Structural and genetic basis for development of broadly neutralizing influenza antibodies
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journal
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August 2012 |
Complement Is Activated by IgG Hexamers Assembled at the Cell Surface
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journal
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March 2014 |
Next generation antibody drugs: pursuit of the 'high-hanging fruit'
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journal
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December 2017 |
‘Knobs-into-holes’ engineering of antibody C H 3 domains for heavy chain heterodimerization
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journal
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January 1996 |
Alternative molecular formats and therapeutic applications for bispecific antibodies
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journal
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October 2015 |
High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR
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journal
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November 2000 |
Lack of Fucose on Human IgG1 N -Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity
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journal
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May 2002 |
Engineered antibody Fc variants with enhanced effector function
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journal
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March 2006 |
Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells
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journal
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August 2008 |
Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcγRIIb with Fc-engineered antibodies
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journal
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September 2008 |
Fc Optimization of Therapeutic Antibodies Enhances Their Ability to Kill Tumor Cells In vitro and Controls Tumor Expansion In vivo via Low-Affinity Activating Fc Receptors
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journal
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September 2007 |
Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity
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journal
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February 1999 |
Engineered antibody Fc variant with selectively enhanced Fc RIIb binding over both Fc RIIaR131 and Fc RIIaH131
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journal
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June 2013 |
Novel asymmetrically engineered antibody Fc variant with superior FcγR binding affinity and specificity compared with afucosylated Fc variant
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journal
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March 2013 |
Defucosylated Chimeric Anti-CC Chemokine Receptor 4 IgG1 with Enhanced Antibody-Dependent Cellular Cytotoxicity Shows Potent Therapeutic Activity to T-Cell Leukemia and Lymphoma
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journal
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March 2004 |
Engineered Antibodies with Increased Activity to Recruit Complement
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journal
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February 2001 |
Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions
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journal
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March 2010 |
An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence
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journal
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November 2019 |
Enhanced antibody half-life improves in vivo activity
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journal
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January 2010 |
Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn)
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journal
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June 2006 |
Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer
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journal
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April 2021 |
Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties
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journal
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November 2011 |
Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma
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journal
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February 2019 |
A Review of Obinutuzumab (GA101), a Novel Type II Anti-CD20 Monoclonal Antibody, for the Treatment of Patients with B-Cell Malignancies
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journal
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December 2016 |
Benralizumab – a humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity – a novel approach for the treatment of asthma
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journal
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December 2011 |
MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
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journal
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June 2010 |
Amivantamab (JNJ-61186372), an Fc Enhanced EGFR/cMet Bispecific Antibody, Induces Receptor Downmodulation and Antitumor Activity by Monocyte/Macrophage Trogocytosis
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journal
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August 2020 |
A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults
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journal
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December 2013 |
Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults
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journal
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January 2018 |
Tafasitamab for the treatment of relapsed or refractory diffuse large B-cell lymphoma
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journal
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February 2021 |
Pharmacokinetic and pharmacodynamic effects of ravulizumab and eculizumab on complement component 5 in adults with paroxysmal nocturnal haemoglobinuria: results of two phase 3 randomised, multicentre studies
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journal
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May 2020 |
Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action
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journal
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April 2018 |
Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design
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journal
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August 2001 |
Understanding the fabric of protein crystals: computational classification of biological interfaces and crystal contacts
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journal
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October 2015 |
Distinguishing crystallographic from biological interfaces in protein complexes: role of intermolecular contacts and energetics for classification
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journal
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November 2018 |
TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2
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journal
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December 2015 |
Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
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journal
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May 2008 |
SAbDab: the structural antibody database
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journal
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November 2013 |
Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool
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journal
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June 2001 |
Inference of Macromolecular Assemblies from Crystalline State
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journal
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September 2007 |
A structural dissection of large protein-protein crystal packing contacts
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journal
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September 2015 |
Humanization of an anti-p185HER2 antibody for human cancer therapy.
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journal
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May 1992 |
Principles and engineering of antibody folding and assembly
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journal
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November 2014 |
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members
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journal
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June 2019 |
Transient protein-protein interactions
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journal
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June 2011 |
Design of Multi-Specificity in Protein Interfaces
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journal
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August 2007 |
Proteins evolve on the edge of supramolecular self-assembly
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journal
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August 2017 |
FDA approves 100th monoclonal antibody product
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journal
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May 2021 |
Secondary structure based analysis and classification of biological interfaces: identification of binding motifs in protein–protein interactions
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journal
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May 2007 |
Structures of ParB bound to DNA reveal mechanism of partition complex formation
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journal
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November 2005 |
Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein
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journal
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May 1995 |
Evolutionary changes to transthyretin: structure-function relationships
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journal
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September 2009 |
The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue
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journal
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June 1995 |
Computational design of a symmetric homodimer using -strand assembly
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journal
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December 2011 |
The Supramolecular Chemistry of β-Sheets
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journal
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April 2013 |
Biology of Amyloid: Structure, Function, and Regulation
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journal
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October 2010 |
Natural -sheet proteins use negative design to avoid edge-to-edge aggregation
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journal
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March 2002 |
The fundamentals of protein folding: bringing together theory and experiment
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journal
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February 1999 |
Developability Assessment During the Selection of Novel Therapeutic Antibodies
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journal
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June 2015 |
Prediction and Reduction of the Aggregation of Monoclonal Antibodies
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journal
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April 2017 |
Antibody Aggregation: Insights from Sequence and Structure
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journal
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September 2016 |
Potential aggregation prone regions in biotherapeutics
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journal
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May 2009 |
Structure of the secretory immunoglobulin A core
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journal
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February 2020 |
Structural insights into immunoglobulin M
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journal
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February 2020 |
Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition
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journal
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June 2003 |
Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12
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journal
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December 2013 |
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies
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journal
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May 2021 |
Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11
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journal
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November 2020 |
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab
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journal
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February 2020 |
Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2
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journal
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June 2022 |
Formation of biological condensates via phase separation: Characteristics, analytical methods, and physiological implications
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journal
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August 2019 |
Direct observation of structure and dynamics during phase separation of an elastomeric protein
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journal
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May 2017 |
Liquid-liquid phase separation and extracellular multivalent interactions in the tale of galectin-3
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journal
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March 2020 |
IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T cell receptors, MHC, IgSF and MhcSF
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journal
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November 2009 |
IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data
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journal
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January 2004 |
Structure-based approach to the prediction of disulfide bonds in proteins
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journal
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May 2014 |
Data processing and analysis with the autoPROC toolbox
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journal
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March 2011 |
XDS
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journal
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January 2010 |
Phaser crystallographic software
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journal
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July 2007 |
Coot model-building tools for molecular graphics
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journal
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November 2004 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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journal
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January 2010 |
Refinement of Macromolecular Structures by the Maximum-Likelihood Method
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journal
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May 1997 |