skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Va

Journal Article · · ACS Omega

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Science Foundation (NSF)
OSTI ID:
1901014
Journal Information:
ACS Omega, Vol. 7, Issue (38)
Country of Publication:
United States
Language:
ENGLISH

References (33)

Conformational changes in ornithine decarboxylase enable recognition by antizyme journal January 1990
Rapid exchange of subunits of mammalian ornithine decarboxylase. journal February 1994
Equilibrium between active and inactive forms of rat liver ornithine decarboxylase mediated by L-ornithine and salts journal October 1985
Polyamine metabolism and cancer: treatments, challenges and opportunities journal September 2018
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme journal January 1995
Degradation of ornithine decarboxylase: exposure of the C-terminal target by a polyamine-inducible inhibitory protein journal April 1993
Expression of a Novel Human Ornithine Decarboxylase-like Protein in the Central Nervous System and Testes journal October 2001
Structural Elements of Antizymes 1 and 2 Are Required for Proteasomal Degradation of Ornithine Decarboxylase journal November 2002
Structural basis of antizyme-mediated regulation of polyamine homeostasis journal August 2015
Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1 journal October 2015
Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development journal March 2021
Integration, scaling, space-group assignment and post-refinement journal January 2010
Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane journal December 2021
Features and development of Coot journal March 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Modeling Analytical Ultracentrifugation Experiments with an Adaptive Space-Time Finite Element Solution of the Lamm Equation journal September 2005
Modeling Analytical Ultracentrifugation Experiments with an Adaptive Space-Time Finite Element Solution for Multicomponent Reacting Systems journal July 2008
A two-dimensional spectrum analysis for sedimentation velocity experiments of mixtures with heterogeneity in molecular weight and shape journal February 2009
Parsimonious regularization using genetic algorithms applied to the analysis of analytical ultracentrifugation experiments conference July 2007
Monte Carlo analysis of sedimentation experiments journal June 2007
Parallel computational techniques for the analysis of sedimentation velocity experiments in UltraScan journal July 2007
Sedimentation velocity analysis of highly heterogeneous systems journal December 2004
Prevention of Rapid Intracellular Degradation of ODC by a Carboxyl-Terminal Truncation journal March 1989
Crystal structure of human ornithine decarboxylase at 2.1 å resolution: structural insights to antizyme binding journal January 2000
Neuropathy‐associated histidyl‐tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish journal July 2020
Modulation of aggregate size- and shape-distributions of the amyloid-β peptide by a designed β-sheet breaker journal February 2009
An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling journal April 2017
Characterization of Reversible Associations by Sedimentation Velocity with UltraScan journal June 2010
Functional Roles of the Dimer-Interface Residues in Human Ornithine Decarboxylase journal August 2014
Regulation of Ornithine Decarboxylase journal May 2006
Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease journal July 2021
Expanding the phenotype: Four new cases and hope for treatment in Bachmann‐Bupp syndrome journal September 2021
Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features journal September 2018