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MolProbity: More and better reference data for improved all-atom structure validation: PROTEIN SCIENCE.ORG
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journal
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November 2017 |
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Matriptase and MET are prominently expressed at the site of bone metastasis in renal cell carcinoma: immunohistochemical analysis
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September 2014 |
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Mechanisms of hyperkalemia caused by nafamostat mesilate
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December 1995 |
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
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April 2020 |
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D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction
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January 2021 |
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A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
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May 2020 |
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Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin
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journal
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January 2021 |
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An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19
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journal
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September 2020 |
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Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology
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journal
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November 2011 |
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The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
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journal
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September 2007 |
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HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase
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journal
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October 2013 |
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Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis
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journal
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August 2020 |
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SARS-CoV-2 cell tropism and multiorgan infection
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journal
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March 2021 |
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A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry
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journal
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June 2021 |
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SARS-CoV-2 receptor ACE2 is co-expressed with genes related to transmembrane serine proteases, viral entry, immunity and cellular stress
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journal
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December 2020 |
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Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
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journal
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August 2005 |
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Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation
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journal
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May 2013 |
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Protease specificity determination by using cellular libraries of peptide substrates (CLiPS)
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May 2006 |
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Evolutionary Divergence of Substrate Specificity within the Chymotrypsin-like Serine Protease Fold
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journal
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November 1997 |
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Bovine Proenteropeptidase Is Activated by Trypsin, and the Specificity of Enteropeptidase Depends on the Heavy Chain
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December 1997 |
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Distinct Roles of N-Glycosylation at Different Sites of Corin in Cell Membrane Targeting and Ectodomain Shedding
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January 2015 |
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Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease
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journal
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September 2020 |
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Homology modeling and structure-based design improve hydrophobic interaction chromatography behavior of integrin binding antibodies
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August 2018 |
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Deciphering key features in protein structures with the new ENDscript server
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journal
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April 2014 |
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The EMBL-EBI search and sequence analysis tools APIs in 2019
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journal
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April 2019 |
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Three Essential Resources to Improve Differential Scanning Fluorimetry (DSF) Experiments
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preprint
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March 2020 |
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Phaser crystallographic software
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July 2007 |
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A neutron-diffraction study of the low-cycle fatigue behaviour of an austenitic stainless steel 316
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August 2010 |
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Bromhexine Hydrochloride Tablets for the Treatment of Moderate COVID‐19: An Open‐Label Randomized Controlled Pilot Study
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October 2020 |
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The role of type II transmembrane serine protease-mediated signaling in cancer
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journal
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December 2016 |
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Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits
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October 2020 |
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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
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journal
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July 2020 |
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TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
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journal
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May 2020 |
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Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19
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journal
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May 2020 |
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SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation
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journal
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April 2021 |
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TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes
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journal
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November 2019 |
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Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium
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journal
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September 2006 |
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Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2
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journal
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December 2010 |
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TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein
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journal
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January 2014 |
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Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
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journal
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May 2011 |
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Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain
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journal
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July 2007 |
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Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis
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journal
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July 2015 |
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The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis
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journal
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November 2014 |
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Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases
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journal
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October 2015 |
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Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2
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journal
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June 2017 |
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Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity
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journal
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August 2017 |
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SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells
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journal
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January 2021 |
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Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
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journal
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October 2009 |
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TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells
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journal
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June 2010 |
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TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
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journal
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July 2020 |
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Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza
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journal
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April 2021 |
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Inhibition of Membrane-Type Serine Protease 1/Matriptase by Natural and Synthetic Protease Inhibitors
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journal
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January 2003 |
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The Evolution of the Scavenger Receptor Cysteine-Rich Domain of the Class A Scavenger Receptors
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journal
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July 2015 |
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TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein
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journal
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February 2021 |
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N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding
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journal
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June 2018 |