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Identification of a Cysteine Residue Essential for Activity of Protein Farnesyltransferase
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November 1996 |
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A titanic drug resistance threat in Cryptococcus neoformans
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December 2019 |
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Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes
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June 2004 |
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Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens
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October 2011 |
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Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
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December 2017 |
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Describing Complex Structure-Function Relationships in Biomolecules at Equilibrium
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March 2020 |
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Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution
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March 1997 |
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Exploring the tetrahydroisoquinoline thiohydantoin scaffold blockade the androgen receptor as potent anti-prostate cancer agents
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January 2018 |
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Simultaneous determination of farnesyl and geranylgeranyl pyrophosphate levels in cultured cells
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January 2005 |
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NIH Image to ImageJ: 25 years of image analysis
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June 2012 |
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Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia
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February 2016 |
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Crystal Structure of Farnesyl Protein Transferase Complexed with a CaaX Peptide and Farnesyl Diphosphate Analogue
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November 1998 |
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Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate
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November 2008 |
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Crystal structures of the fungal pathogenAspergillus fumigatusprotein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design
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January 2014 |
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Synthesis, in Vitro Evaluation, and Radiolabeling of Fluorinated Puromycin Analogues: Potential Candidates for PET Imaging of Protein Synthesis
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October 2016 |
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Ras signalling in pathogenic yeasts
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February 2018 |
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Susceptibility of Cryptococcus neoformans Biofilms to Antifungal Agents In Vitro
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March 2006 |
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Microwave-assisted benzyl mono- and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachloride
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January 2011 |
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Subcellular Localization Directs Signaling Specificity of the Cryptococcus neoformans Ras1 Protein
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February 2009 |
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The RAM1 gene encoding a protein-farnesyltransferase β-subunit homologue is essential in Cryptococcus neoformans
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June 2004 |
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Protein Prenylation: Molecular Mechanisms and Functional Consequences
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June 1996 |
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Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
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August 1995 |
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Antifungal drug resistance: evolution, mechanisms and impact
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October 2018 |
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Aryloxy substituted N-arylpiperazinones as dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I
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June 2001 |
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Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis
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April 2016 |
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A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures
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July 1962 |
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Anions Modulate the Potency of Geranylgeranyl-Protein Transferase I Inhibitors
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January 2001 |
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Cocrystal Structure of Protein Farnesyltransferase Complexed with a Farnesyl Diphosphate Substrate,
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June 1998 |
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Synergy between Anions and Farnesyldiphosphate Competitive Inhibitors of Farnesyl:Protein Transferase
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journal
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July 1997 |
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Measuring enzyme activities under standardized in vivo-like conditions for systems biology: Standardized enzyme assays for systems biology
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January 2010 |
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TheAspergillus fumigatusfarnesyltransferase β-subunit, RamA, mediates growth, virulence, and antifungal susceptibility
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June 2017 |
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N-Arylpiperazinone Inhibitors of Farnesyltransferase: Discovery and Biological Activity
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September 1999 |
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Treatment strategies for cryptococcal infection: challenges, advances and future outlook
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February 2021 |
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Mutational Analysis of Conserved Residues of the ॆ-Subunit of Human Farnesyl:Protein Transferase
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October 1997 |
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Reaction path of protein farnesyltransferase at atomic resolution
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journal
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October 2002 |
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Efficient synthesis of N-arylpiperazinones via a selective intramolecular Mitsunobu cyclodehydration
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October 1998 |
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Structure of mammalian protein geranylgeranyltransferase type-I
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November 2003 |
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The Halogen Bond
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January 2016 |
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Sexual Cycle of Cryptococcus neoformans var. grubii and Virulence of Congenic a and α Isolates
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September 2003 |
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The Still Underestimated Problem of Fungal Diseases Worldwide
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February 2019 |
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A systematic review of fluconazole resistance in clinical isolates ofCryptococcusspecies
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February 2018 |
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Prospects for Antibacterial Discovery and Development
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December 2021 |
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The basis for K-Ras4B binding specificity to protein farnesyl-transferase revealed by 2 Å resolution ternary complex structures
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February 2000 |
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Analyzing Fission Yeast Multidrug Resistance Mechanisms to Develop a Genetically Tractable Model System for Chemical Biology
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July 2012 |
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Structurally Simple Inhibitors of Lanosterol 14α-Demethylase Are Efficacious In a Rodent Model of Acute Chagas Disease
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May 2009 |
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Crystal Structures of Staphylococcus aureus Methionine Aminopeptidase Complexed with Keto Heterocycle and Aminoketone Inhibitors Reveal the Formation of a Tetrahedral Intermediate
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journal
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February 2004 |
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Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA
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March 1993 |
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Potent and Selective Farnesyl Transferase Inhibitors
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journal
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December 2004 |