Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X In

Lowe, Martin A.; Cardenas, Alvaro; Valentin, Jean-Pierre; Zhu, Zhaoning; Abendroth, Jan; Castro, Jose L.; Class, Reiner; Delaunois, Annie; Fleurance, Renaud; Gerets, Helga; Gryshkova, Vitalina; King, Lloyd; Lorimer, Donald D.; MacCoss, Malcolm; Rowley, Julian H.; Rosseels, Marie-Luce; Royer, Leandro; Taylor, Richard D.; Wong, Melanie; Zaccheo, Oliver; Chavan, Vishal P.; Ghule, Gokul A.; Tapkir, Bapusaheb K.; Burrows, Jeremy N.; Duffey, Maelle; Rottmann, Matthias; Wittlin, Sergio; Angulo-Barturen, I?igo; Jimenez-Diaz, Maria Belen; Striepen, Josefine; Fairhurst, Kate J.; Yeo, Tomas; Fidock, David A.; Cowman, Alan F.; Favuzza, Paola; Crespo-Fernandez, Benigno; Gamo, Francisco Javier; Goldberg, Daniel E.; Soldati-Favre, Dominique; Laleu, Benoit; de Haro, Teresa

doi:10.1021/acs.jmedchem.2c01336

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X In

Journal Article · 01 October 2022 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.2c01336· OSTI ID:1901314

Lowe, Martin A.; Cardenas, Alvaro; Valentin, Jean-Pierre; Zhu, Zhaoning; Abendroth, Jan; Castro, Jose L.; Class, Reiner; Delaunois, Annie; Fleurance, Renaud; Gerets, Helga; Gryshkova, Vitalina; King, Lloyd; Lorimer, Donald D.; MacCoss, Malcolm; Rowley, Julian H.; Rosseels, Marie-Luce; Royer, Leandro; Taylor, Richard D.; Wong, Melanie; Zaccheo, Oliver more »

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1901314

Journal Information:: J. Med. Chem., Journal Name: J. Med. Chem. Journal Issue: (20) Vol. 65

Country of Publication:: United States

Language:: ENGLISH

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