Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA

Liu, Yaping; Munsayac, Aldrex; Hall, Ian; Keane, Sarah C.

doi:10.1016/j.jmb.2022.167688

Title: Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA

Journal Article · 01 September 2022 · J. Mol. Biol.

DOI:https://doi.org/10.1016/j.jmb.2022.167688· OSTI ID:1901322

Liu, Yaping; Munsayac, Aldrex; Hall, Ian; Keane, Sarah C.

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; National Institutes of Health (NIH)

OSTI ID:: 1901322

Journal Information:: J. Mol. Biol., Vol. 434, Issue (18)

Country of Publication:: United States

Language:: ENGLISH

References (87)

MicroRNAs: Target Recognition and Regulatory Functions Bartel, David P. Cell, Vol. 136, Issue 2 https://doi.org/10.1016/j.cell.2009.01.002	journal	January 2009
Dysregulation of miRNA and its potential therapeutic application in schizophrenia Cao, Ting; Zhen, Xue-Chu CNS Neuroscience & Therapeutics, Vol. 24, Issue 7 https://doi.org/10.1111/cns.12840	journal	March 2018
Biological principles of microRNA-mediated regulation: shared themes amid diversity Flynt, Alex S.; Lai, Eric C. Nature Reviews Genetics, Vol. 9, Issue 11 https://doi.org/10.1038/nrg2455	journal	November 2008
MicroRNAs in Cancer: Small Molecules With a Huge Impact Iorio, Marilena V.; Croce, Carlo M. Journal of Clinical Oncology, Vol. 27, Issue 34 https://doi.org/10.1200/JCO.2009.24.0317	journal	December 2009
MicroRNAs in Stress Signaling and Human Disease Mendell, Joshua T.; Olson, Eric N. Cell, Vol. 148, Issue 6 https://doi.org/10.1016/j.cell.2012.02.005	journal	March 2012
Long Non-coding RNA Structure and Function: Is There a Link? Zampetaki, Anna; Albrecht, Andreas; Steinhofel, Kathleen Frontiers in Physiology, Vol. 9 https://doi.org/10.3389/fphys.2018.01201	journal	August 2018
Processing of primary microRNAs by the Microprocessor complex Denli, Ahmet M.; Tops, Bastiaan B. J.; Plasterk, Ronald H. A. Nature, Vol. 432, Issue 7014 https://doi.org/10.1038/nature03049	journal	November 2004
The Drosha-DGCR8 complex in primary microRNA processing Han, J. Genes & Development, Vol. 18, Issue 24 https://doi.org/10.1101/gad.1262504	journal	December 2004
MicroRNA biogenesis: coordinated cropping and dicing Kim, V. Narry Nature Reviews Molecular Cell Biology, Vol. 6, Issue 5 https://doi.org/10.1038/nrm1644	journal	May 2005
Role for a bidentate ribonuclease in the initiation step of RNA interference Bernstein, Emily; Caudy, Amy A.; Hammond, Scott M. Nature, Vol. 409, Issue 6818 https://doi.org/10.1038/35053110	journal	January 2001
Nuclear Export of MicroRNA Precursors Lund, Elsebet; Güttinger, Stephan; Calado, Angelo Science, Vol. 303, Issue 5654 https://doi.org/10.1126/science.1090599	journal	January 2004
miRNAs: From Biogenesis to Networks Russo, Giuseppe; Giordano, Antonio Methods in Molecular Biology https://doi.org/10.1007/978-1-60761-175-2_17	book	January 2009
Mechanistic Insights into MicroRNA-Mediated Gene Silencing Duchaine, Thomas F.; Fabian, Marc R. Cold Spring Harbor Perspectives in Biology, Vol. 11, Issue 3 https://doi.org/10.1101/cshperspect.a032771	journal	June 2018
Regulation of mRNA Translation and Stability by microRNAs Fabian, Marc Robert; Sonenberg, Nahum; Filipowicz, Witold Annual Review of Biochemistry, Vol. 79, Issue 1 https://doi.org/10.1146/annurev-biochem-060308-103103	journal	June 2010
Regulation of microRNA biogenesis Ha, Minju; Kim, V. Narry Nature Reviews Molecular Cell Biology, Vol. 15, Issue 8 https://doi.org/10.1038/nrm3838	journal	July 2014
Oncomirs — microRNAs with a role in cancer Esquela-Kerscher, Aurora; Slack, Frank J. Nature Reviews Cancer, Vol. 6, Issue 4 https://doi.org/10.1038/nrc1840	journal	April 2006
Oncogenic Biogenesis of pri-miR-17∼92 Reveals Hierarchy and Competition among Polycistronic MicroRNAs Donayo, Ariel O.; Johnson, Radia M.; Tseng, Hsin-Wei Molecular Cell, Vol. 75, Issue 2 https://doi.org/10.1016/j.molcel.2019.05.033	journal	July 2019
Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters Ventura, Andrea; Young, Amanda G.; Winslow, Monte M. Cell, Vol. 132, Issue 5 https://doi.org/10.1016/j.cell.2008.02.019	journal	March 2008
A Polycistronic MicroRNA Cluster, miR-17-92, Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation Hayashita, Yoji; Osada, Hirotaka; Tatematsu, Yoshio Cancer Research, Vol. 65, Issue 21 https://doi.org/10.1158/0008-5472.CAN-05-2352	journal	November 2005
A microRNA polycistron as a potential human oncogene He, Lin; Thomson, J. Michael; Hemann, Michael T. Nature, Vol. 435, Issue 7043 https://doi.org/10.1038/nature03552	journal	June 2005
Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells Takakura, Shu; Mitsutake, Norisato; Nakashima, Masahiro Cancer Science, Vol. 99, Issue 6 https://doi.org/10.1111/j.1349-7006.2008.00800.x	journal	June 2008
miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer Tsuchida, Akihiko; Ohno, Shinichiro; Wu, Weihong Cancer Science, Vol. 102, Issue 12 https://doi.org/10.1111/j.1349-7006.2011.02081.x	journal	September 2011
A microRNA expression signature of human solid tumors defines cancer gene targets Volinia, Stefano; Calin, George A.; Liu, Chang-Gong Proceedings of the National Academy of Sciences, Vol. 103, Issue 7 https://doi.org/10.1073/pnas.0510565103	journal	February 2006
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster Dews, Michael; Homayouni, Asal; Yu, Duonan Nature Genetics, Vol. 38, Issue 9 https://doi.org/10.1038/ng1855	journal	July 2006
Insights into Regulation of the miR-17-92 Cluster of miRNAs in Cancer Fuziwara, Cesar Seigi; Kimura, Edna Teruko Frontiers in Medicine, Vol. 2 https://doi.org/10.3389/fmed.2015.00064	journal	September 2015
Genetic dissection of the miR-17∼92 cluster of microRNAs in Myc-induced B-cell lymphomas Mu, Ping; Han, Yoon-Chi; Betel, Doron Genes & Development, Vol. 23, Issue 24 https://doi.org/10.1101/gad.1872909	journal	December 2009
A Biogenesis Step Upstream of Microprocessor Controls miR-17∼92 Expression Du, Peng; Wang, Longfei; Sliz, Piotr Cell, Vol. 162, Issue 4 https://doi.org/10.1016/j.cell.2015.07.008	journal	August 2015
A structural map of oncomiR-1 at single-nucleotide resolution Chakraborty, Saikat; Krishnan, Yamuna Nucleic Acids Research, Vol. 45, Issue 16 https://doi.org/10.1093/nar/gkx613	journal	July 2017
c-Myc-regulated microRNAs modulate E2F1 expression O'Donnell, Kathryn A.; Wentzel, Erik A.; Zeller, Karen I. Nature, Vol. 435, Issue 7043 https://doi.org/10.1038/nature03677	journal	June 2005
mir-17-92 : a polycistronic oncomir with pleiotropic functions Olive, Virginie; Li, Qijing; He, Lin Immunological Reviews, Vol. 253, Issue 1 https://doi.org/10.1111/imr.12054	journal	April 2013
Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans de Pontual, Loïc; Yao, Evelyn; Callier, Patrick Nature Genetics, Vol. 43, Issue 10 https://doi.org/10.1038/ng.915	journal	September 2011
The miR-17-92 cluster expands multipotent hematopoietic progenitors whereas imbalanced expression of its individual oncogenic miRNAs promotes leukemia in mice Li, Yanmei; Vecchiarelli-Federico, Laura M.; Li, You-Jun Blood, Vol. 119, Issue 19 https://doi.org/10.1182/blood-2011-09-378687	journal	May 2012
MiR-92a Family: A Novel Diagnostic Biomarker and Potential Therapeutic Target in Human Cancers Jiang, Min; Li, Xuelian; Quan, Xiaowei Frontiers in Molecular Biosciences, Vol. 6 https://doi.org/10.3389/fmolb.2019.00098	journal	October 2019
Good or not good: Role of miR-18a in cancer biology Kolenda, Tomasz; Guglas, Kacper; Kopczyńska, Magda Reports of Practical Oncology & Radiotherapy, Vol. 25, Issue 5 https://doi.org/10.1016/j.rpor.2020.07.006	journal	September 2020
MicroRNA-18a inhibits ovarian cancer growth via directly targeting TRIAP1 and IPMK Liu, Ping; Qi, Xiaorong; Bian, Ce Oncology Letters, Vol. 13, Issue 6 https://doi.org/10.3892/ol.2017.5961	journal	March 2017
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α Chen, Xu; Wu, Lei; Li, Dezhi Cancer Medicine, Vol. 7, Issue 8 https://doi.org/10.1002/cam4.1527	journal	June 2018
Pri-miR-17-92a transcript folds into a tertiary structure and autoregulates its processing Chakraborty, Saikat; Mehtab, Shabana; Patwardhan, Anand RNA, Vol. 18, Issue 5 https://doi.org/10.1261/rna.031039.111	journal	March 2012
Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis Chaulk, Steven G.; Thede, Gina L.; Kent, Oliver A. RNA Biology, Vol. 8, Issue 6 https://doi.org/10.4161/rna.8.6.17410	journal	November 2011
MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17∼92 microRNA cluster Chaulk, Steven G.; Xu, Zhizhong; Glover, Mark J. N. Nucleic Acids Research, Vol. 42, Issue 8 https://doi.org/10.1093/nar/gku133	journal	February 2014
A Network of Heterogeneous Hydrogen Bonds in GNRA Tetraloops Jucker, Fiona M.; Heus, Hans A.; Yip, Ping F. Journal of Molecular Biology, Vol. 264, Issue 5 https://doi.org/10.1006/jmbi.1996.0690	journal	December 1996
NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database Liu, Yaping; Kotar, Anita; Hodges, Tracy L. Biomolecular NMR Assignments, Vol. 15, Issue 2 https://doi.org/10.1007/s12104-021-10049-0	journal	August 2021
An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA^, Chen, Gang; Kennedy, Scott D.; Qiao, Jing Biochemistry, Vol. 45, Issue 22 https://doi.org/10.1021/bi0524464	journal	May 2006
Visualizing a protonated RNA state that modulates microRNA-21 maturation Baisden, Jared T.; Boyer, Joshua A.; Zhao, Bo Nature Chemical Biology, Vol. 17, Issue 1 https://doi.org/10.1038/s41589-020-00667-5	journal	October 2020
pH dependence of C•A, G•A and A•A mismatches in the stem of precursor microRNA-31 Kotar, Anita; Ma, Sicong; Keane, Sarah C. Biophysical Chemistry, Vol. 283 https://doi.org/10.1016/j.bpc.2022.106763	journal	April 2022
Solution Structure of the HIV-1 Exon Splicing Silencer 3 Levengood, Jeffrey D.; Rollins, Carrie; Mishler, Clay H. J. Journal of Molecular Biology, Vol. 415, Issue 4 https://doi.org/10.1016/j.jmb.2011.11.034	journal	January 2012
A ph controlled conformational switch in the cleavage site of the VS ribozyme substrate RNA 1 1Edited by I. Tinoco Flinders, Jeremy; Dieckmann, Thorsten Journal of Molecular Biology, Vol. 308, Issue 4 https://doi.org/10.1006/jmbi.2001.4627	journal	May 2001
Unusual Dynamics and pK_a Shift at the Active Site of a Lead-Dependent Ribozyme Legault, Pascale; Pardi, Arthur Journal of the American Chemical Society, Vol. 119, Issue 28 https://doi.org/10.1021/ja9640051	journal	July 1997
Protonation-Dependent Base Flipping at Neutral pH in the Catalytic Triad of a Self-Splicing Bacterial Group II Intron Pechlaner, Maria; Donghi, Daniela; Zelenay, Veronika Angewandte Chemie International Edition, Vol. 54, Issue 33 https://doi.org/10.1002/anie.201504014	journal	June 2015
Protonation of non-Watson–Crick base pairs and encapsidation of turnip yellow mosaic virus RNA Bink, Hugo H. J.; Hellendoorn, Koen; van der Meulen, Jannes Proceedings of the National Academy of Sciences, Vol. 99, Issue 21 https://doi.org/10.1073/pnas.202287499	journal	October 2002
An equilibrium-dependent retroviral mRNA switch regulates translational recoding Houck-Loomis, Brian; Durney, Michael A.; Salguero, Carolina Nature, Vol. 480, Issue 7378 https://doi.org/10.1038/nature10657	journal	November 2011
Driving Forces for Nucleic Acid pK_a Shifting in an A⁺·C Wobble: Effects of Helix Position, Temperature, and Ionic Strength Siegfried, Nathan A.; O’Hare, Bernie; Bevilacqua, Philip C. Biochemistry, Vol. 49, Issue 15 https://doi.org/10.1021/bi901920g	journal	March 2010
Through-Bond Correlation of Adenine Protons in a 13C-Labeled Ribozyme Legault, Pascale; Farmer, Bennett T.; Mueller, Luciano Journal of the American Chemical Society, Vol. 116, Issue 5 https://doi.org/10.1021/ja00084a094	journal	March 1994
Protonation Studies of Modified Adenine and Adenine Nucleotides by Theoretical Calculations and ¹⁵N NMR Major, Dan T.; Laxer, Avital; Fischer, Bilha The Journal of Organic Chemistry, Vol. 67, Issue 3 https://doi.org/10.1021/jo0107554	journal	January 2002
Calculation of pKas in RNA: On the Structural Origins and Functional Roles of Protonated Nucleotides Tang, Christopher L.; Alexov, Emil; Pyle, Anna Marie Journal of Molecular Biology, Vol. 366, Issue 5 https://doi.org/10.1016/j.jmb.2006.12.001	journal	March 2007
RNA Folding: Conformational Statistics, Folding Kinetics, and Ion Electrostatics Chen, Shi-Jie Annual Review of Biophysics, Vol. 37, Issue 1 https://doi.org/10.1146/annurev.biophys.37.032807.125957	journal	June 2008
On the stability of nucleic acid structures in solution: enthalpy - entropy compensations, internal rotations and reversibility Searle, Mark S.; Williams, Dudley H. Nucleic Acids Research, Vol. 21, Issue 9 https://doi.org/10.1093/nar/21.9.2051	journal	January 1993
A Transient and Flexible Cation−π Interaction Promotes Hydrolysis of Nucleic Acids in DNA and RNA Nucleases Genna, Vito; Marcia, Marco; De Vivo, Marco Journal of the American Chemical Society, Vol. 141, Issue 27 https://doi.org/10.1021/jacs.9b03663	journal	June 2019
Analysis of cation–π interactions to the structural stability of RNA binding proteins Chakkaravarthi, S.; Gromiha, M. Michael Polymer, Vol. 47, Issue 2 https://doi.org/10.1016/j.polymer.2005.11.059	journal	January 2006
Divalent Cations Stabilize Unstacked Conformations of DNA and RNA by Interacting with Base Π Systems McFail-Isom, Lori; Shui, Xiuqi; Williams, Loren Dean Biochemistry, Vol. 37, Issue 49 https://doi.org/10.1021/bi982201+	journal	November 1998
Cooperative Interactions in the Hammerhead Ribozyme Drive pK_a Shifting of G12 and Its Stacked Base C17 Frankel, Erica A.; Strulson, Christopher A.; Keating, Christine D. Biochemistry, Vol. 56, Issue 20 https://doi.org/10.1021/acs.biochem.7b00174	journal	May 2017
Two Active Site Divalent Ions in the Crystal Structure of the Hammerhead Ribozyme Bound to a Transition State Analogue Mir, Aamir; Golden, Barbara L. Biochemistry, Vol. 55, Issue 4 https://doi.org/10.1021/acs.biochem.5b01139	journal	January 2016
Structural Basis for Ligand Binding to the Guanidine-I Riboswitch Reiss, Caroline W.; Xiong, Yong; Strobel, Scott A. Structure, Vol. 25, Issue 1 https://doi.org/10.1016/j.str.2016.11.020	journal	January 2017
Structural basis for ligand binding to the guanidine-II riboswitch Reiss, Caroline W.; Strobel, Scott A. RNA, Vol. 23, Issue 9 https://doi.org/10.1261/rna.061804.117	journal	June 2017
A Single Adenosine with a Neutral pKa in the Ribosomal Peptidyl Transferase Center Muth, G. W. Science, Vol. 289, Issue 5481 https://doi.org/10.1126/science.289.5481.947	journal	August 2000
A simple and efficient method to reduce nontemplated nucleotide addition at the 3′ terminus of RNAs transcribed by T7 RNA polymerase Kao, C.; Zheng, M.; RÜDisser, S. RNA, Vol. 5, Issue 9 https://doi.org/10.1017/S1355838299991033	journal	September 1999
Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies Buchmueller, K. L. Nucleic Acids Research, Vol. 32, Issue 22 https://doi.org/10.1093/nar/gnh182	journal	December 2004
NMRFx Processor: a cross-platform NMR data processing program Norris, Michael; Fetler, Bayard; Marchant, Jan Journal of Biomolecular NMR, Vol. 65, Issue 3-4 https://doi.org/10.1007/s10858-016-0049-6	journal	July 2016
NMRPipe: A multidimensional spectral processing system based on UNIX pipes Delaglio, Frank; Grzesiek, Stephan; Vuister, GeertenW. Journal of Biomolecular NMR, Vol. 6, Issue 3 https://doi.org/10.1007/BF00197809	journal	November 1995
NMR View: A computer program for the visualization and analysis of NMR data Johnson, Bruce A.; Blevins, Richard A. Journal of Biomolecular NMR, Vol. 4, Issue 5 https://doi.org/10.1007/BF00404272	journal	September 1994
1H, 13C and 15N chemical shift referencing in biomolecular NMR Wishart, David S.; Bigam, Colin G.; Yao, Jian Journal of Biomolecular NMR, Vol. 6, Issue 2 https://doi.org/10.1007/BF00211777	journal	September 1995
The CLIP/CLAP-HSQC: Pure absorptive spectra for the measurement of one-bond couplings Enthart, Andreas; Freudenberger, J. Christoph; Furrer, Julien Journal of Magnetic Resonance, Vol. 192, Issue 2 https://doi.org/10.1016/j.jmr.2008.03.009	journal	June 2008
Evaluation of Cross-Correlation Effects and Measurement of One-Bond Couplings in Proteins with Short Transverse Relaxation Times Kontaxis, Georg; Clore, G. Marius; Bax, Ad Journal of Magnetic Resonance, Vol. 143, Issue 1 https://doi.org/10.1006/jmre.1999.1979	journal	March 2000
Improved accuracy of 15N–1H scalar and residual dipolar couplings from gradient-enhanced IPAP-HSQC experiments on protonated proteins Yao, Lishan; Ying, Jinfa; Bax, Ad Journal of Biomolecular NMR, Vol. 43, Issue 3 https://doi.org/10.1007/s10858-009-9299-x	journal	February 2009
15N and 13C- SOFAST-HMQC editing enhances 3D-NOESY sensitivity in highly deuterated, selectively [1H,13C]-labeled proteins Rossi, Paolo; Xia, Youlin; Khanra, Nandish Journal of Biomolecular NMR, Vol. 66, Issue 4 https://doi.org/10.1007/s10858-016-0074-5	journal	November 2016
Cooperative RNA Folding under Cellular Conditions Arises From Both Tertiary Structure Stabilization and Secondary Structure Destabilization Leamy, Kathleen A.; Yennawar, Neela H.; Bevilacqua, Philip C. Biochemistry, Vol. 56, Issue 27 https://doi.org/10.1021/acs.biochem.7b00325	journal	June 2017
Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment Kirby, Nigel; Cowieson, Nathan; Hawley, Adrian M. Acta Crystallographica Section D Structural Biology, Vol. 72, Issue 12 https://doi.org/10.1107/S2059798316017174	journal	November 2016
BioXTAS RAW : improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis Hopkins, Jesse Bennett; Gillilan, Richard E.; Skou, Soren Journal of Applied Crystallography, Vol. 50, Issue 5 https://doi.org/10.1107/S1600576717011438	journal	September 2017
GNOM – a program package for small-angle scattering data processing Semenyuk, A. V.; Svergun, D. I. Journal of Applied Crystallography, Vol. 24, Issue 5 https://doi.org/10.1107/S002188989100081X	journal	October 1991
Ab initio electron density determination directly from solution scattering data Grant, Thomas D. Nature Methods, Vol. 15, Issue 3 https://doi.org/10.1038/nmeth.4581	journal	January 2018
Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments Schneidman-Duhovny, Dina; Hammel, Michal; Tainer, John A. Biophysical Journal, Vol. 105, Issue 4 https://doi.org/10.1016/j.bpj.2013.07.020	journal	August 2013
FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles Schneidman-Duhovny, Dina; Hammel, Michal; Tainer, John A. Nucleic Acids Research, Vol. 44, Issue W1 https://doi.org/10.1093/nar/gkw389	journal	May 2016
Major groove width variations in RNA structures determined by NMR and impact of 13C residual chemical shift anisotropy and 1H–13C residual dipolar coupling on refinement Tolbert, Blanton S.; Miyazaki, Yasuyuki; Barton, Shawn Journal of Biomolecular NMR, Vol. 47, Issue 3 https://doi.org/10.1007/s10858-010-9424-x	journal	June 2010
The Amber biomolecular simulation programs Case, David A.; Cheatham, Thomas E.; Darden, Tom Journal of Computational Chemistry, Vol. 26, Issue 16 https://doi.org/10.1002/jcc.20290	journal	January 2005
Benchmarking AMBER Force Fields for RNA: Comparisons to NMR Spectra for Single-Stranded r(GACC) Are Improved by Revised χ Torsions Yildirim, Ilyas; Stern, Harry A.; Tubbs, Jason D. The Journal of Physical Chemistry B, Vol. 115, Issue 29 https://doi.org/10.1021/jp2016006	journal	July 2011
Refinement of the Cornell et al. Nucleic Acids Force Field Based on Reference Quantum Chemical Calculations of Glycosidic Torsion Profiles Zgarbová, Marie; Otyepka, Michal; Šponer, Jiří Journal of Chemical Theory and Computation, Vol. 7, Issue 9 https://doi.org/10.1021/ct200162x	journal	August 2011
Generalized Born Model with a Simple, Robust Molecular Volume Correction Mongan, John; Simmerling, Carlos; McCammon, J. Andrew Journal of Chemical Theory and Computation, Vol. 3, Issue 1 https://doi.org/10.1021/ct600085e	journal	December 2006
RNA2Drawer: geometrically strict drawing of nucleic acid structures with graphical structure editing and highlighting of complementary subsequences Johnson, Philip Z.; Kasprzak, Wojciech K.; Shapiro, Bruce A. RNA Biology, Vol. 16, Issue 12 https://doi.org/10.1080/15476286.2019.1659081	journal	August 2019

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