Ubiquilin 2 modulates ALS/FTD-linked FUS–RNA complex dynamics and stress granule formation
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journal
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November 2018 |
Interplay between Short-Range Attraction and Long-Range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein–RNA Complexes
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journal
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August 2019 |
Reentrant Phase Transition Drives Dynamic Substructure Formation in Ribonucleoprotein Droplets
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journal
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June 2017 |
Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting.
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journal
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January 1996 |
Branching via K11 and K48 Bestows Ubiquitin Chains with a Unique Interdomain Interface and Enhanced Affinity for Proteasomal Subunit Rpn1
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journal
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January 2020 |
Calculations and Publication-Quality Illustrations for Analytical Ultracentrifugation Data
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book
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January 2015 |
Multi-Signal Sedimentation Velocity Analysis with Mass Conservation for Determining the Stoichiometry of Protein Complexes
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journal
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May 2013 |
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
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journal
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July 2010 |
Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
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journal
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June 2013 |
PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation
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journal
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September 2018 |
High-Yield Expression in Escherichia coli and Purification of Mouse Ubiquitin-Activating Enzyme E1
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journal
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October 2011 |
Linkage-specific conformational ensembles of non-canonical polyubiquitin chains
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journal
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January 2016 |
Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins
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journal
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March 2016 |
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice
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journal
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July 2015 |
Mutant UBQLN2P497H in motor neurons leads to ALS-like phenotypes and defective autophagy in rats
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journal
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November 2018 |
LASSI: A lattice model for simulating phase transitions of multivalent proteins
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journal
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October 2019 |
Ubiquitin‐Modulated Phase Separation of Shuttle Proteins: Does Condensate Formation Promote Protein Degradation?
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journal
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September 2020 |
Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
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journal
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March 2018 |
ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner
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journal
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June 2019 |
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
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journal
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November 1995 |
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
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journal
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August 2011 |
Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties
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journal
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April 2020 |
Proteasomal and Autophagic Degradation Systems
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journal
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June 2017 |
Crystal Structure and Solution NMR Studies of Lys48-linked Tetraubiquitin at Neutral pH
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journal
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March 2007 |
Self‐assembly of multi‐component mitochondrial nucleoids via phase separation
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journal
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February 2021 |
p62-containing, proteolytically active nuclear condensates, increase the efficiency of the ubiquitin–proteasome system
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journal
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August 2021 |
Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins
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journal
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January 2021 |
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
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journal
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April 2020 |
Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner
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journal
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June 2021 |
The role of ubiquitylation in receptor endocytosis and endosomal sorting
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journal
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January 2012 |
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
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journal
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December 2019 |
The specificity of ubiquitin binding to ubiquilin-1 is regulated by sequences besides its UBA domain
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journal
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October 2019 |
Proteostasis impairment in protein-misfolding and -aggregation diseases
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journal
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September 2014 |
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome
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journal
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August 2016 |
E3-Independent Monoubiquitination of Ubiquitin-Binding Proteins
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journal
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June 2007 |
BioXTAS RAW : improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis
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journal
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September 2017 |
Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools
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journal
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July 2011 |
Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment
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journal
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November 2016 |
The Ubiquitin Code
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journal
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July 2012 |
The Biology of Proteostasis in Aging and Disease
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journal
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June 2015 |
UBQLN proteins in health and disease with a focus on UBQLN2 in ALS/FTD
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journal
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July 2021 |
K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells
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journal
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August 2013 |
Ubiquitin Recognition by the Ubiquitin-associated Domain of p62 Involves a Novel Conformational Switch
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journal
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February 2008 |
Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease
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journal
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May 1988 |
Receptor oligomerization guides pathway choice between proteasomal and autophagic degradation
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journal
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May 2017 |
NMRbox: A Resource for Biomolecular NMR Computation
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journal
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April 2017 |
Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.
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journal
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June 1988 |
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
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journal
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September 2015 |
The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates
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journal
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January 2015 |
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?
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journal
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January 2013 |
Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease
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journal
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March 2019 |
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
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journal
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September 2007 |
Evaluating the stoichiometry of macromolecular complexes using multisignal sedimentation velocity
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journal
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May 2011 |
Cellular ubiquitin pool dynamics and homeostasis
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journal
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September 2014 |
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
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journal
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August 2015 |
Ubiquitin-Dependent Sorting in Endocytosis
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journal
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January 2014 |
Diverse polyubiquitin interaction properties of ubiquitin-associated domains
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journal
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July 2005 |
Why structure and chain length matter: on the biological significance underlying the structural heterogeneity of poly(ADP-ribose)
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journal
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July 2021 |
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection
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journal
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November 2010 |
Polyphasic linkage and the impact of ligand binding on the regulation of biomolecular condensates
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journal
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June 2021 |
Physiological, Pathological, and Targetable Membraneless Organelles in Neurons
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journal
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October 2019 |
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
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journal
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April 2020 |
Fiji: an open-source platform for biological-image analysis
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journal
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June 2012 |
Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling
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journal
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March 2000 |
Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity
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journal
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September 2020 |
Mechanisms and Functions of Spatial Protein Quality Control
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journal
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June 2017 |
Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation
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journal
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March 2018 |
Determination of the regularization parameter in indirect-transform methods using perceptual criteria
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journal
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August 1992 |
Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains: Linkage-specific conformations of polyubiquitin chains
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journal
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September 2004 |
FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates
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journal
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April 2019 |
Structural Properties of Polyubiquitin Chains in Solution
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journal
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December 2002 |
Proteome folding and aggregation
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journal
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April 2012 |
The CCPN data model for NMR spectroscopy: Development of a software pipeline
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journal
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April 2005 |
Two-Dimensional NMR Lineshape Analysis
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journal
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April 2016 |
Using chemical shift perturbation to characterise ligand binding
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journal
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August 2013 |
Ligand-linked phase changes in a biological system: applications to sickle cell hemoglobin.
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journal
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September 1980 |
Rigidity enhances a magic-number effect in polymer phase separation
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journal
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March 2020 |
Single Amino Acid Substitutions in Stickers, but Not Spacers, Substantially Alter UBQLN2 Phase Transitions and Dense Phase Material Properties
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journal
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March 2019 |
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
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journal
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April 2020 |
Stress- and ubiquitylation-dependent phase separation of the proteasome
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journal
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February 2020 |
Ubiquitin chain conformation regulates recognition and activity of interacting proteins
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journal
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December 2012 |
p62 filaments capture and present ubiquitinated cargos for autophagy
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journal
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January 2018 |
Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter
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journal
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January 2018 |
Affinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin Chains
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journal
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March 2008 |
Structure, dynamics and functions of UBQLNs: at the crossroads of protein quality control machinery
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journal
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September 2020 |
The Roles of Ubiquitin-Binding Protein Shuttles in the Degradative Fate of Ubiquitinated Proteins in the Ubiquitin-Proteasome System and Autophagy
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journal
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January 2019 |