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Protein–excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development
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October 2011 |
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Therapeutic protein aggregation: mechanisms, design, and control
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journal
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July 2014 |
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Monoclonal antibodies as therapeutic agents in oncology and antibody gene therapy
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journal
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January 2007 |
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Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development
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journal
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October 2010 |
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No ordinary proteins: Adsorption and molecular orientation of monoclonal antibodies
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journal
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August 2021 |
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Interactions of formulation excipients with proteins in solution and in the dried state
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journal
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October 2011 |
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Kinetics of hydrolysis of polyoxyethylene (20) sorbitan fatty acid ester surfactants
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journal
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April 2011 |
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Dynamic Properties of Novel Excipient Suggest Mechanism for Improved Performance in Liquid Stabilization of Protein Biologics
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journal
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November 2018 |
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Surface Activity of a Monoclonal Antibody
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journal
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December 2009 |
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Liquid Surfaces and Interfaces: Synchrotron X-ray Methods
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book
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September 2012 |
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Monolayer–multilayer transitions in a lung surfactant model: IR reflection–absorption spectroscopy and atomic force microscopy
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journal
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January 2005 |
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Use of Poloxamer Polymers to Stabilize Recombinant Human Growth Hormone Against Various Processing Stresses
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journal
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January 1997 |
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Impact of Polysorbate 80 Grade on the Interfacial Properties and Interfacial Stress Induced Subvisible Particle Formation in Monoclonal Antibodies
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journal
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February 2021 |
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Emerging Challenges and Innovations in Surfactant-mediated Stabilization of Biologic Formulations
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journal
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April 2022 |
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The liquid surface/interface spectrometer at ChemMatCARS synchrotron facility at the Advanced Photon Source
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journal
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August 2003 |
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Protein drug stability: a formulation challenge
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journal
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April 2005 |
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Armoring the Interface with Surfactants to Prevent the Adsorption of Monoclonal Antibodies
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journal
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February 2020 |
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Antibody adsorption on the surface of water studied by neutron reflection
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journal
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January 2017 |
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Interfacial dilatational deformation accelerates particle formation in monoclonal antibody solutions
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journal
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January 2016 |
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The Degradation of Polysorbates 20 and 80 and its Potential Impact on the Stability of Biotherapeutics
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journal
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March 2011 |
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Instability, stabilization, and formulation of liquid protein pharmaceuticals
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journal
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August 1999 |
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The Role of Polysorbate 80 and HPβCD at the Air-Water Interface of IgG Solutions
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journal
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August 2012 |
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Free Fatty Acid Particles in Protein Formulations, Part 2: Contribution of Polysorbate Raw Material
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journal
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February 2015 |
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A synchrotron x-ray liquid surface spectrometer
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journal
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December 1997 |
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Key interactions of surfactants in therapeutic protein formulations: A review
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journal
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November 2015 |
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Micelle-Associated Protein in Epoetin Formulations: A Risk Factor for Immunogenicity?
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journal
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December 2003 |
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Kinetics of adsorption of globular proteins at liquid/fluid interfaces
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journal
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July 2001 |
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Driving Force Behind Adsorption-Induced Protein Unfolding: A Time-Resolved X-ray Reflectivity Study on Lysozyme Adsorbed at an Air/Water Interface
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journal
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December 2008 |
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Protein aggregation—Pathways and influencing factors
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journal
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May 2010 |
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Polysorbate degradation in biotherapeutic formulations: Identification and discussion of current root causes
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journal
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December 2018 |
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Effect of concentration and denaturation on adsorption and surface tension of bovine serum albumin
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journal
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April 2003 |
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Role of naturally occurring osmolytes in protein folding and stability
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journal
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November 2009 |
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Amino-Acid-Incorporating Nonionic Surfactants for Stabilization of Protein Pharmaceuticals
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journal
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June 2016 |
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Protein aggregation and its inhibition in biopharmaceutics
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journal
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January 2005 |
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Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation
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journal
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September 2020 |
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Ester Hydrolysis of Polysorbate 80 in mAb Drug Product: Evidence in Support of the Hypothesized Risk After the Observation of Visible Particulate in mAb Formulations
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journal
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August 2014 |
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Meeting report on protein particles and immunogenicity of therapeutic proteins: Filling in the gaps in risk evaluation and mitigation
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journal
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September 2010 |
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Small-Scale Tools to Assess the Impact of Interfacial and Shear Stress on Biologic Drug Products
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journal
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May 2019 |
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Predicting the Agitation-Induced Aggregation of Monoclonal Antibodies Using Surface Tensiometry
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journal
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August 2015 |
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Notorious but not understood: How liquid-air interfacial stress triggers protein aggregation
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journal
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February 2018 |
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Modulation of Protein Adsorption by Poloxamer 188 in Relation to Polysorbates 80 and 20 at Solid Surfaces
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journal
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April 2014 |
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A Comprehensive Assessment of All-Oleate Polysorbate 80: Free Fatty Acid Particle Formation, Interfacial Protection and Oxidative Degradation
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journal
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March 2021 |
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Protein-Silicone Oil Interactions: Comparative Effect of Nonionic Surfactants on the Interfacial Behavior of a Fusion Protein
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journal
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April 2013 |
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Polysorbate 20 prevents the precipitation of a monoclonal antibody during shear
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journal
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November 2009 |
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Protein-protein interactions controlling interfacial aggregation of rhIL-1ra are not described by simple colloid models
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journal
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March 2018 |
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A Method To Measure Protein Unfolding at an Air–Liquid Interface
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journal
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September 2016 |
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Competitive Surface Activity of Monoclonal Antibodies and Nonionic Surfactants at the Air–Water Interface Determined by Interfacial Rheology and Neutron Reflectometry
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journal
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June 2020 |
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An Approach to Mitigate Particle Formation on the Dilution of a Monoclonal Antibody Drug Product in an IV Administration Fluid
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journal
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March 2016 |
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Linking aggregation and interfacial properties in monoclonal antibody-surfactant formulations
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journal
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August 2019 |
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Surfactant Impact on Interfacial Protein Aggregation and Utilization of Surface Tension to Predict Surfactant Requirements for Biological Formulations
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journal
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November 2020 |
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Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective
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journal
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March 2019 |
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Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
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journal
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August 2014 |
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Effects of Hydrophobic Tail Length Variation on Surfactant-Mediated Protein Stabilization
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journal
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October 2020 |
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Molecular origins of surfactant-mediated stabilization of protein drugs
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journal
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October 2011 |