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Cardiac myosin filaments are directly regulated by calcium

Journal Article · · J. Gen. Physiol.
Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; NIGMS; NIH
OSTI ID:
1901179
Journal Information:
J. Gen. Physiol., Journal Name: J. Gen. Physiol. Journal Issue: (12) Vol. 154
Country of Publication:
United States
Language:
ENGLISH

References (53)

The low-angle X-ray diagram of vertebrate striated muscle and its behaviour during contraction and rigor journal December 1967
The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations journal May 2017
Regulation by Myosin: How Calcium Regulates Some Myosins, Past and Present book January 2007
Calmodulin and the regulation of smooth muscle contraction journal January 1994
Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle journal September 2018
Small Angle X-ray Diffraction as a Tool for Structural Characterization of Muscle Disease journal March 2022
Structural basis of the super- and hyper-relaxed states of myosin II journal December 2021
Stress-dependent activation of myosin in the heart requires thin filament activation and thick filament mechanosensing journal April 2021
Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments journal November 2015
Myofibril orientation as a metric for characterizing heart disease journal February 2022
X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle journal December 1994
The structure of the native cardiac thin filament at systolic Ca 2+ levels journal March 2021
Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling journal June 2017
A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice journal February 2016
Inotropic interventions do not change the resting state of myosin motors during cardiac diastole journal December 2018
The Super-Relaxed State and Length Dependent Activation in Porcine Myocardium journal September 2021
Order-disorder structural transitions in synthetic filaments of fast and slow skeletal muscle myosins under relaxing and activating conditions. journal December 2000
X-ray evidence for radial cross-bridge movement and for the sliding filament model in actively contracting skeletal muscle journal July 1973
Myosin Head Configurations in Resting and Contracting Murine Skeletal Muscle journal September 2018
Systolic [Ca 2+ ] i regulates diastolic levels in rat ventricular myocytes: Control of diastolic [Ca 2+ ] i in heart journal July 2017
Response to: Thick Filament Length Changes in Muscle Have Both Elastic and Structural Components journal March 2019
X-Ray Diffraction Studies of the Heart journal June 1980
biocatiit/musclex: v1.23.2 software May 2024
Calcium-dependent molecular spring elements in the giant protein titin journal October 2003
Regulatory Light Chains in Cardiac Development and Disease journal April 2021
Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscle journal June 2011
Analysing force–pCa curves journal May 2010
Recent improvements in small angle x-ray diffraction for the study of muscle physiology journal September 2006
Myosin ATP turnover rate is a mechanism involved in thermogenesis in resting skeletal muscle fibers journal December 2009
Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers journal August 2018
Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2′‐deoxy‐ATP journal September 2020
The Ins and Outs of Mitochondrial Calcium journal May 2015
Ca2+-induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction journal March 1994
Thin Filament-Mediated Regulation of Cardiac Contraction journal October 1996
Calcium and Excitation-Contraction Coupling in the Heart journal July 2017
Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations journal February 2019
The BioCAT undulator beamline 18ID: a facility for biological non-crystalline diffraction and X-ray absorption spectroscopy at the Advanced Photon Source journal August 2004
Evidence for structural changes in vertebrate thick filaments induced by calcium journal September 1974
The role of the myosin ATPase activity in adaptive thermogenesis by skeletal muscle journal March 2011
Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems journal January 2021
Thick Filament Length Changes in Muscle Have Both Elastic and Structural Components journal March 2019
Small Molecules Acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases journal December 2020
The Regulation of Rabbit Skeletal Muscle Contraction journal August 1971
Structural Basis of the Cross-Striations in Muscle journal September 1953
Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins journal February 2016
A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle journal August 2017
The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms journal May 2020
Myosin filament activation in the heart is tuned to the mechanical task journal March 2017
Multiscale modeling of twitch contractions in cardiac trabeculae journal January 2021
Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin journal February 2022
To lie or not to lie: Super-relaxing with myosins journal February 2021
Thick-Filament Extensibility in Intact Skeletal Muscle journal October 2018
Myosin light chain 2 modulates calcium-sensitive cross-bridge transitions in vertebrate skeletal muscle journal August 1992

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