis-(dimethylglyoximato)(triphenylphosphine)(perfluoroisopropyl)cobalt(III) journal March 1991
Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR journal October 2007
Design of functional metalloproteins journal August 2009
Enzymatic assembly of DNA molecules up to several hundred kilobases journal April 2009
Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM journal August 2018
A single residue controls electron transfer gating in photosynthetic reaction centers journal March 2017
Structural chemistry of alkylcobaloximes. Structural evidence for a hydroxocobaloxime and molecular structure of trans-bis(dimethylglyoximato)methylpyridinecobalt(III) and trans-bis(dimethylglyoximato)methyl(3-N-methylimidazole)cobalt(III) journal January 1976
Protein‒coenzyme interactions in adenosylcobalamin-dependent glutamate mutase journal April 2001
Geometric and electronic structure differences between the type 3 copper sites of the multicopper oxidases and hemocyanin/tyrosinase journal April 2009
The entropic contributions in vitamin B 12 enzymes still reflect the electrostatic paradigm journal March 2015
Design of a single protein that spans the entire 2-V range of physiological redox potentials journal December 2015
Electrostatic Origin of the Catalytic Power of Enzymes and the Role of Preorganized Active Sites journal October 1998
The Crystal and Molecular Structure Trans-Azidobis (Dimethylglyoximato) Pyridinecobalt(Iii) journal April 1978
Coot model-building tools for molecular graphics journal November 2004
electronic Ligand Builder and Optimization Workbench ( eLBOW ): a tool for ligand coordinate and restraint generation journal September 2009
MolProbity : all-atom structure validation for macromolecular crystallography journal December 2009
Integration, scaling, space-group assignment and post-refinement journal January 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Mechanisms of coenzyme B12-dependent rearrangements journal February 1985
Metalloprotein entatic control of ligand-metal bonds quantified by ultrafast x-ray spectroscopy journal June 2017
A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme journal September 2018
Site-Directed Mutagenesis of HgcA and HgcB Reveals Amino Acid Residues Important for Mercury Methylation journal February 2015
Synthesis and characterization of inner-sphere substitution products in azide-containing сobalt(III) dioximates journal August 2016
De Novo Design and Structural Characterization of Proteins and Metalloproteins journal June 1999
Solution NMR studies of periplasmic binding proteins and their interaction partners journal April 2011
The Use of Circular Dichroism in the Investigation of Protein Structure and Function journal December 2000
Collaboration gets the most out of software journal September 2013

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