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Homology Modelling of the GABA Transporter and Analysis of Tiagabine Binding
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May 2010 |
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In Vitro Assays for the Functional Characterization of the Dopamine Transporter (DAT)
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December 2017 |
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The action of γ-Aminobutyric acid on cortical neurones
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May 1967 |
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Inhibitors of the GABA uptake systems
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June 1980 |
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Gaba Transporter Heterogeneity: Pharmacology and Cellular Localization
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October 1996 |
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Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1
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October 1994 |
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Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes.
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November 1992 |
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Inhibition of γ-aminobutyric acid uptake: anatomy, physiology and effects against epileptic seizures
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October 2003 |
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γ-Aminobutyric acid transporters as relevant biological target: Their function, structure, inhibitors and role in the therapy of different diseases
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September 2020 |
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Structure modeling of γ-aminobutyric acid transporters – Molecular basics of ligand selectivity
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September 2020 |
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Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding
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July 2021 |
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Establishment of a novel microscale thermophoresis ligand-binding assay for characterization of SLC solute carriers using oligopeptide transporter PepT1 (SLC15 family) as a model system
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July 2018 |
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Novel Allosteric Ligands of γ-Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries
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October 2018 |
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Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2
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November 2017 |
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Identification of a Novel Allosteric Modulator of the Human Dopamine Transporter
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June 2019 |
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Orally Active and Potent Inhibitors of γ-Aminobutyric Acid Uptake
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May 1985 |
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A Binding Mode Hypothesis of Tiagabine Confirms Liothyronine Effect on γ-Aminobutyric Acid Transporter 1 (GAT1)
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February 2015 |
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Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
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July 2005 |
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X-ray structure of dopamine transporter elucidates antidepressant mechanism
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September 2013 |
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Structural basis for action by diverse antidepressants on biogenic amine transporters
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October 2013 |
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Neurotransmitter and psychostimulant recognition by the dopamine transporter
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May 2015 |
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X-ray structures and mechanism of the human serotonin transporter
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April 2016 |
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Screening and large-scale expression of membrane proteins in mammalian cells for structural studies
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October 2014 |
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GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition
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May 2008 |
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Is there more to gaba than synaptic inhibition?
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September 2002 |
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Excitatory actions of gaba during development: the nature of the nurture
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September 2002 |
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Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters
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April 2021 |
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The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter
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August 2021 |
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Structural insights into the inhibition of glycine reuptake
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March 2021 |
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Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs
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September 1999 |
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GABAergic Mechanisms in Epilepsy
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December 2001 |
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Inhibitory role for GABA in autoimmune inflammation
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February 2010 |
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The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor
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July 2019 |
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Channel behavior in a gamma-aminobutyrate transporter.
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January 1996 |
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Tyrosine 140 of the γ-Aminobutyric Acid Transporter GAT-1 Plays a Critical Role in Neurotransmitter Recognition
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June 1997 |
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High Selectivity of the γ-Aminobutyric Acid Transporter 2 (GAT-2, SLC6A13) Revealed by Structure-based Approach
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November 2012 |
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Functional Defects in the External and Internal Thin Gates of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Can Compensate Each Other
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February 2013 |
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Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation
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June 2015 |
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An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport
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March 2017 |
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Transmembrane Domain I of the γ-Aminobutyric Acid Transporter GAT-1 Plays a Crucial Role in the Transition between Cation Leak and Transport Modes
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February 2003 |
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Gat1 (Gaba:Na+:Cl−) Cotransport Function
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September 1999 |
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Gat1 (Gaba:Na+:Cl−) Cotransport Function
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September 1999 |
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AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
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November 2021 |
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GABAergic Synchronization in Epilepsy
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January 2016 |
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Phaser crystallographic software
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July 2007 |
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XDS
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January 2010 |
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PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
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How good are my data and what is the resolution?
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June 2013 |
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THE UPTAKE OF [3H]GABA BY SLICES OF RAT CEREBRAL CORTEX
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October 1968 |
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A Review of the Preclinical Pharmacology of Tiagabine: A Potent and Selective Anticonvulsant GABA Uptake Inhibitor
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June 1995 |
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The effects of Factor I and of gamma-aminobutyric acid on smooth muscle preparations
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January 1959 |
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Identification and Selective Inhibition of the Channel Mode of the Neuronal GABA Transporter 1
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September 2005 |
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Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction
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April 2015 |
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SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation
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July 2011 |
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A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation
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December 2008 |
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Cloning and Expression of a Rat Brain GABA Transporter
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September 1990 |
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Molecular Structure and Physiological Functions of GABA B Receptors
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July 2004 |
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A non‐helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition
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November 2020 |
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The GABA Transporter and its Inhibitors
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October 2000 |
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Structure, Function, and Modulation of γ-Aminobutyric Acid Transporter 1 (GAT1) in Neurological Disorders: A Pharmacoinformatic Prospective
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September 2018 |
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GABA and Glutamate Transporters in Brain
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January 2013 |
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Structure and Gating Dynamics of Na+/Cl– Coupled Neurotransmitter Transporters
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September 2019 |
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Plasticity of GABA transporters: an unconventional route to shape inhibitory synaptic transmission
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May 2014 |
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A Gut Feeling about GABA: Focus on GABAB Receptors
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January 2010 |
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Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics
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October 2019 |