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Title: Structures of topoisomerase V in complex with DNA reveal unusual DNA-binding mode and novel relaxa

Journal Article · · eLIFE J.
DOI:https://doi.org/10.7554/eLife.72702· OSTI ID:1901099

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; NCI; NIGMS
OSTI ID:
1901099
Journal Information:
eLIFE J., Vol. 11
Country of Publication:
United States
Language:
ENGLISH

References (53)

PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals journal June 2016
Electrostatics of nanosystems: Application to microtubules and the ribosome journal August 2001
A type IB topoisomerase with DNA repair activities journal May 2001
DNA Topoisomerases journal October 2015
Structure, Molecular Mechanisms, and Evolutionary Relationships in DNA Topoisomerases journal June 2004
MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes journal July 2004
The helix-hairpin-helix DNA-binding motif: a structural basis for non- sequence-specific recognition of DNA journal July 1996
Coot model-building tools for molecular graphics journal November 2004
Features and development of Coot journal March 2010
How good are my data and what is the resolution? journal June 2013
HullRad: Fast Calculations of Folded and Disordered Protein and Nucleic Acid Hydrodynamic Properties journal February 2018
Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography journal July 2013
DNA topoisomerase V: a new fold of mysterious origin journal June 2006
Origin and evolution of DNA topoisomerases journal April 2007
Replication Clamps and Clamp Loaders journal April 2013
Highly accurate protein structure prediction with AlphaFold journal July 2021
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants journal December 1993
Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB journal March 2005
Inference of Macromolecular Assemblies from Crystalline State journal September 2007
Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I journal January 1994
Preferential binding of human topoisomerase I to superhelical DNA. journal November 1995
The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target journal January 2012
Phaser crystallographic software journal July 2007
Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion journal October 2005
Structure and mechanism of nucleases regulated by SLX4 journal February 2016
Crystal Structure of a Bacterial Topoisomerase IB in Complex with DNA Reveals a Secondary DNA Binding Site journal June 2010
Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A journal May 1991
Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers journal September 1993
Helix–hairpin–helix motifs confer salt resistance and processivity on chimeric DNA polymerases journal October 2002
Structural Basis for Specificity in the Poxvirus Topoisomerase journal August 2006
UCSF Chimera?A visualization system for exploratory research and analysis journal January 2004
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs journal May 2010
Roles of eukaryotic topoisomerases in transcription, replication and genomic stability journal September 2016
Structures of Minimal Catalytic Fragments of Topoisomerase V Reveals Conformational Changes Relevant for DNA Binding journal July 2010
Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies journal November 2012
Biochemical Characterization of the Topoisomerase Domain of Methanopyrus kandleri Topoisomerase V journal August 2014
Methanopyrus kandleritopoisomerase V contains three distinct AP lyase active sites in addition to the topoisomerase active site journal February 2016
Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA journal March 1998
A Bayesian approach to high-resolution X-ray crystallography: accurate density studies with program BUSTER journal August 1996
Common fold in helix-hairpin-helix proteins journal July 2000
Intramolecular synapsis of duplex DNA by vaccinia topoisomerase journal November 1997
DNA topoisomerase V is a relative of eukaryotic topoisomerase I from a hyperthermophilic prokaryote journal August 1993
Purification and characterization of DNA topoisomerase V. An enzyme from the hyperthermophilic prokaryote Methanopyrus kandleri that resembles eukaryotic topoisomerase I. journal February 1994
Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog journal November 2002
Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases journal January 2006
Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism journal September 2007
Automated Structure Solution With autoSHARP book January 2006
Data processing and analysis with the autoPROC toolbox journal March 2011
An RNA topoisomerase. journal September 1996
Cellular roles of DNA topoisomerases: a molecular perspective journal June 2002
Overview of the CCP 4 suite and current developments journal March 2011
Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. journal December 1990