GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- DOE - Office Of Science; National Science Foundation (NSF)
- OSTI ID:
- 1901019
- Journal Information:
- J. Med. Chem., Vol. 65, Issue (17)
- Country of Publication:
- United States
- Language:
- ENGLISH
Similar Records
Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist
CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches
Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
Journal Article
·
2014
· Accounts of Chemical Research
·
OSTI ID:1154887
+5 more
CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches
Journal Article
·
2019
· BMC Molecular and Cell Biology
·
OSTI ID:1577174
+14 more
Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
Journal Article
·
2018
· Molecular Pharmacology
·
OSTI ID:1438914
+2 more